Corrigendum to “Effects of midfoot joint mobilization on ankle-foot morphology and function following acute ankle sprain. A crossover clinical trial” [Musculoskel. Sci. Pract. 46 (2020) 102130]

ABSTRACT Factors that influence viability and function of cryopreserved peripheral blood mononuclear cells (PBMC) were identified on 54 samples from 27 AIDS Clinical Trial Units. PBMC viability ranged from 1 to 96% with a median of 70%, was higher in laboratories with experienced staff, and was not significantly associated with CD4 cell number. Function of cryopreserved PBMC, measured by lymphocyte proliferation, was associated with viability. Preparations with viability greater than or equal to 70% had consistent proliferative responses and were suitable for functional analyses.

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Effect of empagliflozin on myocardial structure and function in patients with type 2 diabetes at high cardiovascular risk: the SIMPLE randomized clinical trial

The International Journal of Cardiovascular Imaging ◽

10.1007/s10554-021-02443-5 ◽

2021 ◽

Author(s):

Mads Ersbøll ◽

Mikkel Jürgens ◽

Philip Hasbak ◽

Andreas Kjær ◽

Emil Wolsk ◽

...

Keyword(s):

Type 2 Diabetes ◽

Clinical Trial ◽

Cardiovascular Risk ◽

Randomized Clinical Trial ◽

Structure And Function ◽

High Cardiovascular Risk ◽

Myocardial Structure ◽

And Function

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Effectiveness of Acromioclavicular Joint Mobilization and Physical Therapy vs Physical Therapy Alone in Patients with Frozen Shoulder: A Randomized Clinical Trial

10.21203/rs.3.rs-548390/v1 ◽

2021 ◽

Author(s):

Mohammad Rahbar ◽

Sepideh Ranjbar Kiyakalayeh ◽

Bina Eftekharsadat ◽

Behzad Izadseresht ◽

Neda Dolatkhah

Keyword(s):

Clinical Trial ◽

Physical Therapy ◽

Randomized Clinical Trial ◽

Shoulder Pain ◽

Acromioclavicular Joint ◽

Frozen Shoulder ◽

Secondary Outcome ◽

Control Group ◽

Joint Mobilization ◽

Active Abduction

Abstract Background: Frozen shoulder (FS) is a prevalent musculoskeletal condition characterized by an often prolonged pain, disability and limited active and passive range of motion (ROM), however its management remains challenging yet. The objective of this trial was to compare the efficacy of acromioclavicular joint mobilization and physical therapy versus physical therapy in treatment of FS.Methods: In this single-blind randomized clinical trial, patients with diagnosis of FS were randomly allocated into mobilization + physical therapy (n=28) as experiment group, and physical therapy (n=28) as control group in two outpatient clinics of Tabriz University of Medical Sciences, Iran. The primary outcomes were self-reported shoulder pain-related disability measured by the Shoulder Pain and Disability Index (SPADI) questionnaire and goniometric assessment of shoulder ROM. The secondary outcome was the Visual Analogue Scale (VAS). Measures were performed at the baseline, immediately and one month after beginning the treatments.Results: Totally 51 patients with 25.73 ± 6.88 years old of age completed the study and their data were analyzed. VAS, SPADI, pain and disability improved more significantly in experiment group compared to control group immediately [-4.63 (-5.58- -3.67) vs. -2.22 (-2.96- -1.47), p<0.001; -23.08 (-28.63- -17.53) vs. -13.04 (-17.93- -8.16), p=0.008; -26.00 (-31.71- -20.29) vs. -16.35 (-23.39- -9.31), p=0.034 and -21.25 (-29.11- -13.39) vs. -10.98 (-17.53- -4.43), p=0.042, respectively] and one month after beginning of treatment [-5.58 (-6.45- -4.72) vs. -3.61 (-4.60- -2.62), p<0.001; -33.43 (-40.85- -26.01) vs. -20.03 (-26.00- -14.07), p=0.001; --42.83 (-49.09- -36.57) vs. -25.57 (-33.92- -17.21), p<0.001 and -27.55 (-36.19- -15.94) vs. -16.58 (-24.48- -8.67), p=0.041, respectively]. Active abduction ROM was also improved more significantly immediately after treatment in experiment group compared to control group [25.83 (11.45- 40.13) vs. 10.17 (1.02- 19.15), p=0.025], however there were no significant differences between two groups concerning other measured ROMs immediately and one month after treatment (all p>0.05). Conclusions: Acromioclavicular mobilization along with conventional physical therapy was more efficient in decreasing pain and disability and improving active abduction ROM compared to physical therapy in patients with FS. These findings would suggest a new therapeutic method for shoulder disorders with pain and disability.Trial registrationwww.irct.ir, IRCT20100605004104N7, registered 06.01.2019 (https://www.irct.ir/trial/35900)

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Multidisciplinary Evaluation of Pacifier Removal on Oro-Dentofacial Structures: A Controlled Clinical Trial

Frontiers in Pediatrics ◽

10.3389/fped.2021.703695 ◽

2021 ◽

Vol 9 ◽

Author(s):

Kelly Guedes de Oliveira Scudine ◽

Camila Nobre de Freitas ◽

Kizzy Silva Germano Nascimento de Moraes ◽

Silvana Bommarito ◽

Rosana de Fátima Possobon ◽

...

Keyword(s):

Clinical Trial ◽

Mixed Model ◽

Control Group ◽

Controlled Clinical Trial ◽

Functional Changes ◽

Mixed Model Anova ◽

And Function ◽

Clinical Trials Registry ◽

Facial Anthropometry ◽

Over Time

It is well recognized that pacifier habit leads to occlusal and orofacial functional changes in children. However, the effects of the interruption of prolonged pacifier habit on the development of the dento-facial complex has not yet been fully characterized. Thus, the aim of this study was to investigate the influence of pacifier removal on aspects of oro-dentofacial morphology and function in preschool children. For that, a pacifier group (n = 28) and a control group (n = 32) of 4-year-old children with and without pacifier habit, respectively, were followed up by a group of dentists and speech therapists at baseline, 6 and 12 months after habit removal. Bite force and lip pressure were assessed using digital systems, and the evaluation of breathing and speech functions was performed using validated protocols, together with the measurements of dental casts and facial anthropometry. The Two-way mixed model ANOVA was used in data analysis. After 12 months, a decrease in malocclusion frequency was observed in pacifier group. Additionally, a change over time was observed in facial, intermolar and palate depth measurements, as well in bite and lip forces and speech function scores, increasing in both groups (p < 0.01). The upper and lower intercanine widths and breathing scores differed between groups at baseline and changed over time reducing the differences. The presence of speech distortions was more frequent in the pacifier group at baseline and decreased over time (p < 0.05). The interruption of pacifier habit improved the maxillary and mandibular intercanine widths, as well as the breathing and speech functions, overcoming the oro-dentofacial changes found.Trial Registration: This clinical trial was registered in the Brazilian Clinical Trials Registry (ReBEC; http://www.ensaiosclinicos.gov.br/), protocol no. RBR-728MJ2.

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Effect of Temporomandibular Joint Mobilization on Neck Pain and Function in Patients with Chronic Non-Specific Neck Pain

Reabilitacijos mokslai slauga kineziterapija ergoterapija ◽

10.33607/rmske.v2i19.759 ◽

2019 ◽

Vol 2 (19) ◽

Author(s):

Edgaras Lapinskas ◽

Janina Stirbytė

Keyword(s):

Neck Pain ◽

Temporomandibular Joint ◽

Chronic Neck Pain ◽

Flexor Muscle ◽

Joint Mobilization ◽

Movement Characteristics ◽

Neck Function ◽

Before And After ◽

And Function

Background. Neck pain is a common problem, and it includes 30% of 25–29 year olds. The percentage of people over 45 years of age has risen to 50% (Knight and Draper, 2012). Long-term muscle imbalance disrupts body biomechanics. Due to long-lasting pain, the quality of work may decrease, rest can get worse, and mood may change. Purpose. To determine the eﬀect of temporomandibular joint mobilization for neck pain and function in patients who suﬀer chronic non-specifc neck pain. Methods. The study involved six people with non-specifc chronic neck pain, who were divided into two groups: exercises, and the second group – exercises and mobilization of temporomandibular joint. At the beginning and end of the study, we performed the following tests: deep neck ﬂexor endurance test, visual analogue scale (VAS), goniometry, the amplitude of the temporomandibular joint. Results. In the group of exercises, the pain score after treatment decreased (before – 67 ± 28, after – 14 ± 16.5) the strength and endurance of the deep neck ﬂexor muscle improved (before – 13.7 ± 2.5 s, after – 28.7 ± 6.4 s). The amplitude of all neck movements was improved (p < 0.05), comparing them before and after physiotherapy. The amplitude of the temporomandibular joint improved the movement characteristics: depression, lateral excursions to left and right, protrusion (p < 0.05). Conclusions. Comparing the results after applying diﬀerent methods of physiotherapy, intensity of pain and neck function parameters did not show significant diﬀerences.Keywords: temporomandibular joint, nonspecifc neck pain, mobilization.

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