Loading and release of anticancer drug from phosphorene as a template material with high efficient carrier: From vacuum to cell membrane

2019 ◽  
Vol 291 ◽  
pp. 111346 ◽  
Author(s):  
Hassan Hashemzadeh ◽  
Heidar Raissi
2016 ◽  
Vol 18 (36) ◽  
pp. 24994-25001 ◽  
Author(s):  
M. El Khalifi ◽  
J. Bentin ◽  
E. Duverger ◽  
T. Gharbi ◽  
H. Boulahdour ◽  
...  

Payload delivery of anticancer cisplatin molecules assisted by the cell membrane lipid.


RSC Advances ◽  
2015 ◽  
Vol 5 (59) ◽  
pp. 47629-47639 ◽  
Author(s):  
Lan Bai ◽  
Fei Song ◽  
Xiao-hui Wang ◽  
Jiang-yong-quan Cao ◽  
Xue Han ◽  
...  

A ligand–metal-drug coordination architecture is exploited to construct polymeric micelles with the high efficient loading and pH-triggered release of anticancer drug.


2020 ◽  
Vol 196 ◽  
pp. 111357
Author(s):  
Elsa M. Materon ◽  
Gustavo F. Nascimento ◽  
Flavio M. Shimizu ◽  
Amanda S. Câmara ◽  
Bianca Sandrino ◽  
...  

Author(s):  
M. Ashraf ◽  
L. Landa ◽  
L. Nimmo ◽  
C. M. Bloor

Following coronary artery occlusion, the myocardial cells lose intracellular enzymes that appear in the serum 3 hrs later. By this time the cells in the ischemic zone have already undergone irreversible changes, and the cell membrane permeability is variably altered in the ischemic cells. At certain stages or intervals the cell membrane changes, allowing release of cytoplasmic enzymes. To correlate the changes in cell membrane permeability with the enzyme release, we used colloidal lanthanum (La+++) as a histological permeability marker in the isolated perfused hearts. The hearts removed from sprague-Dawley rats were perfused with standard Krebs-Henseleit medium gassed with 95% O2 + 5% CO2. The hypoxic medium contained mannitol instead of dextrose and was bubbled with 95% N2 + 5% CO2. The final osmolarity of the medium was 295 M osmol, pH 7. 4.


Author(s):  
J. J. Paulin

Movement in epimastigote and trypomastigote stages of trypanosomes is accomplished by planar sinusoidal beating of the anteriorly directed flagellum and associated undulating membrane. The flagellum emerges from a bottle-shaped depression, the flagellar pocket, opening on the lateral surface of the cell. The limiting cell membrane envelopes not only the body of the trypanosome but is continuous with and insheathes the flagellar axoneme forming the undulating membrane. In some species a paraxial rod parallels the axoneme from its point of emergence at the flagellar pocket and is an integral component of the undulating membrane. A portion of the flagellum may extend beyond the anterior apex of the cell as a free flagellum; the length is variable in different species of trypanosomes.


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