Highly sensitive manganese oxide/hexagonal boron nitride nanocomposite: An efficient electrocatalyst for the detection of anti-cancer drug flutamide

We outline a designer approach to endow widely available plain materials with topological properties by stacking them atop other nontopological materials. The approach is illustrated with a model system comprising graphene stacked atop hexagonal boron nitride. In this case, the Berry curvature of the electron Bloch bands is highly sensitive to the stacking configuration. As a result, electron topology can be controlled by crystal axes alignment, granting a practical route to designer topological materials. Berry curvature manifests itself in transport via the valley Hall effect and long-range chargeless valley currents. The nonlocal electrical response mediated by such currents provides diagnostics for band topology.

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Highly sensitive detection of anti-cancer drug based on bimetallic reduced graphene oxide nanocomposite

Chemosphere ◽

10.1016/j.chemosphere.2021.132281 ◽

2021 ◽

pp. 132281

Author(s):

Bathinapatla Sravani ◽

S. Kiranmai ◽

G. Rajasekhar Reddy ◽

Jong Pil Park ◽

Y. Veera Manohara Reddy ◽

...

Keyword(s):

Graphene Oxide ◽

Reduced Graphene Oxide ◽

Sensitive Detection ◽

Cancer Drug ◽

Reduced Graphene ◽

Highly Sensitive ◽

Anti Cancer ◽

Highly Sensitive Detection

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Theoretical demonstration of the potentiality of boron nitride nanotubes to encapsulate anticancer molecule

Physical Chemistry Chemical Physics ◽

10.1039/c5cp05148g ◽

2015 ◽

Vol 17 (44) ◽

pp. 30057-30064 ◽

Cited By ~ 12

Author(s):

Mohammed El Khalifi ◽

Eric Duverger ◽

Tijani Gharbi ◽

Hatem Boulahdour ◽

Fabien Picaud

Keyword(s):

Boron Nitride ◽

Boron Nitride Nanotubes ◽

Cancer Drug ◽

Release Time ◽

Anti Cancer

The encapsulation of carboplatin anti-cancer drug is energetically favored inside small hydrated boron nitride nanotubes with a long release time.

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Amino acid functionalized boron nitride nanotubes as an effective nanocarriers for Thiotepa anti-cancer drug delivery

Journal of Molecular Liquids ◽

10.1016/j.molliq.2021.117967 ◽

2021 ◽

pp. 117967

Author(s):

Yan Cao ◽

M.A. El-Shorbagy ◽

Kamal Sharma ◽

Sagr Alamri ◽

Ali A. Rajhi ◽

...

Keyword(s):

Drug Delivery ◽

Amino Acid ◽

Boron Nitride ◽

Boron Nitride Nanotubes ◽

Cancer Drug ◽

Anti Cancer ◽

Cancer Drug Delivery

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Hexagonal Boron Nitride Functionalized with Au Nanoparticles—Properties and Potential Biological Applications

Nanomaterials ◽

10.3390/nano8080605 ◽

2018 ◽

Vol 8 (8) ◽

pp. 605 ◽

Cited By ~ 15

Author(s):

Magdalena Jedrzejczak-Silicka ◽

Martyna Trukawka ◽

Mateusz Dudziak ◽

Katarzyna Piotrowska ◽

Ewa Mijowska

Keyword(s):

Gold Nanoparticles ◽

Boron Nitride ◽

Hexagonal Boron Nitride ◽

Drug Carrier ◽

Cancer Drug ◽

Mitochondrial Activity ◽

Uptake Assay ◽

White Graphene ◽

Cancer Drug Delivery ◽

Mcf 7

Hexagonal boron nitride is often referred to as white graphene. This is a 2D layered material, with a structure similar to graphene. It has gained many applications in cosmetics, dental cements, ceramics etc. Hexagonal boron nitride is also used in medicine, as a drug carrier similar as graphene or graphene oxide. Here we report that this material can be exfoliated in two steps: chemical treatment (via modified Hummers method) followed by the sonication treatment. Afterwards, the surface of the obtained material can be efficiently functionalized with gold nanoparticles. The mitochondrial activity was not affected in L929 and MCF-7 cell line cultures during 24-h incubation, whereas longer incubation (for 48, and 72 h) with this nanocomposite affected the cellular metabolism. Lysosome functionality, analyzed using the NR uptake assay, was also reduced in both cell lines. Interestingly, the rate of MCF-7 cell proliferation was reduced when exposed to h-BN loaded with gold nanoparticles. It is believed that h-BN nanocomposite with gold nanoparticles is an attractive material for cancer drug delivery and photodynamic therapy in cancer killing.

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