scholarly journals Validation of plasma free haemoglobin analysis using H index on Roche Cobas C 701/702

Pathology ◽  
2020 ◽  
Vol 52 ◽  
pp. S59
Author(s):  
R. Campbell Heron ◽  
Leah Ha
Keyword(s):  
H Index ◽  
2018 ◽  
Vol 56 (5) ◽  
pp. 776-788 ◽  
Author(s):  
Nora Nikolac Gabaj ◽  
Marijana Miler ◽  
Alen Vrtarić ◽  
Marina Hemar ◽  
Petra Filipi ◽  
...  

AbstractBackground:The aim of our study was to perform verification of serum indices on three clinical chemistry platforms.Methods:This study was done on three analyzers: Abbott Architect c8000, Beckman Coulter AU5800 (BC) and Roche Cobas 6000 c501. The following analytical specifications were verified: precision (two patient samples), accuracy (sample with the highest concentration of interferent was serially diluted and measured values compared to theoretical values), comparability (120 patients samples) and cross reactivity (samples with increasing concentrations of interferent were divided in two aliquots and remaining interferents were added in each aliquot. Measurements were done before and after adding interferents).Results:Best results for precision were obtained for the H index (0.72%–2.08%). Accuracy for the H index was acceptable for Cobas and BC, while on Architect, deviations in the high concentration range were observed (y=0.02 [0.01–0.07]+1.07 [1.06–1.08]x). All three analyzers showed acceptable results in evaluating accuracy of L index and unacceptable results for I index. The H index was comparable between BC and both, Architect (Cohen’s κ [95% CI]=0.795 [0.692–0.898]) and Roche (Cohen’s κ [95% CI]=0.825 [0.729–0.922]), while Roche and Architect were not comparable. The I index was not comparable between all analyzer combinations, while the L index was only comparable between Abbott and BC. Cross reactivity analysis mostly showed that serum indices measurement is affected when a combination of interferences is present.Conclusions:There is heterogeneity between analyzers in the hemolysis, icteria, lipemia (HIL) quality performance. Verification of serum indices in routine work is necessary to establish analytical specifications.


2007 ◽  
Vol 148 (4) ◽  
pp. 165-171
Author(s):  
Anna Berhidi ◽  
Edit Csajbók ◽  
Lívia Vasas

Nobody doubts the importance of the scientific performance’s evaluation. At the same time its way divides the group of experts. The present study mostly deals with the models of citation-analysis based evaluation. The aim of the authors is to present the background of the best known tool – Impact factor – since, according to the authors’ experience, to the many people use without knowing it well. In addition to the „nonofficial impact factor” and Euro-factor, the most promising index-number, h-index is presented. Finally new initiation – Index Copernicus Master List – is delineated, which is suitable to rank journals. Studying different indexes the authors make a proposal and complete the method of long standing for the evaluation of scientific performance.


2019 ◽  
Vol 3 ◽  
pp. 13 ◽  
Author(s):  
Vishnu Chandra ◽  
Neil Jain ◽  
Pratik Shukla ◽  
Ethan Wajswol ◽  
Sohail Contractor ◽  
...  

Objectives: The integrated interventional radiology (IR) residency has only been established relatively recently as compared to other specialties. Although some preliminary information is available based on survey data five, no comprehensive bibliometric analysis documenting the importance of the quantity and quality of research in applying to an integrated-IR program currently exists. As the first bibliometric analysis of matched IR residents, the data obtained from this study fills a gap in the literature. Materials and Methods: A list of matched residents from the 2018 integrated-IR match were identified by contacting program directors. The Scopus database was used to search for resident research information, including total publications, first-author publications, radiology-related publications, and h-indices. Each matriculating program was categorized into one of five tiers based on the average faculty Hirsch index (h-index). Results: Sixty-three programs and 117 matched residents were identified and reviewed on the Scopus database. For the 2018 cycle, 274 total publications were produced by matched applicants, with a mean of 2.34 ± 0.41 publication per matched applicant. The average h-index for matched applicants was 0.96 ± 0.13. On univariate analysis, the number of radiology-related publications, highest journal impact factor, and h-index were all associated with an increased likelihood of matching into a higher tier program (P < 0.05). Other research variables displayed no statistical significance. All applicants with PhDs matched into tier one programs. Conclusions: Research serves as an important element in successfully matching into an integrated-IR residency. h-index, number of radiology-related manuscripts, and highest journal impact factors are all positively associated with matching into a higher tier program.


2020 ◽  
Vol 21 (9) ◽  
pp. 685-703
Author(s):  
Waseem Hassan ◽  
Jean Paul Kamdem ◽  
Mohammad Amjad Kamal ◽  
Joao Batista Teixeira da Rocha

Background: Scopus is regularly covering Current Drug Metabolism from 2000 onwards. Objective: The major objective is to perform the 1st bibliometric analysis of Current Drug Metabolism (CDM). Methods: The data was retrieved from Scopus in April-May 2020 for detail analysis. Results: The total number of publications was found to be 1551, with 955 reviews (61.57%) and 466 articles (30.05%). From 2000 onwards, we calculated the relative growth rate and doubling time. Based on the number of publications, total 4418 authors, 3235 institutions and 83 countries were directly involved in all publications. M.A. Kamal is the highly productive scientist with fifty-three (53 or 3.73%) publications, King Abdulaziz University is the top university with the highest number of publications (58 or 4.13%) and the USA is the top-ranked country with 365 publications (25.96%). We also provided the h-index, total citations (TC), h-index without self-citations (WSC) and total WSC of the top ten authors, universities and countries. In citations analysis, Prof. Zhou S.F. was the top scientist with the highest (1594) number of citations. In institutional category Department of Drug Metabolism, Merck Research Laboratories, Rahway, United States, is the top ranked institutes with 654 total citations. While, United States is the top-ranked country with 18409 total citations. In co-words analysis, 3387, 30564 and 17333 terms in titles of the manuscripts, abstracts and keywords were recorded, respectively. This indicated that CDM principally focused on understanding drug development ranging from its efficacy to delivery, metabolism, distribution, safety and mechanism of actions. Similarly, various specific drugs were thoroughly discussed in publications. Various enzymatic, genetics, proteins and cancer-related aspects were also described. For data presentations, we used VOSviewer graphical maps. Conclusion: The data confirm that CDM showed continuous growth in the number of publications and citations. However significant measures are needed to make overall progress and improve the rankings in relevant categories.


Author(s):  
Asifa Jan ◽  
Suhail Ahmed ◽  
Nahida Tun Nisa ◽  
Asiya Ahmed

The study maps the research output from University of Kashmir, one of the premier higher education institutes of Jammu&Kashmir state, India. Elseviers SciVerse Scopus one of the leading indexing abstracting services was queried for a period of 1963- February 2015 using the affiliation search feature for University of Kashmir. The works of the authors affiliated with University of Kashmir have been analyzed. Statistical analysis of the retrieved data was performed. The publication output from University of Kashmir has shown a promising growth expect for some years in 1990s which can be attributed to the political instability in the state. The highest contributing authors are from Science disciplines with authors from Chemistry, Botany, Electronics, Biochemistry, and Centre of Research for Development departments having a higher rate of h-Index. Majority of papers are published in Indian sources followed by the sources from US, Germany and China. Majority of the authors are affiliated with University of Kashmir followed by Indian Institute of Integrative Medicine (Earlier Regional Research Laboratory, Sanat Nagar), Sher-i-Kashmir Institute of Medical Sciences (SKIMS) and Aligarh Muslim University. Articles have remained a prime document type for publishing by the authors from University of Kashmir followed by conference proceedings and review articles. Agricultural and Biological Sciences outscore other disciplines followed by Biochemistry, Genetics & Molecular Biology and Medicine. Future emphasis on joint research, international collaboration, and publishing in indexed journals is needed.


2020 ◽  
Author(s):  
Takumi Kawashita ◽  
Sara Shu ◽  
Teevit Dunnsiri ◽  
Andrew Fung ◽  
Brian Bui ◽  
...  

BACKGROUND YouTube is a popular American video-sharing platform that has been accessible to the public since 2005. Previous studies have shown that YouTube is potentially beneficial to medical education, but the quality of videos still need to be determined. OBJECTIVE The goal of this study is to understand the quality of the YouTube videos by evaluating the characteristics of physicians and the total number of views on videos regarding fibromyalgia. METHODS The term “fibromyalgia” was searched on the YouTube search engine by relevance, the default setting. Information from the first 100 videos were analyzed. A search was performed on Scopus to determine the h-index and fibromyalgia-related publication for any physician who was featured in the videos. RESULTS Of the top 100 videos, there were 64 academic videos, 18 vlogs, 5 interview videos, and 13 miscellaneous videos. Out of the 64 academic videos, 30 physicians, 7 Doctors of Philosophy (Ph.D.), 5 physical therapists, and 5 chiropractors were identified. The majority physicians have an adequate academic affiliation such as h-index and academic publications. CONCLUSIONS Residents and medical students will encounter a large number of academic videos on fibromyalgia on YouTube. This study suggests that many videos were posted for academic purposes and that the quality of the videos can be ensured to some degree. However, developing a better systemic evaluation of the quality of YouTube content is still necessary.


Author(s):  
Gianfranco Pacchioni

This chapter discusses how performance is measured in science, such as through the role of citation metrics. Next, the chapter discusses the pros and cons of bibliometric indexes, and of ‘impact factor’, which was introduced by Eugene Garfield in 1955 but not widely used until twenty years later. The various ways that journals attempt to improve their impact factors, and how this will affect science, are also examined. Besides impact factor, the role played by indicators in evaluating scientists, such as the recently introduced h-index, is explored. Finally, fashions and trends in science are touched upon, illustrated with personal anecdotes from the author.


2020 ◽  
Vol 237 (11) ◽  
pp. 3295-3302
Author(s):  
Hannelore Findeis ◽  
Cathrin Sauer ◽  
Anthony Cleare ◽  
Michael Bauer ◽  
Philipp Ritter

Abstract Rationale Ketamine is the first widely used substance with rapid-onset antidepressant action. However, there are uncertainties regarding its potential urothelial toxicity, particularly after repeated application. In the context of rising recreational ketamine use, severe side effects affecting the human urinary tract have been reported. It is assumed that ketamine interacts with bladder urothelial cells and induces apoptosis. Objectives This study aimed to assess whether single or repeated doses of esketamine used in an antidepressant indication are associated with urinary toxicity. Methods We included male and female inpatients with a current episode of depression and a diagnosis of recurrent depressive disorder, bipolar disorder or schizoaffective disorder according to ICD-10 criteria (n = 25). The esketamine treatment schedule involved a maximum of 3× weekly dosing at 0.25–0.5 mg/kg i.v. or s.c. The primary outcome was the change in urine toxicity markers (leukocytes, erythrocytes, protein and free haemoglobin). Description of demographic, clinical and laboratory data was conducted using means, standard deviations, frequencies and percentages. Changes in urinary toxicity markers over time were evaluated using linear mixed models with gender as a covariate. Results The participants received an average of 11.4 (SD 8) esketamine treatments, and an average number of 11.2 (SD 8) urine samples were analysed over the course of treatment. Neither urinary leukocyte concentration (F(20; 3.0) = 3.1; p = 0.2) nor erythrocyte concentration (F(20;2.2) = 4.1; p = 0.2) showed a significant trend towards increase during the course of esketamine treatment. Similarly, free haemoglobin and protein concentrations, which were analysed descriptively, did not display a rise during treatment. There was a significant improvement in depression ratings after esketamine treatment (p < 0.001). Conclusions This study is, to the best of our knowledge, the first to focus on urothelial toxicity of esketamine used in antidepressant indication and dose. The results indicate that the use of single or repeated doses of esketamine is unlikely to cause urothelial toxicity. The results are in need of confirmation as sample size was small.


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