Relapse in involuntary substance treatment: a transversal study

In patients with obstructive sleep apnoea (OSA), a consequence of the intermittent hypoxia is nocturia. The frequency of nocturia related OSA is increased because many pathological pathways are present simultaneously. The aim was to assess the prevalence of nocturia among OSA patients and to identify the relationship with OSA and its comorbidities. A transversal study determining the prevalence of OSA�s comorbidities and nocturia related OSA and smoking was assessed, from 2011 to 2015, in 2 Romanian centres of Somnology, in Constanta county. All patients suspected of sleep breathing disorders were investigated by polygraphy and all patients diagnosed with OSA were recruited. Demographic and clinical characteristics were assessed, including the onset of nocturia. The comparison between groups with and without nocturia was performed using SPSS software, using Anova for numerical outcomes and c2 test for the categorical ones. Nocturia was highly prevalent (62.75 %) among 204 OSA patients, especially in elderly (p [ 0.00001). High blood pressure (hypertension), obstructive pulmonary disease (COPD), smoking exposure were more frequently reported in the OSA patients presenting nocturia (p[0.05). Type 2 diabetes and cardiac failure were also frequent, but did not reach a significant threshold of 95%. In conclusion, the nocturia is a frequent symptom and it is influenced by the OSA severity and comorbidities as hypertension and COPD. A further multidisciplinary approach in these patients is justified, especially in smokers.

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Patients with multiple sclerosis do not necessarily consume more alcohol or tobacco than the general population

Arquivos de Neuro-Psiquiatria ◽

10.1590/0004-282x20150117 ◽

2015 ◽

Vol 73 (10) ◽

pp. 828-833 ◽

Cited By ~ 3

Author(s):

Yara Dadalti Fragoso ◽

Sidney Gomes ◽

Marcus Vinicius M. Goncalves ◽

Suzana C. Nunes Machado ◽

Rogerio de Rizo Morales ◽

...

Keyword(s):

Multiple Sclerosis ◽

Alcohol Consumption ◽

General Population ◽

Alcohol Misuse ◽

Case Control ◽

Control Population ◽

Higher Alcohol ◽

Control Subjects ◽

Culturally Different ◽

Transversal Study

Purpose Recent papers suggest that patients with multiple sclerosis (MS) are prone to alcohol misuse. This may be due to the combination of a lifelong and disabling disease with a psychiatric profile typical of MS. The objective of the present study was to assess these findings in a culturally different population of patients with MS.Method The present case-control transversal study assessed 168 patients with MS and 168 control subjects from Brazil.Results There were no evidence that patients with MS drank more alcohol or, smoked more than did controls. In fact, control subjects had a significantly higher alcohol consumption. The only trait associated to higher alcohol consumption was anxiety, both for patients and controls.Conclusion Unlike previous reports in the literature, patients with MS in our study did not drink or smoked more than a control population.

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The Importance of Platelet Glycoside Residues in the Haemostasis of Patients with Immune Thrombocytopaenia

Journal of Clinical Medicine ◽

10.3390/jcm10081661 ◽

2021 ◽

Vol 10 (8) ◽

pp. 1661

Author(s):

Andrés Ramírez-López ◽

María Teresa Álvarez Román ◽

Elena Monzón Manzano ◽

Paula Acuña ◽

Elena G. Arias-Salgado ◽

...

Keyword(s):

Platelet Count ◽

Sialic Acid ◽

Healthy Controls ◽

Caspase Activity ◽

Antibody Dependent Cellular Cytotoxicity ◽

Activation Markers ◽

Platelet Surface ◽

Mannose Binding ◽

Transversal Study ◽

Binding Lectin

Loss of sialic acid from the carbohydrate side chains of platelet glycoproteins can affect platelet clearance, a proposed mechanism involved in the etiopathogenesis of immune thrombocytopaenia (ITP). We aimed to assess whether changes in platelet glycosylation in patients with ITP affected platelet counts, function, and apoptosis. This observational, prospective, and transversal study included 82 patients with chronic primary ITP and 115 healthy controls. We measured platelet activation markers and assayed platelet glycosylation and caspase activity, analysing samples using flow cytometry. Platelets from patients with ITP with a platelet count <30 × 103/µL presented less sialic acid. Levels of α1,6-fucose (a glycan residue that can directly regulate antibody-dependent cellular cytotoxicity) and α-mannose (which can be recognised by mannose-binding-lectin and activate the complement pathway) were increased in the platelets from these patients. Platelet surface exposure of other glycoside residues due to sialic acid loss inversely correlated with platelet count and the ability to be activated. Moreover, loss of sialic acid induced the ingestion of platelets by human hepatome HepG2 cells. Changes in glycoside composition of glycoproteins on the platelets’ surface impaired their functional capacity and increased their apoptosis. These changes in platelet glycoside residues appeared to be related to ITP severity.

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Adolescent Substance Treatment Engagement Questionnaire for Incarcerated Teens

Journal of Substance Abuse Treatment ◽

10.1016/j.jsat.2015.04.011 ◽

2015 ◽

Vol 57 ◽

pp. 49-56 ◽

Cited By ~ 2

Author(s):

Rosemarie A. Martin ◽

Lynda A.R. Stein ◽

Mary Clair ◽

Mary Kathryn Cancilliere ◽

Warren Hurlbut ◽

...

Keyword(s):

Treatment Engagement ◽

Adolescent Substance ◽

Substance Treatment

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Treating Smokers in Substance Treatment With Contingent Vouchers, Nicotine Replacement and Brief Advice Adapted for Sobriety Settings

Journal of Substance Abuse Treatment ◽

10.1016/j.jsat.2016.08.012 ◽

2017 ◽

Vol 72 ◽

pp. 72-79 ◽

Cited By ~ 12

Author(s):

Damaris J. Rohsenow ◽

Rosemarie A. Martin ◽

Jennifer W. Tidey ◽

Suzanne M. Colby ◽

Peter M. Monti

Keyword(s):

Nicotine Replacement ◽

Substance Treatment ◽

Brief Advice

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Relationship between obstructive sleep apnea syndrome and functional capacity in patients with diabetes mellitus type 2: an observational transversal study

Revista da Associação Médica Brasileira ◽

10.1590/1806-9282.20210232 ◽

2021 ◽

Vol 67 (6) ◽

pp. 878-881

Author(s):

Moyrane Abreu da Fonseca ◽

Alana Karina Silva Moreira ◽

Railsa Bertilla dos Santos Lima ◽

Marcela de Araújo Oliveira ◽

Aldair Darlan Santos-de-Araújo ◽

...

Keyword(s):

Diabetes Mellitus ◽

Obstructive Sleep Apnea ◽

Sleep Apnea ◽

Diabetes Mellitus Type 2 ◽

Sleep Apnea Syndrome ◽

Obstructive Sleep ◽

Patients With Diabetes ◽

Apnea Syndrome ◽

Transversal Study

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Quality of Primary Health Care in Brazil: patients'view

Revista Brasileira de Enfermagem ◽

10.1590/0034-7167-2017-0656 ◽

2018 ◽

Vol 71 (suppl 6) ◽

pp. 2713-2719

Author(s):

Daniela Cristina Moreira Marculino de Figueiredo ◽

Helena Eri Shimizu ◽

Walter Massa Ramalho ◽

Alexandre Medeiros de Figueiredo ◽

Kerle Dayana Tavares de Lucena

Keyword(s):

Health Care ◽

Primary Health Care ◽

Health Services ◽

Clinical History ◽

Coordination Of Care ◽

Primary Health ◽

Comprehensive Health ◽

Access And Quality ◽

Transversal Study

ABSTRACT Objective: To describe the evaluation of patients that participated in the National Program for Improving the Access and Quality in Primary Health Care (Programa Nacional de Melhoria do Acesso e da Qualidade na Atenção Básica) for the comprehensive healthcare, the bond and the coordination of care in the country's macro-regions. Method: A descriptive, transversal study, from interviews with 65,391 patients of Primary Health Care, in 3,944 municipalities regarding the use of health services. Results: The professionals seek to solve the patients' problems in their unit (73.1%) but focused mainly on the scope of the appointment (65.6%) and offering care away from the population's reality (69.4%). Difficulties in the rescue of clinical history were referred (50.3%) and in the care performed in other health services (29.2%). Conclusion: The comprehensive health care, the bond and the coordination of care remain challenges to the Primary Health Care in the country, requiring reflections on the implementation of national policies, especially considering the regional diversities in Brazil.

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Sociodemographic, lifestyle and therapeutic predictors of 2-year survival in HIV-infected persons receiving antiretroviral therapy in Benin

Journal of Public Health in Africa ◽

10.4081/jphia.2017.651 ◽

2017 ◽

Vol 8 (1) ◽

Author(s):

Charles Sossa Jerome ◽

Maurice Agonnoudé ◽

Ghislain Emmanuel Sopoh ◽

Ali Imorou Bah-Chabi ◽

Amédée De Souza ◽

...

Keyword(s):

Antiretroviral Therapy ◽

Proportional Hazards ◽

Cox Proportional Hazards ◽

Proportional Hazards Regression ◽

Persons Living With Hiv ◽

Immunodeficiency Virus ◽

Living With Hiv ◽

Transversal Study ◽

Death Data ◽

Hiv Aids

The benefits of antiretroviral therapy (ART) for treating human immunodeficiency virus (HIV) infection have been well described. The objective of this study was to identify the predictors of two-year survival in persons living with HIV/AIDS (PLWHA) in Benin. This retrospective transversal study included all patients from 46 HIV/AIDS therapy sites across Benin who started ART between July 1st, 2011 and June 30th, 2012. The independent variables were patients’ sociodemographic, clinical, biological and therapeutic characteristics and their ART regimen. The main dependent variable was the time of death. Data were collected from medical records, using documentary review. Cox proportional hazards regression models were used to investigate factors associated with survival. Among the 771 PLWHA participants of the study, 18 (2.3%) died within the two-year period. The estimated mortality of the 771 PLWHA was 3% at 24 months. Among the sociodemographic, lifestyle and therapeutic characteristics studied, the main predictor of two-year mortality was poor adherence [odds ratio = 4.15, 95% confidence interval (1.55- 11.28)]. This study confirms that improving the survival of PLWHA receiving ART requires enhanced adherence.

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