The Impact of Nonsteroidal Anti-inflammatory Drugs on Older Adult Trauma Patients With Hip Fractures

Abstract The article is the result of research on the impact of non-pharmacological therapies for diseases of the locomotor system on the prescribed drug use and lifestyles of the patients of the sanatoria in Busko-Zdroj. The reported research uses primary and secondary measures. The former includes the assessment of the impact of non-pharmacological sanatorium treatments for locomotor system diseases on the use of prescribed drug regimes, while the latter is aimed at assessing the patients’ quality of life. The research was conducted on adult patients of both genders in the sanatoria in Busko-Zdroj. The subjects were patients suffering from disorders of the musculoskeletal system such as rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, osteoporosis and discopathies. The research included two visits, the first at the start of the research and the second at the end of the research. The patients were examined for a period of three consecutive weeks. The study involved 170 patients, 50% of them were women and 50% men. A decline in the use of painkillers and anti-inflammatory drugs makes a very interesting finding. After the first week, as many as 38% of the examined patients limited the use of painkillers and/or anti-inflammatory drugs. After the second week, 62% of the patients reduced the use of the drugs, and after the third week of treatment, up to 90% of the patients did so. The improvement of patients’ lives is noticeable in the psychological, physical and motor fields.

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Impact of Anti-Inflammatory Drugs on Pyogenic Vertebral Osteomyelitis: A Prospective Cohort Study

International Journal of Rheumatology ◽

10.1155/2016/9345467 ◽

2016 ◽

Vol 2016 ◽

pp. 1-4

Author(s):

Aurélien Dinh ◽

Maxime Jean ◽

Frédérique Bouchand ◽

Benjamin Davido ◽

Alexis Descatha ◽

...

Keyword(s):

Clinical Presentation ◽

Diagnostic Delay ◽

Vertebral Osteomyelitis ◽

Diagnosis Delay ◽

Cure Rate ◽

Pyogenic Vertebral Osteomyelitis ◽

Inflammatory Drugs ◽

Anti Inflammatory ◽

A Prospective Study ◽

The Impact

Objective. Pyogenic vertebral osteomyelitis (PVO) are frequently misdiagnosed and patients often receive anti-inflammatory drugs for their back pain. We studied the impact of these medications. Methods. We performed a prospective study enrolling patients with PVO and categorized them depending on their drugs intake. Then, we compared diagnosis delay, clinical presentation at hospitalization, incidence of complications, and cure rate. Results. In total, 79 patients were included. Multivariate analysis found no correlation between anti-inflammatory drug intake and diagnosis delay, clinical presentation, complications, or outcome. Conclusion. Anti-inflammatory drugs intake does not affect diagnostic delay, severity at diagnosis, or complications of PVO.

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The Impact on Health-Related Quality of Life from Non-Steroidal Anti-Inflammatory Drugs, Methotrexate, or Steroids in Treatment for Juvenile Idiopathic Arthritis

Journal of Pediatric Psychology ◽

10.1093/jpepsy/jsj014 ◽

2005 ◽

Vol 31 (3) ◽

pp. 262-271 ◽

Cited By ~ 9

Author(s):

Russ Riddle ◽

Christina N. Ryser ◽

Anne A. Morton ◽

J. D. Sampson ◽

Richard H. Browne ◽

...

Keyword(s):

Quality Of Life ◽

Juvenile Idiopathic Arthritis ◽

Health Related Quality ◽

Related Quality ◽

Health Related ◽

Inflammatory Drugs ◽

Anti Inflammatory ◽

The Impact

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Analysis of non-steroidal anti-inflammatory drug use in hospitalized patients and perception of their risk

Interdisciplinary Toxicology ◽

10.2478/intox-2013-0022 ◽

2013 ◽

Vol 6 (3) ◽

pp. 141-144 ◽

Cited By ~ 11

Author(s):

Zoltán Varga ◽

Milan Kriška ◽

Viera Kristová ◽

Miriam Petrová

Keyword(s):

Adverse Effects ◽

Questionnaire Study ◽

Pharmacological Agents ◽

Analgesic Treatment ◽

Increased Risk ◽

Chi Squared ◽

History Of ◽

Inflammatory Drugs ◽

Anti Inflammatory ◽

The Impact

ABSTRACT Non-steroidal anti-inflammatory drugs (NSAIDs) belong to the most widely prescribed and used pharmacological agents worldwide. Data gathered in the last decade show increased incidence of thrombotic events during NSAID administration. Analysis of NSAID usage and assessment of risk for development of cardiovascular adverse effects is needed for improving patient safety. For limiting the impact of adverse effects on the health of patients, NSAID users should be informed about the possible adverse effects and their symptoms to ensure early detection and treatment discontinuation. In the presented study, we retrospectively analyzed the administration of NSAIDs in a group of patients (n=428) in need of analgesic treatment hospitalized at a department of internal medicine. Factors increasing the risk for cardiovascular adverse effects were also investigated. A separate questionnaire study was conducted to gather information concerning the knowledge of hospitalized NSAID users (n=251) about adverse effects of the medication used. For purpose of comparison, we conducted a similar study in a group of 234 random respondents from a shopping center. Data were evaluated using descriptive statistics, Student´s t-test and chi-squared test. Our results suggest that the majority of patients treated with NSAIDs have factors indicating increased risk of development of adverse effects, most commonly arterial hypertension (58.2% of patients). The results of our questionnaire study show limited knowledge of NSAID users about the risk of the therapy. Nearly half of the respondents were unaware of any adverse effects. We consider as alarming that only a limited number of respondents were informed by their physician or pharmacist about the possible risks of treatment. In conclusion, we found that hospitalized NSAID users often have a history of diseases predisposing to the development of cardiovascular adverse effects of NSAIDs. Despite this, their knowledge about the risk of treatment is insufficient.

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