A pharmacoepidemiological study of the impact of psychotropic drugs on suicide reattempts.

2021 ◽  
Author(s):  
Alice Demesmaeker ◽  
Emmanuel Chazard ◽  
Guillaume Vaiva ◽  
Ali Amad
Keyword(s):  
Psychotropic Drugs ◽  
Pharmacoepidemiological Study ◽  
The Impact

Pharmacoepidemiology of psychotropic drugs: examples of current research challenges on major public health issues

2009 ◽  
Vol 18 (2) ◽  
pp. 107-113 ◽  
Author(s):  
Hélène Verdoux ◽  
Marie Tournier ◽  
Bernard Bégaud
Keyword(s):  
Public Health ◽  
Prenatal Exposure ◽  
Psychotropic Drugs ◽  
Antipsychotic Drugs ◽  
Population Level ◽  
Health Issues ◽  
Review Of The Literature ◽  
Research Challenges ◽  
The Impact

SummaryBackground– As a large number of persons are exposed to prescribed psychotropic drugs, their utilisation and impact should be further explored at the population level.Aims– To illustrate the interest of pharmacoepidemiological studies of psychotropic drugs by selected examples of major public health issues.Method– Selective review of the literature. Results – Many questions remain unsolved regarding the behavioural teratogenicity of prenatal exposure to psychotropic drugs, the impact of their increasing use in children, the long-term cognitive consequences of exposure to benzodiazepines, and the risks associated with extension of indications of antipsychotic drugs.Conclusion– Pharmacoepidemiological studies need to be further developed owing to the large number of public health questions raised by the extensive and expanding use of psychotropic drugs.

A systematic review on the impact of psychotropic drugs on electroencephalogram waveforms in psychiatry

2016 ◽  
Vol 128 (7) ◽  
pp. 656-664 ◽  
Author(s):  
Rohit Aiyer ◽  
Vladan Novakovic ◽  
Robert L. Barkin
Keyword(s):  
Systematic Review ◽  
Psychotropic Drugs ◽  
The Impact

Screening for Mental Illness: The Merger of Eugenics and the Drug Industry

2005 ◽  
Vol 7 (2) ◽  
pp. 111-124 ◽  
Author(s):  
Vera Hassner Sharav
Keyword(s):  
Mental Illness ◽  
Psychotropic Drugs ◽  
Treatment Plan ◽  
Medication Treatment ◽  
Faith Based ◽  
United States Population ◽  
Behavioral Abnormalities ◽  
Children First ◽  
And Behavior ◽  
The Impact

The implementation of a recommendation by the President’s New Freedom Commission (NFC) to screen the entire United States population—children first—for presumed, undetected, mental illness is an ill-conceived policy destined for disastrous consequences. The “pseudoscientific” methods used to screen for mental and behavioral abnormalities are a legacy from the discredited ideology of eugenics. Both eugenics and psychiatry suffer from a common philosophical fallacy that undermines the validity of their theories and prescriptions. Both are wed to a faith-based ideological assumption that mental and behavior manifestations are biologically determined, and are, therefore, ameliorated by biological interventions. NFC promoted the Texas Medication Algorithm Project (TMAP) as a “model” medication treatment plan. The impact of TMAP is evident in the skyrocketing increase in psychotropic drug prescriptions for children and adults, and in the disproportionate expenditure for psychotropic drugs. The New Freedom Commission’s screening for mental illness initiative is, therefore, but the first step toward prescribing drugs. The escalating expenditure for psychotropic drugs since TMAP leaves little doubt about who the beneficiaries of TMAP are. Screening for mental illness will increase their use.

Quality of Life for People With Dementia Living in Residential and Nursing Home Care: The Impact of Performance on Activities of Daily Living, Behavioral and Psychological Symptoms, Language Skills, and Psychotropic Drugs

2001 ◽  
Vol 13 (1) ◽  
pp. 93-106 ◽  
Author(s):  
Clive Ballard ◽  
John O'Brien ◽  
Ian James ◽  
Pat Mynt ◽  
Marisa Lana ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Activities Of Daily Living ◽  
Psychotropic Drugs ◽  
Daily Living ◽  
Psychological Symptoms ◽  
Well Being ◽  
Nursing Home Care ◽  
People With Dementia ◽  
The Impact

Many people with dementia reside in care facilities. Little is known about how key parameters impact upon their quality of life (QOL). All 209 people with dementia in six facilities received a standardized assessment (Neuropsychiatric Inventory [NPI], Barthel Scale, psychotropic drugs). One hundred twelve residents were assessed using Dementia Care Mapping, an observational method for QOL indices. Lower performance on activities of daily living (reduced well-being [WB] r = +0.39, p < .0001; social withdrawal [SW] r = +0.42, p < .0001; engagement in activities [EA] r = +0.31, p = .001) and taking psychotropics (WB 2.5 vs. 3.2, t = .2.3, p = .02; SW 11.4% vs. 2.7%, t = 3.0, p = .004; EA 56.5% vs. 71.9%; t = 3.5, p = .001) were associated with reduced QOL, but symptoms from the NPI were not. More focused prescribing of psychotropics and better staff training are essential.

scholarly journals Erectile dysfunction in patients taking psychotropic drugs and treated with phosphodiesterase-5 inhibitors

2018 ◽  
Vol 90 (1) ◽  
pp. 44 ◽  
Author(s):  
Rossella Mazzilli ◽  
Gloria Angeletti ◽  
Soraya Olana ◽  
Michele Delfino ◽  
Virginia Zamponi ◽  
...  
Keyword(s):  
Erectile Dysfunction ◽  
Psychotropic Drugs ◽  
Remission Rate ◽  
Antidepressant Drugs ◽  
Serum Testosterone ◽  
Hormonal Profile ◽  
Group A ◽  
Group B ◽  
The Impact ◽  
Group D

Objectives: The aim of this study was to assess the prevalence of patients with Erectile Dysfunction (ED) receiving psychotropic drugs, the impact of these drugs on hormonal profile, and the efficacy of PDE5-i in these patients. Materials and methods: We recruited 1872 patients referring for ED to our Andrology Unit. Assessment included serum testosterone, gonadotropins, TSH, prolactin, and PSA, and the IIEF-5 questionnaire for ED diagnosis. Inclusion criteria were age 21-75 years and IIEF-5 total score ≤ 21; exclusion criteria included hypogonadism, diabetes mellitus, previous prostatectomy, other medication intake, and ED diagnosis prior to psychotropic drug treatment. Efficacy was rated with the IIEF-5 (remission: total score ≥ 22). Results: The prevalence of ED patients treated with psychotropic drugs since ≥ 3 months was 9.5% (178/1872), subdivided according to the drugs used into: Group A, 16 patients treated with atypical antipsychotics (9.0%); Group B, 55 patients with benzodiazepines (30.9%); Group C, 33 patients with antidepressant drugs (18.5%); and Group D, 74 patients with multiple psychotropic drugs (41.6%). Patients in Group A were significantly younger than other groups (p < 0.05). The hormonal profile presented only higher prolactin level in patients treated with antipsychotics, alone or in combination (p < 0.05). Overall, 146 patients received PDE5-i. Remission rate, after three months of treatment, was significantly higher in Group B compared to C and D groups (p < 0.05). Conclusions: A substantial portion of patients receiving psychotropic drugs show ED. Sexual performance in these patients benefits from PDE5-i. Age, effects of psychiatric disorders, psychotropic drugs, and PDE5-i treatment modality accounted for variability of response in this sample.

Epilogue: Life after Life

2020 ◽  
pp. 335-340
Author(s):  
Robert H. Abzug
Keyword(s):  
Psychotropic Drugs ◽  
The Impact

This epilogue recounts the fate of May’s work since his death, a period of declining and then renewed interest that continues today. It deals with changes in publishing, therapy, the rise of Prozac and other psychotropic drugs and their impact on psychotherapy, the impact of HMOs, and the renewal of interest created by the circulation of his books through Amazon.com and other online booksellers. It also points to the circulation of his ideas in blogs and vlogs as well as in comments on bookstore sites.

Psychiatric Morbidity and Survival After Surgery for Esophageal Cancer: A Population-Based Cohort Study

2015 ◽  
Vol 33 (5) ◽  
pp. 448-454 ◽  
Author(s):  
Anna Wikman ◽  
Rickard Ljung ◽  
Asif Johar ◽  
Ylva Hellstadius ◽  
Jesper Lagergren ◽  
...  
Keyword(s):  
Risk Factors ◽  
Esophageal Cancer ◽  
Patient Care ◽  
Psychotropic Drugs ◽  
Cumulative Incidence ◽  
Psychiatric Morbidity ◽  
Tumor Stage ◽  
Population Based ◽  
Health Care Use ◽  
The Impact

Purpose To determine the cumulative incidence of and risk factors for psychiatric morbidity and establish the impact on survival among surgically treated patients with esophageal cancer. Patients and Methods A nationwide Swedish cohort of 1,615 patients who underwent surgery for esophageal cancer between 1987 and 2010 with follow-up until 2012 was linked to national health registries for information on psychiatric morbidity (inferred from mental health care use). Multivariable logistic regressions were used to determine potential risk factors for postoperative psychiatric morbidity. A multivariable-adjusted Cox proportional hazard model was used to analyze overall survival. Results In patients without a history of psychiatric morbidity, the 2-year cumulative incidence for treatment in psychiatric in-patient care was 2.5%, for psychiatric out-patient care was 4.2%, and for treatment with psychotropic drugs was 32.3%. Married patients were less likely to be treated postoperatively in psychiatric in-patient care (odds ratio [OR], 0.42; 95% CI, 0.22 to 0.80) or out-patient care (OR, 0.41; 95% CI, 0.17 to 1.02), whereas patients with higher tumor stage were more likely to be treated in psychiatric out-patient care (OR, 4.99; 95% CI, 1.16 to 21.38) or with psychotropic drugs (OR, 2.78; 95% CI, 1.10 to 7.01). Bearing in mind possible residual confounding, new-onset psychiatric morbidity was associated with mortality (hazard ratio [HR], 1.65 [95% CI, 1.17 to 2.33] for treatment in psychiatric in-patient care; HR, 1.93 [95% CI, 1.18 to 3.16] for treatment in psychiatric out-patient care; and HR, 2.77 [95% CI, 1.72 to 4.44] for treatment with psychotropic drugs). Conclusion These results highlight the importance of recognizing and addressing psychiatric morbidity in surgically treated patients with esophageal cancer.

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