scholarly journals Organic-inorganic hybrid coatings containing phosphorus precursors prepared by sol–gel on Ti6Al4V alloy: Electrochemical and in-vitro biocompatibility evaluation

2020 ◽  
Vol 148 ◽  
pp. 105834 ◽  
Author(s):  
A.A. El hadad ◽  
F.R. García-Galván ◽  
M.A. Mezour ◽  
G.J. Hickman ◽  
I.E. Soliman ◽  
...  
2014 ◽  
Vol 2 (24) ◽  
pp. 3886-3896 ◽  
Author(s):  
A. A. El hadad ◽  
V. Barranco ◽  
A. Jiménez-Morales ◽  
E. Peón ◽  
G. J. Hickman ◽  
...  

Application of novel organic–inorganic hybrid sol–gel coatings containing dispersed hydroxyapatite particles improved the biocompatibility and corrosion protection properties of the Ti6Al4V alloy used in medical implants.


2020 ◽  
Vol 33 ◽  
pp. 1781-1786 ◽  
Author(s):  
Maria P. Nikolova ◽  
Veselina Nikolova ◽  
Veronika L. Ivanova ◽  
Stefan Valkov ◽  
Peter Petrov ◽  
...  

2014 ◽  
Vol 2 (45) ◽  
pp. 7955-7963 ◽  
Author(s):  
A. A. El hadad ◽  
V. Barranco ◽  
A. Jiménez-Morales ◽  
G. J. Hickman ◽  
J. C. Galván ◽  
...  

Introduction of phosphorous into hybrid silica sol–gel coatings on Ti6Al4V gives materials demonstrating higher levels of intermolecular condensation and fibrinogen uptake as well as improved in vitro biocompatibility and corrosion protection.


2008 ◽  
Vol 47-50 ◽  
pp. 1319-1322
Author(s):  
Yang Zhao ◽  
Pei Yin ◽  
Zu Yong Wang ◽  
Lei Ren ◽  
Qi Qing Zhang

Novel hybrid biomaterial of gelatin-siloxane nanoparticles (GS NPs), with positive surface potential and lower cytotoxicity, was synthesized through a 2-step sol-gel process. The pDNA-GS NPs complex was formulated with high encapsulation efficiency, and exhibited and efficient transfection in vitro. We thus envision that the GS NPs material could serve as non-viral gene vectors for gene therapy.


2018 ◽  
Author(s):  
Flavia Bollino ◽  
Elisabetta Tranquillo ◽  
Federico Barrino ◽  
Michelina Catauro

Author(s):  
Stefan Holberg

This chapter focuses on resins based on non-hydrolyzed, monomeric and polymeric alkoxysilanes. As alternative to classical sol-gel processing, the resins are applied to a surface without a preceding hydrolysis step. Only after application, hydrolysis and condensation of the alkoxysilyl groups occur by means of atmospheric moisture to result cross-linked organic-inorganic hybrid coatings. While the use of non-hydrolyzed silanes is well established, for example by applying polyethyl silicate as binder for zinc-rich anti-corrosive primers, this chapter describes the chemical structures of various novel organic-inorganic hybrid precursors that have significantly extended the area of application to adhesives and scratch-resistant, repellent, or anti-fouling coatings. At present, individual resins are produced and applied at industrial scale in the fields of protective coatings and automotive topcoats.


2018 ◽  
Vol 24 (8) ◽  
pp. 5901-5906
Author(s):  
U Anjaneyulu ◽  
B Priyadarshini ◽  
U Vijayalakshmi

Present paper deals with the development of hybrid nanocomposites which combination of Ag doped Hydroxyapatite (Ag:HAP)-Magnetite nanoparticles (Fe3O4NPs) and Chitosan. In this present investigation, we have employed sol–gel method to synthesize Ag:HAP using 5% of Ag concentrations. Furthermore, co-precipitation technique was employed to prepare Fe3O4 NPs and Ag doped HAP was mixed with it to develop hybrid composites. The planetary ball milling technique was used to incorporate the fabricated Ag:HAP-Fe3O4 composite material into the biopolymer chitosan at wt% of 50:25:25 respectively. In Vitro biocompatibility of Ag:HAP-Fe3O4 CS hybrid composites were evaluated by MTT assay using MG-63 cell lines for 24–48 h at 200–1000 μg/ml concentrations. Further, these hybrid composites were characterized by using ATR-FTIR, XRD and SEM techniques. The fabricated hybrid composite was found to be biologically compatible with MG-63 osteoblast cell lines to use in biomedical applications.


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