scholarly journals Dietary chitooligosaccharide supplementation alleviates intestinal barrier damage, and oxidative and immunological stress in lipopolysaccharide-challenged laying hens

2022 ◽  
pp. 101701
Author(s):  
Y.F. Gu ◽  
Y.P. Chen ◽  
R. Jin ◽  
C. Wang ◽  
C. Wen ◽  
...  
Keyword(s):  
Laying Hens ◽  
Intestinal Barrier ◽  
Immunological Stress

Alterations in cecal microbiota and intestinal barrier function of laying hens fed on fluoride supplemented diets

2020 ◽  
Vol 193 ◽  
pp. 110372 ◽  
Author(s):  
Liping Miao ◽  
Yujie Gong ◽  
Huaiyu Li ◽  
Chao Xie ◽  
Qianqian Xu ◽  
...  
Keyword(s):  
Barrier Function ◽  
Laying Hens ◽  
Intestinal Barrier ◽  
Intestinal Barrier Function ◽  
Cecal Microbiota

scholarly journals Probiotic mixture ameliorates heat stress of laying hens by enhancing intestinal barrier function and improving gut microbiota

2016 ◽  
Vol 16 (2) ◽  
pp. 292-300 ◽  
Author(s):  
Panwang Zhang ◽  
Tao Yan ◽  
Xiliang Wang ◽  
Shichang Kuang ◽  
Yuncai Xiao ◽  
...  
Keyword(s):  
Heat Stress ◽  
Gut Microbiota ◽  
Barrier Function ◽  
Laying Hens ◽  
Intestinal Barrier ◽  
Intestinal Barrier Function

scholarly journals Dietary Valine Ameliorated Gut Health and Accelerated the Development of Nonalcoholic Fatty Liver Disease of Laying Hens

2021 ◽  
Vol 2021 ◽  
pp. 1-37
Author(s):  
Huafeng Jian ◽  
Sasa Miao ◽  
Yating Liu ◽  
Xiaoming Wang ◽  
Qianqian Xu ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Liver Disease ◽  
Inflammatory Response ◽  
Fatty Liver Disease ◽  
Laying Hens ◽  
Intestinal Inflammation ◽  
Intestinal Barrier ◽  
Gut Health ◽  
Nonalcoholic Fatty Liver

Valine is an important essential amino acid of laying hens. Dietary supplemented with BCAAs ameliorated gut microbiota, whereas elevated blood levels of BCAAs are positively associated with obesity, insulin resistance, and diabetes in both humans and rodents. General controlled nonrepressed (GCN2) kinase plays a crucial role in regulating intestinal inflammation and hepatic fatty acid homeostasis during amino acids deficiency, while GCN2 deficient results in enhanced intestinal inflammation and developed hepatic steatosis. However, how long-term dietary valine impacts gut health and the development of nonalcoholic fatty liver disease (NAFLD) remains unknown. Hence, in the present study, we elucidated the effects of dietary valine on intestinal barrier function, microbial homeostasis, and the development of NAFLD. A total of 960 healthy 33-weeks-old laying hens were randomly divided into five experimental groups and fed with valine at the following different levels in a feeding trial that lasted 8 weeks: 0.59, 0.64, 0.69, 0.74, and 0.79%, respectively. After 8 weeks of treatment, related tissues and cecal contents were obtained for further analysis. The results showed that diet supplemented with valine ameliorated gut health by improving intestinal villus morphology, enhancing intestinal barrier, decreasing cecum pathogenic bacteria abundances such as Fusobacteriota and Deferribacterota, and inhibiting inflammatory response mediated by GCN2. However, long-term intake of high levels of dietary valine (0.74 and 0.79%) accelerated the development of NAFLD of laying hens by promoting lipogenesis and inhibiting fatty acid oxidation mediated by GCN2-eIF2α-ATF4. Furthermore, NAFLD induced by high levels of dietary valine (0.74 and 0.79%) resulted in strengthening oxidative stress, ER stress, and inflammatory response. Our results revealed that high levels of valine are a key regulator of gut health and the adverse metabolic response to NAFLD and suggested reducing dietary valine as a new approach to preventing NAFLD of laying hens.

Dietary Bacillus subtilis- based direct-fed microbials alleviate LPS-induced intestinal immunological stress and improve intestinal barrier gene expression in commercial broiler chickens

2017 ◽  
Vol 114 ◽  
pp. 236-243 ◽  
Author(s):  
Ujvala Deepthi Gadde ◽  
Sungtaek Oh ◽  
Youngsub Lee ◽  
Ellen Davis ◽  
Noah Zimmerman ◽  
...  
Keyword(s):  
Gene Expression ◽  
Bacillus Subtilis ◽  
Broiler Chickens ◽  
Intestinal Barrier ◽  
Immunological Stress ◽  
Commercial Broiler

scholarly journals Dietary vitamin D3 supplementation protects laying hens against lipopolysaccharide-induced immunological stress

2018 ◽  
Vol 15 (1) ◽  
Author(s):  
Yanqiang Geng ◽  
Qiugang Ma ◽  
Zhong Wang ◽  
Yuming Guo
Keyword(s):  
Vitamin D3 ◽  
Laying Hens ◽  
Dietary Vitamin ◽  
Immunological Stress ◽  
Vitamin D3 Supplementation

scholarly journals Effects of dietary threonine supplementation on intestinal barrier function and gut microbiota of laying hens

2017 ◽  
Vol 96 (10) ◽  
pp. 3654-3663 ◽  
Author(s):  
X.Y. Dong ◽  
M.M.M. Azzam ◽  
X.T. Zou
Keyword(s):  
Gut Microbiota ◽  
Barrier Function ◽  
Laying Hens ◽  
Intestinal Barrier ◽  
Intestinal Barrier Function

Protein kinase C (PKC)-β1 mediates EGF-induced protection of the microtubule (MT) cytoskeleton & intestinal barrier function (BF) against oxidant injury

2001 ◽  
Vol 120 (5) ◽  
pp. A701-A701
Author(s):  
A BANAN ◽  
J FIELDS ◽  
Y ZHANG ◽  
E MUTLU ◽  
A KESHAVARZIAN
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Barrier Function ◽  
Intestinal Barrier ◽  
Intestinal Barrier Function ◽  
Oxidant Injury ◽  
Kinase C

Effect of Vitamin D3 on Cadmium Retention by Laying Hens

2002 ◽  
Vol 52 (2) ◽  
pp. 81-84
Author(s):  
B. Koréneková ◽  
A. Jacková ◽  
J. Kottferová ◽  
P. Siklenka ◽  
M. Skalická ◽  
...  
Keyword(s):  
Vitamin D ◽  
Laying Hens
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