Cortical signature related to psychometric properties of pain vigilance in healthy individuals: a voxel-based morphometric study

2022 ◽  
pp. 136445
Author(s):  
Kazuaki Nagasaka ◽  
Naofumi Otsuru ◽  
Rui Sato ◽  
Hiraku Watanabe ◽  
Noriko Sakurai ◽  
...  
Keyword(s):  
Psychometric Properties ◽  
Morphometric Study ◽  
Healthy Individuals

Cortical Signature Related to Psychometric Properties of Pain Vigilance in Healthy Individuals: A Voxel-Based Morphometric Study

2021 ◽  
Author(s):  
Kazuaki Nagasaka ◽  
Naofumi Otsuru ◽  
Rui Sato ◽  
Hiraku Watanabe ◽  
Noriko Sakurai ◽  
...  
Keyword(s):  
Psychometric Properties ◽  
Morphometric Study ◽  
Healthy Individuals

scholarly journals Sex differences in regional gray matter in healthy individuals aged 44–48 years: A voxel-based morphometric study

NeuroImage ◽  
2007 ◽  
Vol 36 (3) ◽  
pp. 691-699 ◽  
Author(s):  
Xiaohua Chen ◽  
Perminder S. Sachdev ◽  
Wei Wen ◽  
Kaarin J. Anstey
Keyword(s):  
Sex Differences ◽  
Gray Matter ◽  
Morphometric Study ◽  
Healthy Individuals

scholarly journals Multiple sclerosis patients valuing their own health status: valuation and psychometric properties of the 15D

2016 ◽  
Vol 8 (3) ◽  
Author(s):  
Ioannis E. Dagklis ◽  
Vasilis H. Aletras ◽  
Efthymia Tsantaki ◽  
Anastasios Orologas ◽  
Dimitrios Niakas
Keyword(s):  
Multiple Sclerosis ◽  
Psychometric Properties ◽  
Cost Utility ◽  
Expanded Disability Status Scale ◽  
Healthy Individuals ◽  
Mental Functioning ◽  
Clinical Form ◽  
Ongoing Debate ◽  
Disability Status ◽  
Multiple Sclerosis Patients

An ongoing debate on decision and cost-utility analyses is whether to use preferences of general public or patients. The aim of this study was to replicate the valuation procedure of the multi-attribute utility generic measure, 15D, using a sample of multiple sclerosis (MS) patients and to assess its psychometric properties. Consecutive outpatient MS patients were recruited from two MS centers in Greece. The three-stage valuation procedure was applied and, with the use of elicited preference weights, an MS patients’ algorithm was developed. The original Finnish value set derived from healthy individuals was also used to calculate scores and a comparison between the two algorithms was made. A total of 64 MS patients were evaluated. The 15D scores obtained with the MS patients’ valuation algorithm were higher than the original one. The derived utilities differed significantly with respect to age, depressive symptoms, Expanded Disability Status Scale score and clinical form. MS patients indicated as most important domains mobility, mental functioning and vitality. Cronbach’s alpha was estimated 0.876 and correlations between relevant dimensions of the instruments were moderate to high. The 15D was generally feasible and reliable in patients with MS and the valuation system yielded acceptable psychometric properties.

scholarly journals Age and AgNor- A Morphometric study

2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Manpreet Kaur ◽  
Smita Naik ◽  
Sachin Jindal
Keyword(s):  
Epithelial Cells ◽  
Buccal Mucosa ◽  
Age Groups ◽  
Morphometric Study ◽  
Healthy Individuals ◽  
Oral Epithelial Cells ◽  
Glass Slides ◽  
Buccal Epithelial Cells ◽  
Oral Epithelial ◽  
Ribosome Biosynthesis

To investigate and correlate total AgNOR area/Total nucleus area (TAA/TNA ) values in buccal epithelial cells of healthy individuals in different age groups. Material and Methodology:- In present study 50 healthy individuals are included with age ranging 10 to 60 years. These are divided into 5 groups.Group1-10-20year, Group2-20- 30year, Group3-30-40year, Group4-40-50year, Group5-50-60year. Oral epithelial cells collected with the help of cyto brush from buccal mucosa. Smears were prepared on clean glass slides and fixed with 95% alcohol. Fixed slides Smears were stained with AgNOR stain. Results: Statistically significant correlations were found between mean TAA/TNA values and age p < 0.001 for linear and p < 0.0001 for polynominal regression, and between AgNOR number and age, p < 0.001 for linear. Conclusion: There is a significant correlation between age and AgNOR amount (ribosome biosynthesis rate) in buccal epithelial cells of healthy individuals. AgNORs in buccal epithelial cells may be used for detection of age.

scholarly journals Psychometric properties of knee proprioception tests targeting healthy individuals and those with anterior cruciate ligament injury managed with or without reconstruction: a systematic review protocol

BMJ Open ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. e027241
Author(s):  
Ashokan Arumugam ◽  
Andrew Strong ◽  
Eva Tengman ◽  
Ulrik Röijezon ◽  
Charlotte K Häger
Keyword(s):  
Systematic Review ◽  
Anterior Cruciate Ligament ◽  
Psychometric Properties ◽  
Cruciate Ligament ◽  
Acl Injury ◽  
Risk Of Bias ◽  
Cochrane Central Register ◽  
Healthy Individuals ◽  
Review Protocol ◽  
Anterior Cruciate

Introduction An anterior cruciate ligament (ACL) injury affects knee proprioception and sensorimotor control and might contribute to an increased risk of a second ACL injury and secondary knee osteoarthritis. Therefore, there is a growing need for valid, reliable and responsive knee proprioception tests. No previous study has comprehensively reviewed all the relevant psychometric properties (PMPs) of these tests together. The aim of this review protocol is to narrate the steps involved in synthesising the evidence for the PMPs of specific knee proprioception tests among individuals with an ACL injury and knee-healthy controls.Methods and analysisThe Preferred Reporting Items for Systematic reviews and Meta-Analyses will be followed to report the review. A combination of four conceptual groups of terms—(1) construct (knee proprioception), (2) target population (healthy individuals and those with an ACL injury managed conservatively or with a surgical reconstruction), (3) measurement instrument (specific knee proprioception tests) and (4) PMPs (reliability, validity and responsiveness)—will be used for electronic databases search. PubMed, AMED, CINAHL, SPORTDiscus, Web of Science, Scopus, the Cochrane Central Register of Controlled Trials and ProQuest will be searched from their inception to November 2018. Two reviewers will independently screen titles, abstracts and full text articles, extract data and perform risk of bias assessment using the updated COnsensus-based Standards for the selection of health Measurement INstruments risk of bias checklist for the eligible studies. A narrative synthesis of the findings and a meta-analysis will be attempted as appropriate. Each PMP of knee proprioception tests will be classified as ‘sufficient’, ‘indeterminate’ or ‘insufficient’. The overall level of evidence will be ascertained using an established set of criteria.Ethics and disseminationEthical approval or patient consent is not required for a systematic review. The review findings will be submitted as a series of manuscripts for peer-review and publication in scientific journals.PROSPERO registration numberCRD42018108014.

scholarly journals Self-rated impulsivity in healthy individuals, substance use disorder and ADHD: psychometric properties of the Swedish Barratt impulsiveness scale

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Lotfi Khemiri ◽  
Christoffer Brynte ◽  
Maija Konstenius ◽  
Joar Guterstam ◽  
Ingvar Rosendahl ◽  
...  
Keyword(s):  
Substance Use ◽  
Psychometric Properties ◽  
Attention Deficit ◽  
Factor Model ◽  
Reliability And Validity ◽  
Psychometric Evaluation ◽  
Model Fit ◽  
Healthy Individuals ◽  
Swedish Version ◽  
Barratt Impulsiveness Scale

Abstract Background Impulsivity is associated with several psychiatric disorders, including substance use disorders (SUD) and attention deficit hyperactivity disorder (ADHD). A widely used questionnaire to assess impulsivity is the Barratt Impulsiveness Scale (BIS), and the aim of the current study was to evaluate the psychometric properties of the Swedish version of the BIS (swe-BIS). Methods The original BIS was translated to Swedish and back-translated by an authorized translator. The swe-BIS was administered to healthy controls (n = 113), patients with alcohol use disorder (n = 97), amphetamine use disorder (n = 37) and attention deficit hyperactive disorder (ADHD; n = 26). A subset of subjects (n = 62) completed the swe-BIS twice within 1 week. Psychometric evaluation of the swe-BIS included assessment of different indices of reliability (internal consistency, test-retest and agreement) and validity (response processess, divergent and convergent). Confirmatory factor analyses (CFA) were performed to assess several indices of model fit in five different models based on previously suggested subscales. Results Cronbach’s alpha for all swe-BIS items in the full sample was 0.89, ranging from 0.78–0.87 within the different subgroups. The Pearson test-retest correlation for total score was 0.78 (p < 0.001), with greater test-retest correlations within compared to across different subscales. The Bland-Altman plot indicated high level of agreement between test and retest. The healthy individuals had lower swe-BIS score compared to the patients (t(267.3) = − 8.6; p < 0.001), and the swe-BIS total score was also significantly different between each of the four participant groups (p < 0.01 for all group comparisons). Furthermore, swe-BIS had greater correlations with impulsivity related scales compared to non-impulsivity related scales. The CFA analyses indicated that while no suggested model showed an optimal fit, the best model fit indices was found for the 3-factor model. Conclusions The swe-BIS was found to have good to excellent psychometric properties with respect to the assessed indices of reliability and validity, supporting use of the scale in clinical research in both healthy individuals and patients with SUD and ADHD.

Morphological and elemental analysis of isolated incubated frog retina-choroid

1984 ◽  
Vol 42 ◽  
pp. 298-299
Author(s):  
B. J. Panessa-Warren ◽  
J. B. Warren ◽  
H. W. Kraner
Keyword(s):  
Elemental Analysis ◽  
Pigment Epithelium ◽  
Human Retina ◽  
Healthy Individuals ◽  
Anterior Portion ◽  
Pathological Conditions ◽  
Frog Retina ◽  
Isolated Retina ◽  
Vertebrate Eye ◽  
Retina Pigment Epithelium

Our previous studies have demonstrated that abnormally high amounts of calcium (Ca) and zinc (Zn) can be accumulated in human retina-choroid under pathological conditions and that barium (Ba), which was not detected in the eyes of healthy individuals, is deposited in the retina pigment epithelium (RPE), and to a lesser extent in the sensory retina and iris. In an attempt to understand how these cations can be accumulated in the vertebrate eye, a morphological and microanalytical study of the uptake and loss of specific cations (K, Ca,Ba,Zn) was undertaken with incubated Rana catesbiana isolated retina and RPE preparations. Large frogs (650-800 gms) were dark adapted, guillotined and their eyes enucleated in deep ruby light. The eyes were hemisected behind the ora serrata and the anterior portion of the eye removed. The eyecup was bisected along the plane of the optic disc and the two segments of retina peeled away from the RPE and incubated.

Clausal Density Between Ages 4 and 9 Years for the Edmonton Narrative Norms Instrument: Reference Data and Psychometric Properties

2020 ◽  
pp. 1-15
Author(s):  
Ling-Yu Guo ◽  
Phyllis Schneider ◽  
William Harrison
Keyword(s):  
Diagnostic Accuracy ◽  
Psychometric Properties ◽  
Language Impairment ◽  
Reference Data ◽  
Reliability And Validity ◽  
Correlation Coefficients ◽  
Criterion Validity ◽  
Likelihood Ratios ◽  
Generation Task ◽  
Sensitivity Specificity

Purpose This study provided reference data and examined psychometric properties for clausal density (CD; i.e., number of clauses per utterance) in children between ages 4 and 9 years from the database of the Edmonton Narrative Norms Instrument (ENNI). Method Participants in the ENNI database included 300 children with typical language (TL) and 77 children with language impairment (LI) between the ages of 4;0 (years;months) and 9;11. Narrative samples were collected using a story generation task, in which children were asked to tell stories based on six picture sequences. CD was computed from the narrative samples. The split-half reliability, concurrent criterion validity, and diagnostic accuracy were evaluated for CD by age. Results CD scores increased significantly between ages 4 and 9 years in children with TL and those with LI. Children with TL produced higher CD scores than those with LI at each age level. In addition, the correlation coefficients for the split-half reliability and concurrent criterion validity of CD scores were all significant at each age level, with the magnitude ranging from small to large. The diagnostic accuracy of CD scores, as revealed by sensitivity, specificity, and likelihood ratios, was poor. Conclusions The finding on diagnostic accuracy did not support the use of CD for identifying children with LI between ages 4 and 9 years. However, given the attested reliability and validity for CD, reference data of CD from the ENNI database can be used for evaluating children's difficulties with complex syntax and monitoring their change over time. Supplemental Material https://doi.org/10.23641/asha.13172129

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