The relationship between platelet–lymphocyte ratio and severity of erectile dysfunction

Abstract Background: It has been discovered that both inflammation and platelet aggregation could cause crucial effect on the occurrence and development of cardiovascular diseases. As a combination of platelet and lymphocyte, platelet-lymphocyte ratio (PLR) was proved to be correlated with the severity as well as prognosis of cardiovascular diseases. Exploring the relationship between PLR and in-hospital mortality in cardiac intensive care unit (CICU) patients was the purpose of this study. Method: PLR was calculated by dividing platelet count by lymphocyte count. All patients were grouped by PLR quartiles and the primary outcome was in-hospital mortality. The independent effect of PLR was determined by binary logistic regression analysis. The curve in line with overall trend was drawn by local weighted regression (Lowess). Subgroup analysis was used to determine the relationship between PLR and in-hospital mortality in different subgroups. Result: We included 5577 CICU patients. As PLR quartiles increased, in-hospital mortality increased significantly (Quartile 4 vs Quartile 1: 13.9 vs 8.3, P <0.001). After adjusting for confounding variables, PLR was proved to be independently associated with increased risk of in-hospital mortality (Quartile 4 vs Quartile 1: OR, 95% CI: 1.99, 1.46-2.71, P<0.001, P for trend <0.001). The Lowess curves showed a positive relationship between PLR and in-hospital mortality. The subgroup analysis revealed that patients with low Acute Physiology and Chronic Health Evaluation IV (APACHE IV) or with less comorbidities had higher risk of mortality for PLR. Further, PLR quartiles had positive relation with length of CICU stay (Quartile 4 vs Quartile 1: 2.7, 1.6-5.2 vs 2.1, 1.3-3.9, P<0.001), and the length of hospital stay (Quartile 4 vs Quartile 1: 7.9, 4.6-13.1 vs 5.8, 3.3-9.8, P<0.001). Conclusion: PLR was independently associated with in-hospital mortality in CICU patients.

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Interrelation of erectile dysfunction with obesity in patients with arterial hypertension

Terapevticheskii arkhiv ◽

10.26442/00403660.2018.12.000013 ◽

2018 ◽

Vol 90 (12) ◽

pp. 84-89

Author(s):

T A Alekseeva ◽

M A Shariya ◽

S I Gamidov ◽

E M Elfimova ◽

I V Starostin ◽

...

Keyword(s):

Computed Tomography ◽

Erectile Dysfunction ◽

Comparative Analysis ◽

Arterial Hypertension ◽

Erectile Function ◽

Preliminary Assessment ◽

Anthropometric Data ◽

Anthropometric Parameters ◽

The Relationship ◽

Severity Of Erectile Dysfunction

Aim. To study the relationship between the severity of erectile dysfunction and the anthropometric parameters of obesity in patients with arterial hypertension. Materials and methods. The study included 71 patients with different severity of erectile dysfunction, overweight and grade 1obesity and arterial hypertension. The anthropometric parameters were analyzed, the degree and characteristics of obesity were assessed according to data of multispiral computed tomography (MSCT), a preliminary assessment of erectile function was performed using the IIEF-5 questionnaire. Later the data of the questionnaire was compared with the in-depth urological study: the collection of anamnesis, examination and conduction of the pharmacodopplerography of the penis vessels. Results and discussion. Comparative analysis revealed statistically significant links between anthropometric data and the degree of abdominal obesity based on MSCT results (p

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The Relationship of Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio with Gastrointestinal Bleeding in Henoch-Schonlein Purpura

Iranian Journal of Pediatrics ◽

10.5812/ijp.8191 ◽

2016 ◽

Vol In Press (In Press) ◽

Cited By ~ 5

Author(s):

Ozlem Bostan Gayret ◽

Meltem Erol ◽

Hikmet Tekin Nacaroglu

Keyword(s):

Gastrointestinal Bleeding ◽

Henoch Schonlein Purpura ◽

Neutrophil Lymphocyte Ratio ◽

Lymphocyte Ratio ◽

Platelet Lymphocyte Ratio ◽

Relationship Of ◽

The Relationship ◽

Schonlein Purpura ◽

Henoch Schönlein Purpura

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The relationship between platelet–lymphocyte ratio, neutrophil–lymphocyte ratio, and survival in metastatic gastric cancer on firstline modified docetaxel and cisplatinum plus 5 Fluorourasil Regimen: A single institute experience

Saudi Journal of Gastroenterology ◽

10.4103/1319-3767.166207 ◽

2015 ◽

Vol 21 (5) ◽

pp. 320 ◽

Cited By ~ 8

Author(s):

Dogan Mutlu ◽

Tulay Eren ◽

Nuriye Ozdemir ◽

CanL Cigirgan ◽

Nurullah Zengin

Keyword(s):

Gastric Cancer ◽

Metastatic Gastric Cancer ◽

Neutrophil Lymphocyte Ratio ◽

Lymphocyte Ratio ◽

Platelet Lymphocyte Ratio ◽

The Relationship

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Platelet-lymphocyte ratio as a new predictor of in-hospital mortality in cardiac intensive care unit patients

Scientific Reports ◽

10.1038/s41598-021-02686-1 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Guangyao Zhai ◽

Jianlong Wang ◽

Yuyang Liu ◽

Yujie Zhou

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Cardiovascular Diseases ◽

Hospital Mortality ◽

Subgroup Analysis ◽

Cardiac Intensive Care Unit ◽

Lymphocyte Ratio ◽

Platelet Lymphocyte Ratio ◽

Cardiac Intensive Care ◽

The Relationship

AbstractIt has been discovered that both inflammation and platelet aggregation could cause crucial effect on the occurrence and development of cardiovascular diseases. As a combination of platelet and lymphocyte, platelet-lymphocyte ratio (PLR) was proved to be correlated with the severity as well as prognosis of cardiovascular diseases. Exploring the relationship between PLR and in-hospital mortality in cardiac intensive care unit (CICU) patients was the purpose of this study. PLR was calculated by dividing platelet count by lymphocyte count. All patients were grouped by PLR quartiles and the primary outcome was in-hospital mortality. The independent effect of PLR was determined by binary logistic regression analysis. The curve in line with overall trend was drawn by local weighted regression (Lowess). Subgroup analysis was used to determine the relationship between PLR and in-hospital mortality in different subgroups. We included 5577 CICU patients. As PLR quartiles increased, in-hospital mortality increased significantly (Quartile 4 vs. Quartile 1: 13.9 vs. 8.3, P < 0.001). After adjusting for confounding variables, PLR was proved to be independently associated with increased risk of in-hospital mortality (Quartile 4 vs. Quartile 1: OR 95% CI 1.55, 1.08–2.21, P = 0.016, P for trend < 0.001). The Lowess curves showed a positive relationship between PLR and in-hospital mortality. The subgroup analysis revealed that patients with low Acute Physiology and Chronic Health Evaluation IV (APACHE IV) or with less comorbidities had higher risk of mortality for PLR. Further, PLR quartiles had positive relation with length of CICU stay (Quartile 4 vs. Quartile 1: 2.7, 1.6–5.2 vs. 2.1, 1.3–3.9, P < 0.001), and the length of hospital stay (Quartile 4 vs. Quartile 1: 7.9, 4.6–13.1 vs. 5.8, 3.3–9.8, P < 0.001). PLR was independently associated with in-hospital mortality in CICU patients.

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