Effect of support surface chemistry on lipase adsorption and activity

Purpose. To analyze whether a viscoelastic mattress support surface can reduce the incidence of stage 2 pressure injuries compared to a standard hospital mattress with pyramidal overlay in critically ill patients. Method. A randomized clinical trial with intention-to-treat analysis was carried out recruiting patients with Braden scale ≤14 on intensive care unit admission from April 2016 to April 2017. Patients were allocated into two groups: intervention group (viscoelastic mattress) and control group (standard mattress with pyramidal overlay). The level of significance adopted was 5%. Results. A total of 62 patients were included in the study. There was a predominance of males (53%) and the mean age was 67.9 (SD 18.8) years. There were no differences in clinical or severity characteristics between the patients in the control group and the intervention group. Pressure injuries occurred in 35 patients, with a median time of 7 days (ITQ 4–10) from admission. The frequency of pressure injuries was higher in the control group (80.6%) compared to the intervention group (32.2%; p<0.001). Conclusions. Viscoelastic support surfaces reduced the incidence of pressure injuries in moderate or higher risk critically ill patients when compared to pyramidal support surfaces.

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Selective Oxidation of Glycerol Catalyzed by Rh/Activated Carbon: Importance of Support Surface Chemistry

Catalysis Letters ◽

10.1007/s10562-010-0515-9 ◽

2010 ◽

Vol 141 (3) ◽

pp. 420-431 ◽

Cited By ~ 44

Author(s):

Elodie G. Rodrigues ◽

Sónia A. C. Carabineiro ◽

Xiaowei Chen ◽

Juan J. Delgado ◽

José L. Figueiredo ◽

...

Keyword(s):

Activated Carbon ◽

Surface Chemistry ◽

Selective Oxidation ◽

Support Surface

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EFFECT OF SUPPORT SURFACE ON PRESSURE ULCER HEALING RATE*

Journal of Wound Ostomy and Continence Nursing ◽

10.1097/00152192-200405001-00004 ◽

2004 ◽

Vol 31 (Supplement) ◽

pp. S2

Author(s):

Rachel Ochs ◽

Susan Horn ◽

Randall Smout ◽

Lia van Rijswijk

Keyword(s):

Pressure Ulcer ◽

Ulcer Healing ◽

Healing Rate ◽

Support Surface ◽

Ulcer Healing Rate ◽

Effect Of Support

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Lipase adsorption on different nanomaterials: a multi-scale simulation study

Physical Chemistry Chemical Physics ◽

10.1039/c4cp04696j ◽

2015 ◽

Vol 17 (2) ◽

pp. 840-850 ◽

Cited By ~ 51

Author(s):

Daohui Zhao ◽

Chunwang Peng ◽

Jian Zhou

Keyword(s):

Surface Chemistry ◽

Simulation Study ◽

P Adsorption ◽

Multi Scale ◽

Lipase Adsorption

Adsorption orientations of lipase on different nanomaterials with different surface chemistry.

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Lipase Immobilization on Functional Group Controlled Surfaces

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.441.452 ◽

2012 ◽

Vol 441 ◽

pp. 452-456 ◽

Cited By ~ 1

Author(s):

Peng Ye ◽

Xin Ping Wang ◽

Zhu Ping Han ◽

Jie Yang ◽

Rong Bing Wan

Keyword(s):

Molecular Weight ◽

Surface Chemistry ◽

Functional Group ◽

Immobilized Lipase ◽

Lipase Immobilization ◽

Small Molecular Weight ◽

Group Density ◽

Model Support ◽

Lipase Adsorption ◽

Effect Of Surface

A simple means was demonstrated to control the functional group on surface and use this surface as a model support to investigate the effect of surface chemistry on lipase adsorption and its activity. It was based on mixing polystyrene (PS) solution with small molecular weight functional group-terminated polystyrenes (PS-Fs, functional groups such as-CH3, -CF3, -NH2, -COOH and-OH) and casting them on glass plates to fabricate the functional group controlled surfaces. The amount of adsorbed lipase on the surface with similar functional group density was-CH3> PS > -CF3> -NH2> -COOH > -OH. The activity retention of the immobilized lipase was-OH > -NH2> -COOH > -CF3> -CH3> PS.

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