Inclusion of gold nanoparticles in meso-porous silicon for the SERS analysis of cell adhesion on nano-structured surfaces

The co-doping of graphene with Au nanoparticles and bis(trifluoromethanesulfonyl)-amide is employed for the first time to enhance the performance of graphene/porous Si solar cells.

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Evaluation of mammalian cell adhesion on surface-modified porous silicon

Biomaterials ◽

10.1016/j.biomaterials.2006.04.015 ◽

2006 ◽

Vol 27 (26) ◽

pp. 4538-4546 ◽

Cited By ~ 223

Author(s):

S LOW ◽

K WILLIAMS ◽

L CANHAM ◽

N VOELCKER

Keyword(s):

Cell Adhesion ◽

Porous Silicon ◽

Mammalian Cell ◽

Surface Modified

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Gold nanoclusters reductively deposited on porous silicon: morphology and electronic structures

Canadian Journal of Chemistry ◽

10.1139/v98-146 ◽

1998 ◽

Vol 76 (11) ◽

pp. 1707-1716 ◽

Cited By ~ 30

Author(s):

I Coulthard ◽

S Degen ◽

Y -J Zhu ◽

T K Sham

Keyword(s):

Gold Nanoparticles ◽

Porous Silicon ◽

Photoelectron Spectroscopy ◽

Gold Nanoclusters ◽

Gold Complex ◽

X Ray Diffraction ◽

Complex Ions ◽

X Ray ◽

Preparation Conditions ◽

P Type

Utilizing porous silicon as a reducing agent and a substrate, gold complex ions [AuCl4]- were reduced from aqueous solution to produce nanoparticles of gold upon the surface of porous silicon. Scanning electron microscopy (SEM) was utilized to study the morphology of the porous silicon layers and the deposits of gold nanoparticles. It is found that preparation conditions have a profound effect on the morphology of the deposits, especially on porous silicon prepared from a p-type wafer. The gold nanoparticles, varying from micrometric aggregates of clusters of the order of 10 nm, to a distribution of nearly spherical clusters of the order of 10 nm, to strings of ~10 nm were observed and compared to bulk gold metal using X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and X-ray absorption spectroscopy (XAS). These techniques confirm and complement the SEM findings. The potential for this reductive deposition technique is noted.Key words: gold nanostructures, reductive deposition, porous silicon, morphology, X-ray spectroscopy.

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Rapid and Highly Efficient Detection of Ultra-low Concentration of Penicillin G by Gold Nanoparticles/Porous Silicon SERS Active Substrate

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy ◽

10.1016/j.saa.2018.07.103 ◽

2019 ◽

Vol 206 ◽

pp. 31-36 ◽

Cited By ~ 20

Author(s):

Layla A. Wali ◽

Khulood K. Hasan ◽

Alwan M. Alwan

Keyword(s):

Gold Nanoparticles ◽

Porous Silicon ◽

Penicillin G ◽

Low Concentration ◽

Highly Efficient ◽

Efficient Detection ◽

Active Substrate ◽

Sers Active Substrate

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Decoration of Porous Silicon with Gold Nanoparticles via Layer-by-Layer Nanoassembly for Interferometric and Hybrid Photonic/Plasmonic (Bio)sensing

ACS Applied Materials & Interfaces ◽

10.1021/acsami.9b15737 ◽

2019 ◽

Vol 11 (46) ◽

pp. 43731-43740 ◽

Cited By ~ 7

Author(s):

Stefano Mariani ◽

Alessandro Paghi ◽

Antonino A. La Mattina ◽

Aline Debrassi ◽

Lars Dähne ◽

...

Keyword(s):

Gold Nanoparticles ◽

Porous Silicon ◽

Layer By Layer

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The Inhibitory Effects of Gold Nanoparticles on VEGF-A-Induced Cell Migration in Choroid-Retina Endothelial Cells

International Journal of Molecular Sciences ◽

10.3390/ijms21010109 ◽

2019 ◽

Vol 21 (1) ◽

pp. 109 ◽

Cited By ~ 4

Author(s):

Chi-Ming Chan ◽

Chien-Yu Hsiao ◽

Hsin-Ju Li ◽

Jia-You Fang ◽

Der-Chen Chang ◽

...

Keyword(s):

Gold Nanoparticles ◽

Endothelial Cells ◽

Cell Migration ◽

Cell Adhesion ◽

Age Related Macular Degeneration ◽

Adhesion Assay ◽

Dependent Manner ◽

Inhibitory Effects ◽

Viability Assay ◽

Age Related

Background: Vascular endothelial growth factor (VEGF) is upregulated by hypoxia and is a crucial stimulator for choroidal neovascularization (CNV) in age-related macular degeneration and pathologic myopia, as well as retinal neovascularization in proliferative diabetic retinopathy. Retinal and choroidal endothelial cells play key roles in the development of retinal and CNV, and subsequent fibrosis. At present, the effects of gold nanoparticles (AuNPs) on the VEGF-induced choroid-retina endothelial (RF/6A) cells are still unknown. In our study, we investigated the effects of AuNPs on RF/6A cell viabilities and cell adhesion to fibronectin, a major ECM protein of fibrovascular membrane. Furthermore, the inhibitory effects of AuNPs on RF/6A cell migration induced by VEGF and its signaling were studied. Methods: The cell viability assay was used to determine the viability of cells treated with AuNPs. The migration of RF/6A cells was assessed by the Transwell migration assay. The cell adhesion to fibronectin was examined by an adhesion assay. The VEGF-induced signaling pathways were determined by western blotting. Results: The 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) viability assay revealed no cytotoxicity of AuNPs on RF/6A cells. AuNPs inhibited VEGF-induced RF/6A cell migration in a concentration-dependent manner but showed no significant effects on RF/6A cell adhesion to fibronectin. Inhibitory effects of AuNPs on VEGF-induced Akt/eNOS were found. Conclusions: These results suggest that AuNPs are an effective inhibitor of VEGF-induced RF/6A cell migration through the Akt/eNOS pathways, but they have no effects on their cell viabilities and cell adhesion to fibronectin.

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