Do physico-chemical properties of silver nanoparticles decide their interaction with biological media and bactericidal action? A review

2018 ◽  
Vol 90 ◽  
pp. 739-749 ◽  
Author(s):  
Vikram Pareek ◽  
Rinki Gupta ◽  
Jitendra Panwar
Keyword(s):  
Silver Nanoparticles ◽  
Chemical Properties ◽  
Bactericidal Action ◽  
Biological Media ◽  
Physico Chemical

scholarly journals Silver Nanoparticles Stabilized with Phosphorus-Containing Heterocyclic Surfactants: Synthesis, Physico-Chemical Properties, and Biological Activity Determination

Nanomaterials ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1883
Author(s):  
Martin Pisárčik ◽  
Miloš Lukáč ◽  
Josef Jampílek ◽  
František Bilka ◽  
Andrea Bilková ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Biological Activity ◽  
Zeta Potential ◽  
Chain Length ◽  
Alkyl Chain ◽  
Chemical Properties ◽  
Alkyl Chain Length ◽  
Microbial Pathogens ◽  
Physico Chemical ◽  
Phosphorus Containing

Phosphorus-containing heterocyclic cationic surfactants alkyldimethylphenylphospholium bromides with the alkyl chain length 14 to 18 carbon atoms were used for the stabilization of silver nanodispersions. Zeta potential of silver nanodispersions ranges from +35 to +70 mV, which indicates the formation of stable silver nanoparticles (AgNPs). Long-chain heptadecyl and octadecyl homologs of the surfactants series provided the most intensive stabilizing effect to AgNPs, resulting in high positive zeta potential values and smaller diameter of AgNPs in the range 50–60 nm. A comparison with non-heterocyclic alkyltrimethylphosphonium surfactants of the same alkyl chain length showed better stability and more positive zeta potential values for silver nanodispersions stabilized with heterocyclic phospholium surfactants. Investigations of biological activity of phospholium-capped AgNPs are represented by the studies of antimicrobial activity and cytotoxicity. While cytotoxicity results revealed an increased level of HepG2 cell growth inhibition as compared with the cytotoxicity level of silver-free surfactant solutions, no enhanced antimicrobial action of phospholium-capped AgNPs against microbial pathogens was observed. The comparison of cytotoxicity of AgNPs stabilized with various non-heterocyclic ammonium and phosphonium surfactants shows that AgNPs capped with heterocyclic alkyldimethylphenylphospholium and non-heterocyclic triphenyl-substituted phosphonium surfactants have the highest cytotoxicity among silver nanodispersions stabilized by the series of ammonium and phosphonium surfactants.

scholarly journals Coating Matters: Review on Colloidal Stability of Nanoparticles with Biocompatible Coatings in Biological Media, Living Cells and Organisms

2018 ◽  
Vol 25 (35) ◽  
pp. 4553-4586 ◽  
Author(s):  
Jonas Schubert ◽  
Munish Chanana
Keyword(s):  
Colloidal Stability ◽  
Biological Fluids ◽  
Chemical Properties ◽  
Coating Material ◽  
Living Systems ◽  
Biological Media ◽  
Coating Materials ◽  
Physico Chemical ◽  
Environment Temperature ◽  
To Come

Within the last two decades, the field of nanomedicine has not developed as successfully as has widely been hoped for. The main reason for this is the immense complexity of the biological systems, including the physico-chemical properties of the biological fluids as well as the biochemistry and the physiology of living systems. The nanoparticles’ physicochemical properties are also highly important. These differ profoundly from those of freshly synthesized particles when applied in biological/living systems as recent research in this field reveals. The physico-chemical properties of nanoparticles are predefined by their structural and functional design (core and coating material) and are highly affected by their interaction with the environment (temperature, pH, salt, proteins, cells). Since the coating material is the first part of the particle to come in contact with the environment, it does not only provide biocompatibility, but also defines the behavior (e.g. colloidal stability) and the fate (degradation, excretion, accumulation) of nanoparticles in the living systems. Hence, the coating matters, particularly for a nanoparticle system for biomedical applications, which has to fulfill its task in the complex environment of biological fluids, cells and organisms. In this review, we evaluate the performance of different coating materials for nanoparticles concerning their ability to provide colloidal stability in biological media and living systems.

scholarly journals Nanoparticle colloidal stability in cell culture media and impact on cellular interactions

2015 ◽  
Vol 44 (17) ◽  
pp. 6287-6305 ◽  
Author(s):  
Thomas L. Moore ◽  
Laura Rodriguez-Lorenzo ◽  
Vera Hirsch ◽  
Sandor Balog ◽  
Dominic Urban ◽  
...  
Keyword(s):  
Cell Culture ◽  
Colloidal Stability ◽  
Culture Media ◽  
Chemical Properties ◽  
Cellular Interactions ◽  
Biological Media ◽  
Cell Culture Media ◽  
Biological Fate ◽  
Physico Chemical ◽  
Shed Light

This review discusses nanoparticle colloidal stability in biological media in an attempt to shed light on the difficulty correlating nanoparticle physico-chemical properties and biological fate.

Autoclave-assisted green synthesis of silver nanoparticles using A. fumigatus mycelia extract and the evaluation of their physico-chemical properties and antibacterial activity

2018 ◽  
Vol 7 (3) ◽  
pp. 217-224 ◽  
Author(s):  
Sarah Ghanbari ◽  
Hamideh Vaghari ◽  
Zahra Sayyar ◽  
Mohammad Adibpour ◽  
Hoda Jafarizadeh-Malmiri
Keyword(s):  
Particle Size ◽  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Chemical Properties ◽  
Heating Time ◽  
Gram Negative Bacteria ◽  
Synthesis Conditions ◽  
High Antibacterial Activity ◽  
Physico Chemical ◽  
Ft Ir

Abstract Silver nanoparticles (AgNPs) were synthesized using Aspergillus fumigatus (A. fumigatus) mycelia extract via the hydrothermal method. The main reducing and stabilizing groups and components of A. fumigatus extract, such as amine, hydroxyl, amid, protein, enzymes, and cell saccharide compounds, were identified by Fourier transform infrared (FT-IR). Central composition design was used to plan the experiments, and response surface methodology was applied to evaluate of the effects of independent variables, including the amount of the prepared extract (5–7 ml) and heating time (10–20 min) at 121°C and 1.5 bar), on the particle size of the synthesized AgNPs, as manifested in broad emission peak (λmax). More stable and spherical monodispersed AgNPs, with mean particle size, polydispersity index (PDI) value, and maximum ζ potential value of 23 nm, 0.270, and +35.3 mV, respectively, were obtained at the optimal synthesis conditions using 7 ml of A. fumigatus extract and heating time of 20 min. The synthesized AgNPs indicated high antibacterial activity against both Gram-positive and Gram-negative bacteria.

scholarly journals Bactericidal Effect of Cotton Fabric Treated with Polymer Solution Containing Silver Nanoparticles of Different Sizes and Shapes

2020 ◽  
Vol 32 (6) ◽  
pp. 1335-1342
Author(s):  
Kh. E. Yunusov ◽  
A.A. Sarymsakov ◽  
S.V. Mullajonova ◽  
F.M. Turakulov ◽  
S. Sh. Rashidova
Keyword(s):  
Silver Nanoparticles ◽  
Chemical Properties ◽  
Bactericidal Effect ◽  
Cotton Fabrics ◽  
Sodium Carboxymethylcellulose ◽  
Force Microscopy ◽  
Transmission Electron ◽  
Physico Chemical ◽  
Vis Spectroscopy ◽  
Silver Nitrate Concentration

Stable silver nanoparticles in solutions of sodium-carboxymethylcellulose (Na-CMC) were synthesized and their structure and physico-chemical properties were evaluated. The form and sizes of silver nanoparticles formed in solutions of CMC and cotton fabrics were studied using UV-VIS spectroscopy, atomic force microscopy and transmission electron microscopy methods. It was found that silver nitrate concentration increase in sodium carboxymethylcellulose solutions, as well as photoirradiation of the hydrogel lead to the changes of the silver nanoparticles size and shape. Investigations have also shown that spherical silver nanoparticles with sizes of 5-35 nm and content of 0.0086 mass% in cotton fabrics possess high bactericidal activity. Stabilization of silver nanoparticles has preserved bactericidal and bacteriostatic activities during the washing of cotton fabrics and textiles on their base.

Anti-Cancer and Antibacterial Effects of Terfezia boudieri-Derived Silver Nanoparticles

2020 ◽  
Vol 23 ◽  
Author(s):  
Hashem Yaghoubi ◽  
Amin Izadpanah ◽  
Shahla Nedaei ◽  
Hossein Akbari ◽  
Elmira Mikaeili Agah ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Chemical Properties ◽  
Chemotherapeutic Agents ◽  
Dependent Manner ◽  
Biomedical Sciences ◽  
Synthesis Time ◽  
Physico Chemical ◽  
Anti Cancer ◽  
Bactericidal Effects ◽  
Terfezia Boudieri

Background: The use of nanoparticles has markedly increased in biomedical sciences. The silver nanoparticles (AgNPs) have been investigated for their applicability to deliver chemotherapeutic agents in cancer treatment. However, the existing chemical and physical methods of synthesizing AgNPs are considered inefficient and expensive, and are fraught with toxicity. Objective: Natural products have emerged as viable candidates for nanoparticle production, including the use of Terfezia boudieri (T. boudieri), a member of the edible truffle family. Accordingly, our goal was to synthesize AgNPs using the aqueous extract of T. boudieri (green synthesized AgNPs). Since certain infectious agents are linked to cancer, we further investigated their potential as anti-cancer and antibacterial agents. Methods: The physico-chemical properties of green synthesized AgNPs were analyzed by UV-Vis, FT-IR, XRD, SEM and TEM. In addition, their potential to inhibit cancer cell (MCF-7 and AGS) proliferation as well as the growth of infectious bacteria were investigated. Synthesis of AgNPs was confirmed by the presence of an absorption peak at 450nm by spectroscopy. Results: The size of nanoparticles ranged between 20-30nm and exerted significant cytotoxicity and bactericidal effects in a concentration and time dependent manner compared to T. boudieri extract alone. Interestingly, synthesis of smaller AgNPs correlated with longer synthesis time and enhanced cytotoxic and bactericidal properties. Conclusion: This study shows that synthesis of smaller AgNPs correlated with longer synthesis time and enhanced cytotoxic and anti-bacterial effects.

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