scholarly journals The Role of Antibacterial Metallic Elements in Simultaneously Improving the Corrosion Resistance and Antibacterial Activity of Magnesium Alloys

2021 ◽  
Vol 198 ◽  
pp. 109350
Author(s):  
Zhensheng Lin ◽  
Xiaoting Sun ◽  
Huazhe Yang
Author(s):  
Pramod Dhakal ◽  
Ankit a Achary ◽  
Vedamurthy Joshi

Bioenhancers are drug facilitator which do not show the typical drug activity but in combination to enhance the activity of other molecule in several way including increase the bioavailability of drug across the membrane, potentiating the drug molecules by conformational interaction, acting as receptor for drug molecules and making target cell more receptive to drugs and promote and increase the bioactivity or bioavailability or the uptake of drugs in combination therapy. The objective of the present study was to evaluate the antibacterial and activity of combination in Azadirachta indica extract with cow urine distillate and pepper extract against common pathogenic bacteria, a causative agent of watery diarrhea. It has been found that Indian indigenous cow urine and its distillate also possess bioenhancing ability. Bioenhancing role of cow urine distillate (CUD) and pepper extract was investigated on antibacterial activity of ethanol extract of Azadirachta indica. Antibacterial activity of ethanol extract neem alone and in combination with CUD and pepper extract were determined the ATCC strains against Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa and E-coli by cup plate diffusion method. Ethanol extract of neem has showed more effect on P. aeruginosa, E-coli than S. aureus and K. pneumonia with combination of CUD and pepper extract. CUD and pepper did not show any inhibition of test bacteria in low concentration. The antibacterial effect of combination of extract and CUD was higher than the inhibition caused by extract alone and is suggestive of the bioenhancing role of cow urine distillate and pepper. Moreover, inhibition of test bacteria was observed with less concentration of extract on combining with CUD


Author(s):  
Virginia Fuochi ◽  
Massimo Caruso ◽  
Rosalia Emma ◽  
Aldo Stivala ◽  
Riccardo Polosa ◽  
...  

Background: The key ingredients of e-cigarettes liquid are commonly propane-1,2-diol (also called propylene glycol) and propane-1,2,3-triol (vegetal glycerol) and their antimicrobial effects are already established. The nicotine and flavors which are often present in e-liquids can interfere with the growth of some microorganisms. Objective: The effect of the combining these elements in e-liquids is unknown. The aim of the study was to investigate the possible effects of these liquids on bacterial growth in the presence or absence of nicotine and flavors. Methods: Susceptibilities of pathogenic strains (Klebsiella pneumoniae, Staphylococcus aureus, Pseudomonas aeruginosa, Acinetobacter baumannii, Escherichia coli, Enterococcus faecalis and Sarcina lutea) were studied by means of a multidisciplinary approach. Cell viability and antioxidant assays were also evaluated. Results: All e-liquids investigated showed antibacterial activity against at least one pathogenic strain. A higher activity was correlated to the presence of flavors and nicotine. Discussion: In most cases the value of minimal bactericidal concentration is equal to the value of minimal inhibitory concentration showing that these substances have a bactericidal effect. This effect was observed in concentrations up to 6.25% v/v. Antioxidant activity was also correlated to presence of flavors. Over time, the viability assay in human epithelial lung A549 cells showed a dose-dependent inhibition of cell growth. Conclusion: Our results have shown that flavors considerably enhance the antibacterial activity of propane-1,2-diol and propane-1,2,3-triol. This study provides important evidence that should be taken into consideration in further investigative approaches, to clarify the different sensitivity of the various bacterial species to e-liquids, including the respiratory microbiota, to highlight the possible role of flavors and nicotine.


RSC Advances ◽  
2020 ◽  
Vol 10 (57) ◽  
pp. 34387-34395
Author(s):  
Le Van Sy ◽  
Phan Minh Quoc Binh ◽  
Bhajan Lal ◽  
Quy Bau Nguyen ◽  
Tran Van Hung ◽  
...  

The development of Mg–5Al–4Sn–xSr alloys with α-grain reduction, refined precipitates and pitting corrosion resistance by die casting.


Author(s):  
A. Prasad ◽  
Y. L. Chiu ◽  
I. P. Jones ◽  
S. S. Singh ◽  
N. N. Gosvami ◽  
...  

2020 ◽  
Vol 38 (3) ◽  
pp. 273-286 ◽  
Author(s):  
Cristina Garcia-Cabezon ◽  
Celia Garcia-Hernandez ◽  
Maria L. Rodriguez-Mendez ◽  
Gemma Herranz ◽  
Fernando Martin-Pedrosa

AbstractMicrostructural changes that result in relevant improvements in mechanical properties and electrochemical behavior can be induced using different sintering conditions of ASTM F75 cobalt alloys during their processing using powder metallurgy technique. It has been observed that the increase in carbon and nitrogen content improves corrosion resistance and mechanical properties as long as the precipitation of carbides and nitrides is avoided, thanks to the use of rapid cooling in water after the sintering stage. In addition, the reduction of the particle size of the powder improves hardness and resistance to corrosion in both acid medium with chlorides and phosphate-buffered medium that simulates the physiological conditions for its use as a biomaterial. These results lead to increased knowledge of the role of carbon and nitrogen content in the behavior displayed by the different alloys studied.


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