scholarly journals Financial Toxicity among Patients with Bladder Cancer: Reasons for Delay in Care and Effect on Quality of Life

2018 ◽  
Vol 199 (5) ◽  
pp. 1166-1173 ◽  
Author(s):  
Marianne M. Casilla-Lennon ◽  
Seul Ki Choi ◽  
Allison M. Deal ◽  
Jeannette T. Bensen ◽  
Gopal Narang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bladder Cancer ◽  
Financial Toxicity

MP86-05 THE RELATIONSHIP BETWEEN FINANCIAL TOXICITY AND QUALITY OF LIFE AMONG BLADDER CANCER PATIENTS

2017 ◽  
Vol 197 (4S) ◽  
Author(s):  
Marianne Casilla-Lennon ◽  
Seul Ki Cho ◽  
Allison Deal ◽  
Gopal Narang ◽  
Jeannette Bensen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bladder Cancer ◽  
Cancer Patients ◽  
Financial Toxicity ◽  
The Relationship

scholarly journals Quality of Life and Health State Utilities in Bladder Cancer

2021 ◽  
pp. 1-16
Author(s):  
Angela B. Smith ◽  
Sean McCabe ◽  
Allison M. Deal ◽  
Amy Guo ◽  
Kathryn H. Gessner ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bladder Cancer ◽  
Metastatic Disease ◽  
Cost Effective ◽  
Health State ◽  
Financial Toxicity ◽  
Metastatic Bladder Cancer ◽  
Health State Utilities ◽  
Muscle Invasive

BACKGROUND: Bladder cancer treatments may variably impact health-related quality of life (QOL). OBJECTIVE: To characterize the quality of life of patients with bladder cancer at various time points across the continuum of bladder cancer care from non-muscle-invasive disease to metastatic bladder cancer and develop utility scores to inform cost-effective analyses. METHODS: We performed a cross-sectional survey of bladder cancer patients in the Bladder Cancer Advocacy Network Patient Survey Network. Participants were classified into mutually exclusive health states based upon non-muscle invasive (NMIBC), muscle-invasive (MIBC), or metastatic bladder cancer and completed surveys of generic cancer and bladder cancer-specific quality of life, financial toxicity, and work impairment. We constructed generalized linear mixed models to identify patient, clinical, and treatment factors associated with quality of life over time and derived health state utilities. RESULTS: Among 911 self-identified patients with bladder cancer, overall QOL scores and function domains were worse among those with advanced cancer. Financial toxicity was similar among non-metastatic disease states. Work and activity impairment increased with advancing disease (13%and 12%among non-recurrent NMIBC to 63%and 31%for metastatic disease respectively; p <  0.01). On multivariable analysis, bowel-related QOL was diminished among patients with MIBC, with urinary symptoms and physical function most diminished among patients with metastatic disease. Patients with metastatic and MIBC experienced worse emotional functioning (p = 0.04; p = 0.048). Health state utilities were calculated, highest among those with non-recurrent NMIBC and lowest among those with metastatic disease. CONCLUSION: Generic and bladder cancer-specific QOL diminishes with advancing disease. Health state utility estimates derived from this study can inform shared decision making with patients and may be used to inform future cost-effective analyses.

Financial toxicity, financial well-being, and quality of life among bladder cancer patients.

2020 ◽  
Vol 38 (29_suppl) ◽  
pp. 133-133
Author(s):  
Reginald Tucker-Seeley ◽  
Weizhou Tang ◽  
Leora Steinberg ◽  
Stephanie Banks ◽  
Hilma Bolton ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bladder Cancer ◽  
Logistic Regression ◽  
Financial Burden ◽  
Well Being ◽  
Demographic Characteristics ◽  
Financial Toxicity ◽  
Logistic Regression Models ◽  
Long Course

133 Background: Due to a long course of surveillance, and for some patients, multimodal therapy with chemotherapy and surgery, bladder cancer (BC) can present a financial burden to the household. Yet, there are several terms used to describe this burden such as financial hardship and financial toxicity (FT); and it is unclear whether different measures of financial circumstances are correlated and whether they are associated with quality of life (QOL). The goal of this study was to determine whether FT and financial well-being (FWB) were correlated and to determine whether FT and FWB were similarly associated with QOL among BC patients. Methods: Patients that had BC treatment in the last 2 years were recruited from two NCI designated cancer centers for our study (N = 100). The Comprehensive Score for Financial Toxicity (COST) was used to assess FT, the Consumer Financial Protection Bureau’s (CFPB) FWB measure was used to assess FWB, and a BC-specific Functional Assessment of Cancer Therapy (FACT) questionnaire was used to assess physical, social, emotional, and functional domains of QOL. Bivariate analyses were conducted to determine the association among FT, FWB, and QOL; and separate logistic regression analyses predicting FT and FWB were used to determine the association between FT and FWB and each domain of QOL. Results: Bivariate results showed that FT and FWB were highly negatively correlated (r = -.76; p < .0001); however, only FWB was correlated with the total QOL score (p < .05). FT was correlated with physical (p < .01), emotional (p < .05), and functional (p < .05) QOL; and FWB was correlated with physical (p < .05) and functional (p < .05) QOL. Logistic regression models adjusted for socioeconomic and demographic characteristics showed that those reporting higher physical QOL (OR = 1.18; CI: 1.04-1.35) and higher functional QOL (OR = 1. 15; CI: 1.03-1.28) had higher odds of reporting high FWB. Conclusions: Given the surveillance and treatment processes for BC patients, it is important to better understand their financial circumstances as they are navigating and managing care. Our results suggest that physical and functional QOL is relevant for predicting FWB, but after considering socioeconomic and demographic characteristics, no domain of QOL was a significant predictor of FT among BC patients.

Financial Toxicity in Lung Cancer: An Assessment of Magnitude, Perception, and Impact on Quality of Life

2019 ◽  
Vol 105 (1) ◽  
pp. S20
Author(s):  
S.Z. Hazell ◽  
W. Fu ◽  
C. Hu ◽  
V. Peterson ◽  
B. Lee ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Financial Toxicity

scholarly journals Systematic Review: The Impact of Physical Activity on Risk and Health-Related Quality of Life in Bladder Cancer

2021 ◽  
pp. 1-10
Author(s):  
Marina Rodríguez Cintas ◽  
Sara Márquez ◽  
Javier González Gallego
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Systematic Review ◽  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Bladder Cancer ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

BACKGROUND: Sedentarism is an important modifiable risk factor in the struggle against cancer. In the last decades, the relationship between physical activity and different types of cancer has been investigated in depth. OBJECTIVE: To provide an overview of the literature on the effectiveness of physical activity in reducing the risk to develop bladder cancer and improving health-related quality of life in patients. METHODS: A systematic review was conducted through a search of the Embase, Cochrane, PubMed, Scopus, and Web of Science (WOS) databases to seek information and PRISMA system to delimitate the research. Outcomes included in searches were physical activity, tobacco consumption, obesity, body mass index, and metabolic syndrome, associated with bladder cancer and quality of life. RESULTS: Database searches identified 394 records, of which 75 were duplicated. A total of 280 articles were excluded based on abstract screening. An additional 16 full-text articles were excluded because they did not meet the eligibility criteria. Overall, 21 of the 23 studies included in the review reported beneficial effects of physical activity in bladder cancer. The majority of papers found that physical activity is a significant factor in reducing the risk of bladder cancer. Moreover, physical activity improves health-related quality of life in bladder cancer survivors, and diminishes both recurrence and mortality in those who engage in regular activity. Lastly, physical inactivity is associated with increased body mass index, obesity, metabolic syndrome, type 2 diabetes and unfavourable energy balance, which led to a greater probability of suffering from bladder cancer. CONCLUSIONS: These data reinforce the importance of promoting a healthy lifestyle to reduce the risk of bladder cancer and to improve survivorship and health-related quality of life of patients.

Association of pretreatment financial toxicity with time to treatment for patients with head and neck carcinoma and lung carcinoma.

2021 ◽  
Vol 39 (28_suppl) ◽  
pp. 131-131
Author(s):  
Sharon Lam ◽  
Nicolas Schlecht ◽  
Gregory Rosenblatt ◽  
Vikas Mehta
Keyword(s):  
Quality Of Life ◽  
Lung Carcinoma ◽  
Small Cell Lung Carcinoma ◽  
Treatment Delay ◽  
Small Cell ◽  
Financial Toxicity ◽  
Small Cell Lung ◽  
Cell Lung Carcinoma ◽  
Younger Age

131 Background: Financial toxicity (FT) describes objective and subjective burden of costs associated with medical care. Patients with head and neck cancer (HNC) and lung carcinoma are acutely impacted by FT, as these cancers disproportionately occur in populations that are poor, unemployed, and/or of minority backgrounds compared to patients with other cancers. Our group recently published results showing delay in time to treatment initiation (TTI) was associated with poorer survival in HNC patients. Another study reported that FT was associated with worse progression-free survival in non-small cell lung cancer patients. In this study, we sought to investigate the association between FT, TTI and clinical outcomes among HNC and lung carcinoma patients, as well as predictors of FT. Methods: A retrospective analysis of 140 patients diagnosed with either HNC or lung carcinoma between January 2007 and March 2018 with quality-of-life data collected prospectively at the time of radiation oncology treatment was conducted. Participants responded to a question about their experience on ‘financial difficulties’ with a 4-point Likert Scale within the European Organization for the Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30) quality of life assessment. FT was low when patients indicated ‘1’ (not at all) or ‘2’ (a little), and high if patients indicated ‘3’ (quite a bit), and ‘4’ (very much). Chi-square test and Student’s t-test were used to compare characteristics of patients with and without FT. The association between FT and TTI and survival outcomes were analyzed using the Kaplan-Meier methods and Cox proportional-hazards regression models. Results: The study sample included 70 patients with HNC (mean [SD] age, 64.3 [12.0]; 62.7% male) and 70 patients with lung carcinoma (mean [SD] age, 69.1 [10.2]; 38.0% male). Over half (N = 80, 55.2%) reported experiencing financial toxicity (64% HNC vs. 45.7% lung carcinoma). Younger age (< 60 years), having Medicaid, and having small-cell lung carcinoma were associated with greater FT (p = 0.049, p = 0.042, p = 0.034, respectively). Patients who reported having poorer health and quality of life also experienced greater FT (p = 0.030, p = 0.016, respectively). HNC patients who experienced greater FT were less likely to experience treatment delay (p = 0.035). After adjusting for age, sex, ethnicity, tumor site, and tumor stage, FT was associated with worse survival outcomes in all patients (HR = 1.52, 95% CI 1.06-2.19). Conclusions: Greater FT was associated with younger age, having Medicaid, and having small-cell lung carcinoma. HNC patients who experienced greater FT were less likely to experience treatment delay, which suggests that delay may not be a causative factor for the worsened survival seen with patients who report FT.

Sign in / Sign up

Export Citation Format

Share Document