Characterisation of pre-weakening effect on ores by high voltage electrical pulses based on single-particle tests

2013 ◽  
Vol 50-51 ◽  
pp. 69-76 ◽  
Author(s):  
Fengnian Shi ◽  
Weiran Zuo ◽  
Emmy Manlapig
Keyword(s):  
High Voltage ◽  
Single Particle ◽  
Electrical Pulses

Design of an Irreversible Electroporation System for Clinical Use

2007 ◽  
Vol 6 (4) ◽  
pp. 313-320 ◽  
Author(s):  
Claudio Bertacchini ◽  
Pier Mauro Margotti ◽  
Enrico Bergamini ◽  
Andrea Lodi ◽  
Mattia Ronchetti ◽  
...  
Keyword(s):  
High Voltage ◽  
Traditional Approach ◽  
Irreversible Electroporation ◽  
Target Volume ◽  
High Energy ◽  
Target Tissue ◽  
Clinical Use ◽  
Safety Issues ◽  
Electrical Pulses ◽  
Effective Delivery

Irreversible electroporation is an ablation modality in which microseconds, high-voltage electrical pulses are applied to induce cell necrosis in a target tissue. To perform irreversible electroporation it is necessary to use a medical device specifically designed for this use. The design of an irreversible electroporation system is a complex task in which the effective delivery of high energy pulses and the safety of the patient and operator are equally important. Pulses of up to 3000 V of amplitude and 50 A of current need to be generated to irreversibly electroporate a target volume of approximately 50 to 70 cm3 with as many as six separate electrodes; therefore, a traditional approach based on high voltage amplifiers becomes hard to implement. In this paper, we present the process that led to the first irreversible electroporator capable of such performances approved for clinical use. The main design choices and its architecture are outlined. Safety issues are also explained along with the solutions adopted.

Effect of high voltage electrical pulses on subcutaneous glioma tumours on rats

1998 ◽  
Vol 47 (1) ◽  
pp. 163-166
Author(s):  
Per E. Engström ◽  
Bertil R.R. Persson ◽  
Leif G. Salford
Keyword(s):  
High Voltage ◽  
Electrical Pulses

scholarly journals An Enhanced Electroporator Design for Pulse Generation

2021 ◽  
Vol 11 (5) ◽  
pp. 7610-7614
Author(s):  
S. Pachamuthu ◽  
D. Najumnissa ◽  
K. Sankaranarayanan ◽  
R. P. Ramachandran
Keyword(s):  
High Voltage ◽  
Pulse Generation ◽  
Voltage Source ◽  
Turn On ◽  
Main System ◽  
Electrical Pulses ◽  
High Voltage Source ◽  
Source Block

An electroporator is an instrument used for delivering electrical pulses to a tumor. In this work, an electroporator consisting of three main system blocks, namely High Voltage (HV) source, nanosecond (ns) switching, and pulse generation, was designed, developed, and evaluated to generate high voltage ns pulses to treat tumors. The high-voltage source block was used to convert the 9.6V DC from the battery to a variable HV output and store this charge for later use. The ns switching block contained a MOSFET-based low-side switch which applies short ns pulses to the load. The pulse generation block generates short ns pulses and supplies the adequate current to turn on the MOSFET at a quicker rate aiding the application of these pulses to the load. This process was simulated using PSpice software and the results are presented.

Liberation of minerals by high-voltage electrical pulses

1999 ◽  
Vol 104 (1) ◽  
pp. 37-49 ◽  
Author(s):  
U Andres ◽  
J Jirestig ◽  
I Timoshkin
Keyword(s):  
High Voltage ◽  
Electrical Pulses

Effect of moisture content on structural evolution characteristics of bituminous coal subjected to high-voltage electrical pulses

Fuel ◽  
2019 ◽  
Vol 241 ◽  
pp. 571-578 ◽  
Author(s):  
Fazhi Yan ◽  
Jiang Xu ◽  
Baiquan Lin ◽  
Shoujian Peng ◽  
Quanle Zou ◽  
...  
Keyword(s):  
Moisture Content ◽  
High Voltage ◽  
Bituminous Coal ◽  
Structural Evolution ◽  
Evolution Characteristics ◽  
Electrical Pulses ◽  
Effect Of Moisture
Sign in / Sign up

Export Citation Format

Share Document