Glycosaminoglycans immobilized core-shell gold mesoporous silica nanoparticles for synergetic chemo-photothermal therapy of cancer cells

2022 ◽  
Vol 308 ◽  
pp. 131113
Author(s):  
Li Zhang ◽  
Hong Wang ◽  
Yiting Shen ◽  
Ying Sun ◽  
Juan Zhou ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Cancer Cells ◽  
Photothermal Therapy ◽  
Mesoporous Silica Nanoparticles ◽  
Core Shell

Mesoporous silica nanoparticles combined with MoS2 and FITC for fluorescence imaging and photothermal therapy of cancer cells

2020 ◽  
Vol 55 (31) ◽  
pp. 15263-15274
Author(s):  
Jie Wang ◽  
Zhifeng Li ◽  
Yamin Yin ◽  
Haisha Liu ◽  
Guohua Tang ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Cancer Cells ◽  
Fluorescence Imaging ◽  
Photothermal Therapy ◽  
Mesoporous Silica Nanoparticles

scholarly journals Targeted delivery of mesoporous silica nanoparticles loaded monastrol into cancer cells: an in vitro study

2017 ◽  
Vol 7 (8) ◽  
pp. 549-555 ◽  
Author(s):  
Huzaifa Hanif ◽  
Samina Nazir ◽  
Kehkashan Mazhar ◽  
Muhammad Waseem ◽  
Shazia Bano ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Cancer Cells ◽  
Targeted Delivery ◽  
Mesoporous Silica Nanoparticles ◽  
In Vitro Study ◽  
Vitro Study

AIE luminogen-functionalised mesoporous silica nanoparticles as nanotheranostic agents for imaging guided synergetic chemo-/photothermal therapy

2017 ◽  
Vol 4 (5) ◽  
pp. 833-839 ◽  
Author(s):  
Zhiying Fan ◽  
Li Ren ◽  
Wenjing Zhang ◽  
Dongdong Li ◽  
Guoqing Zhao ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Photothermal Therapy ◽  
Cell Imaging ◽  
Mesoporous Silica Nanoparticles

A novel AIE luminogen-functionalised nanotheranostic platform for cell imaging and simultaneous chemo- and photothermal therapies.

Gated Mesoporous Silica Nanoparticles for the Controlled Delivery of Drugs in Cancer Cells

Langmuir ◽  
2015 ◽  
Vol 31 (12) ◽  
pp. 3753-3762 ◽  
Author(s):  
Cristina Giménez ◽  
Cristina de la Torre ◽  
Mónica Gorbe ◽  
Elena Aznar ◽  
Félix Sancenón ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Cancer Cells ◽  
Mesoporous Silica Nanoparticles ◽  
Controlled Delivery

Fluorescent pH‐Responsive Mesoporous Silica Nanoparticles with Core‐Shell Feature as a Traceable Delivery Carrier for Ibuprofen

2020 ◽  
Vol 5 (20) ◽  
pp. 6123-6130
Author(s):  
Tingting Wei ◽  
Mengdi Sheng ◽  
Chang Liu ◽  
Jihong Sun ◽  
Xia Wu ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Core Shell ◽  
Ph Responsive

scholarly journals Large Pore Mesoporous Silica and Organosilica Nanoparticles for Pepstatin A Delivery in Breast Cancer Cells

Molecules ◽  
2019 ◽  
Vol 24 (2) ◽  
pp. 332 ◽  
Author(s):  
Saher Rahmani ◽  
Jelena Budimir ◽  
Mylene Sejalon ◽  
Morgane Daurat ◽  
Dina Aggad ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Cancer Cells ◽  
Cathepsin D ◽  
Breast Cancer Cells ◽  
Potent Inhibitor ◽  
Mesoporous Silica Nanoparticles ◽  
Sol Gel ◽  
Pepstatin A

(1) Background: Nanomedicine has recently emerged as a new area of research, particularly to fight cancer. In this field, we were interested in the vectorization of pepstatin A, a peptide which does not cross cell membranes, but which is a potent inhibitor of cathepsin D, an aspartic protease particularly overexpressed in breast cancer. (2) Methods: We studied two kinds of nanoparticles. For pepstatin A delivery, mesoporous silica nanoparticles with large pores (LPMSNs) and hollow organosilica nanoparticles (HOSNPs) obtained through the sol–gel procedure were used. The nanoparticles were loaded with pepstatin A, and then the nanoparticles were incubated with cancer cells. (3) Results: LPMSNs were monodisperse with 100 nm diameter. HOSNPs were more polydisperse with diameters below 100 nm. Good loading capacities were obtained for both types of nanoparticles. The nanoparticles were endocytosed in cancer cells, and HOSNPs led to the best results for cancer cell killing. (4) Conclusions: Mesoporous silica-based nanoparticles with large pores or cavities are promising for nanomedicine applications with peptides.

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