Epithelioid Sarcoma of the Right Ilium Mimicking Sacroiliitis

2013 ◽  
Vol 9 (2) ◽  
pp. 120-122 ◽  
Author(s):  
Norberto Gómez Rodríguez ◽  
Ángeles Peteiro Cancelo ◽  
Jesús Ibáñez Ruán ◽  
Marisol González Pérez
Keyword(s):  
Epithelioid Sarcoma ◽  
The Right

scholarly journals Primary pulmonary epithelioid sarcoma: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Eiki Mizutani ◽  
Riichiro Morita ◽  
Keiko Abe ◽  
Makoto Kodama ◽  
Shogo Kasai ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Lung Tumor ◽  
Smooth Muscle Actin ◽  
Asbestos Exposure ◽  
Epithelioid Sarcoma ◽  
Whole Body ◽  
Health Examination ◽  
Positron Emission ◽  
Primary Lung Tumor ◽  
The Right

Abstract Background Epithelioid sarcoma most frequently occurs in the dermal or subcutaneous area of the distal extremities. To date, there have been three cases of primary pulmonary epithelioid sarcoma reported. We report a case of epithelioid sarcoma that is considered a primary lung tumor. Case presentation A 65-year-old asymptomatic Asian male patient underwent chest radiography during a routine health examination, and an abnormal mass was detected. His past medical history was unremarkable. He smoked 40 cigarettes every day and had slightly obstructive impairment on spirometry. He worked as an employee of a company and had no history of asbestos exposure. He underwent partial resection of the right lung by thoracoscopy. A histological examination of the tumor revealed a cellular nodule of epithelioid and spindle-shaped cells. Some of the tumor cells displayed rhabdoid features and reticular arrangement in a myxomatous stroma. Immunohistochemically, the tumor cells were positive for vimentin, smooth muscle actin (SMA), CD34, and epithelial membrane antigen (EMA); loss of the BAF47/INI1 protein in the tumor cells was also confirmed. A diagnosis of epithelioid sarcoma was established. Careful screening by whole-body positron emission tomography for another primary lesion after surgery did not detect any possible lesion. He had no cutaneous disease. Conclusion To our knowledge, this is the fourth case of a proximal-type epithelioid sarcoma considered as a primary lung tumor.

Primary Epithelioid Sarcoma of the Zygomatic Bone

2019 ◽  
Vol 22 (3) ◽  
pp. 252-257 ◽  
Author(s):  
Henry Tran ◽  
Nick Shillingford ◽  
Stefanie Thomas ◽  
Jeffrey Hammoudeh ◽  
Shengmei Zhou
Keyword(s):  
Tumor Cells ◽  
English Literature ◽  
Epithelioid Sarcoma ◽  
Chromosomal Microarray ◽  
Chromosomal Microarray Analysis ◽  
Zygomatic Bone ◽  
Facial Numbness ◽  
Resection Specimen ◽  
Weak Expression ◽  
The Right

Primary epithelioid sarcoma (ES) of bone is extremely rare with only 2 reported cases in the English literature. A previously healthy 18-year-old man presented with a 6-month history of right facial numbness and tingling and right eye diplopia. A computerized tomography scan revealed an ill-defined mass with dense osseous matrix centered in the right zygomatic bone. An outside biopsy was read as osteosarcoma. The resection specimen revealed large epithelioid and spindle cells embedded in a prominent hyalinized matrix with focal metaplastic bone formation. The tumor cells were strongly and diffusely positive for AE1/AE3 and epithelial membrane antigen, but a definitive diagnosis of ES was not immediately reached due to the presence of dense hyalinized matrix and weak expression of SAT2B by tumor cells. Deficient INI1 protein expression by immunohistochemistry and homozygous loss of the SMARCB1 gene by chromosomal microarray analysis ultimately justified this tumor’s designation as ES.

Epithelioid Sarcoma-like Hemangioendothelioma a Case Report

2005 ◽  
Vol 91 (5) ◽  
pp. 436-439 ◽  
Author(s):  
Cigdem Tokyol ◽  
Nüket Uzüm ◽  
Ilhami Kuru ◽  
Omer Uluoglu
Keyword(s):  
Case Report ◽  
Relevant Literature ◽  
Epithelioid Sarcoma ◽  
Vascular Tumor ◽  
Low Grade ◽  
Rare Entity ◽  
Anterior Aspect ◽  
Cubital Fossa ◽  
Painful Mass ◽  
The Right

Seven cases of an unusual low-grade vascular tumor were reported in a recent study. Despite its similarity to epithelioid sarcoma, this tumor was termed epithelioid sarcoma-like hemangioendothelioma because of the subtle histopathological and immunohistochemical differences. Another case of this rare entity in a 70-year-old woman who suffered from a painful mass on the anterior aspect of the right cubital fossa is presented here, together with a review of the relevant literature.

“Proximal-type” and Classic Epithelioid Sarcomas Represent a Clinicopathologic Continuum: Case Report

2005 ◽  
Vol 8 (1) ◽  
pp. 105-114 ◽  
Author(s):  
Dinesh Rakheja ◽  
Kathleen S. Wilson ◽  
John Meehan ◽  
Roger A. Schultz ◽  
Ana M. Gomez
Keyword(s):  
Case Report ◽  
Epithelioid Sarcoma ◽  
Right Hand ◽  
The Right

We report a case of an epithelioid sarcoma that occurred in the right hand of a 14-year-old boy and had the “proximal-type” morphology and a complex, near-tetraploid karyotype. The tumor metastasized to the lungs, where the morphology was typical for the classic epithelioid sarcoma. Based on the morphologic and cytogenetic findings in this case, we suggest that the proximal-type and the classic epithelioid sarcomas are not distinct entities but represent a continuum.

scholarly journals Ipsilateral breast metastasis after axillary dissection caused by epithelioid sarcoma: a case report and pathological investigation

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Luyan Chen ◽  
Li Wang ◽  
Xiaochen Zhang ◽  
Minya Yao ◽  
Peifen Fu
Keyword(s):  
Lymph Nodes ◽  
Epithelioid Sarcoma ◽  
Metastatic Breast ◽  
Axillary Lymph ◽  
Breast Metastasis ◽  
Ipsilateral Breast ◽  
Malignant Soft Tissue Tumor ◽  
Detailed Medical History ◽  
Axillary Mass ◽  
The Right

Abstract Background Epithelioid sarcoma (ES) is a rare malignant soft tissue tumor, commonly occurring in distal extremities, such as fingers, hands and wrists. For oncologists and surgeons, a female patient with enlarged axillary lymph node on one side only is easily diagnosed with an occult breast carcinoma rather than ES. Besides, whole breast metastasis of ES has not been reported yet. Case presentation A 47-year-old Chinese woman came to the outpatient clinic of First Affiliated Hospital of Zhejiang University (FAHZU) with a complaint of an asymptomatic right axillary mass for 3 months. Then she received surgical resection of the right axillary lymph nodes and right supraclavicular lymph nodes. According to the clinical tumor site and routine immunohistochemistry (IHC), suspicion of metastatic epithelial sarcoma and metastatic breast cancer could not be ruled out. Subsequently, with more detailed medical history review and physical examination, a mass on the right forearm was found, which was considered as the primary lesion. Further IHC and Molecular Genetics revealed that all the neoplastic cells exhibited loss of INI1 protein and were negative for ERG gene rearrangement yet positive for epithelial membrane antigen (EMA), cytokeratin (CK) 8, CK19, Vimentin, CD34. The final diagnosis was ES. She received postoperative chemotherapy, without radiotherapy. Unexpectedly, an ipsilateral breast metastasis was developed at ten months after surgery. Regrettably, there was no positive result of the metastatic breast sample, based on a genome sequencing by a 381-cancer-gene panel in a lab. Therefore, she went through another round of chemotherapy and took Apatinib for maintenance treatment. During the last follow-up (26 months after diagnosis), the disease was under control. Conclusion This rare but interesting case enables breast surgeons and pathologists to accumulate more experience of differential diagnosis of axillary mass for personalized treatment in clinical practice. Meanwhile, ipsilateral breast metastasis of ES we reported in the case urges that clinicians attach greater importance to the tumor metastasis mechanism.

scholarly journals Epithelioid sarcoma of the parapharyngeal space: A case report

Rare Tumors ◽  
2021 ◽  
Vol 13 ◽  
pp. 203636132110161
Author(s):  
Yun-Tian Li ◽  
Wen-Guang Luo ◽  
Hong-Yan Zhang
Keyword(s):  
Radiation Treatment ◽  
Parapharyngeal Space ◽  
Epithelioid Sarcoma ◽  
Excisional Biopsy ◽  
External Beam Radiation ◽  
Excision Biopsy ◽  
Beam Radiation ◽  
The Right ◽  
Radiological Studies

Epithelioid sarcoma (ES) was first described by Enzinger in 1970. It is a rare variant of soft tissue sarcoma with a 5-year overall survival (OS) rate of 50%. Here, we reported a case of epithelioid sarcoma in the parapharyngeal space of an adult, resulting in a favorable prognosis after chemotherapy and radiation therapy. A 34-year-old female who complained of pharynx pain and discomfort was suspected of having a tumor in the right parapharyngeal space by CT scan. Excision biopsy suggested epithelioid sarcoma. Clinical and radiological studies did not reveal tumor distant metastasis in the patient. After excisional biopsy, the patient underwent chemotherapy and external beam radiation treatment. She has remained alive for 2 years and 7 months without recurrence since her last treatment. In this paper, we also provide a detailed review of the role of radiotherapy in the treatment of epithelioid sarcoma in previously reported cases.

scholarly journals Proximal-type epithelioid sarcoma in pubic region expressing L-type amino acid transporter 1: A case report

2022 ◽  
Vol 10 ◽  
pp. 2050313X2110679
Author(s):  
Shunsuke Yahiro ◽  
Takuya Fujimoto ◽  
Ikuo Fujita ◽  
Toshihiro Takai ◽  
Toshiko Sakuma ◽  
...  
Keyword(s):  
Amino Acid ◽  
Malignant Tumors ◽  
Epithelioid Sarcoma ◽  
Essential Amino Acids ◽  
Amino Acid Transporter ◽  
Soft Tissue Neoplasm ◽  
Boron Neutron Capture ◽  
Acid Transporter ◽  
Early Tumor ◽  
The Right

Proximal-type epithelioid sarcoma is an aggressive malignant soft-tissue neoplasm, a “proximal” variant of epithelioid sarcoma, resistant to multimodal therapy and involved in early tumor-related death. Pertinent treatments are, therefore, continually being explored. A 24-year-old woman with nonmetastatic proximal-type epithelioid sarcoma, originating subcutaneously on the right side of the vulva, underwent surgical resection; the lesion recurred, however, leading to death 3 months after the second surgery. Here described is a case of proximal-type epithelioid sarcoma expressing L-type amino acid transporter 1 (LAT1) that transports essential amino acids and p-borono-L-phenylalanine (BPA)—the chemical compound used in boron neutron capture therapy (BNCT)—and is highly expressed in many malignant tumors. Recently, LAT1 has drawn attention, and relevant treatments have been studied—LAT1 inhibitor and BNCT. LAT1 expression in proximal-type epithelioid sarcoma may lead to cogent treatments for the disease.

Single-Staged Multilevel Spondylectomy for En Bloc Resection of an Epithelioid Sarcoma With Intradural Extension in the Cervical Spine: Technical Case Report

2015 ◽  
Vol 11 (4) ◽  
pp. E585-E593 ◽  
Author(s):  
Mohamad Bydon ◽  
Rafael De la Garza-Ramos ◽  
Ian Suk ◽  
Edward McCarthy ◽  
Yoshiya Yamada ◽  
...  
Keyword(s):  
Cervical Spine ◽  
Epithelioid Sarcoma ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
En Bloc ◽  
Recommended Treatment ◽  
Tumor Involvement ◽  
Long Term Prognosis ◽  
The Right

Abstract BACKGROUND AND IMPORTANCE Occurrence of spinal epithelioid sarcomas is rare, with few cases reported in the literature. Although wide local resection is the recommended treatment, this technique is challenging in the spine. CLINICAL PRESENTATION The case of a 17-year-old male with a recurrent epithelioid sarcoma with intradural extension in the cervical spine is presented. Because of nerve root involvement, the patient presented with right upper extremity weakness. The patient underwent a posterior C1-C4 spondylectomy to achieve an en bloc resection, followed by reconstruction from the occiput to T4. The right vertebral artery and C1-C4 nerve roots were sacrificed because of tumor involvement. After 3 years of follow-up the patient is disease-free but has persistent right deltoid weakness. CONCLUSION Cervical spondylectomy via a single-staged posterior approach is a challenging yet feasible procedure for the treatment of epithelioid sarcomas. To the best of the authors' knowledge, this is the first report of complete resection of an epithelioid sarcoma with intradural extension in the cervical spine. Although neurovascular structures may warrant sacrifice, this procedure may provide improved long-term prognosis.

Primary epithelioid sarcoma of the vulva

2001 ◽  
Vol 11 (4) ◽  
pp. 316-320 ◽  
Author(s):  
T. Kasamatsu ◽  
T. Hasegawa ◽  
H. Tsuda ◽  
S. Okada ◽  
M. Sawada ◽  
...  
Keyword(s):  
Lymph Node ◽  
Local Excision ◽  
Inguinal Lymph Node ◽  
Regional Lymph Node ◽  
Epithelioid Sarcoma ◽  
Pathology Report ◽  
Inguinal Lymphadenectomy ◽  
Lymph Node Swelling ◽  
Radical Vulvectomy ◽  
The Right

Abstract.Kasamatsu T, Hasegawa T, Tsuda H, Okada S, Sawada M, Yamada T, Tsunematsu R, Ohmi K, Mizuguchi K, Kawana T. Primary epithelioid sarcoma of the vulva.A case of a 31-year-old woman with epithelioid sarcoma of the vulva which metastasized to the regional lymph node 8 years after onset of the disease is reported here. The patient first noticed a painless subcutaneous mass of 5 mm in diameter in the right labium majus at age of 21. This was excised locally at age 23, but recurred 17 months later. Although local excision was again performed, the tumor recurred and continued to enlarge very slowly. At this stage, based on the pathology of both the initial and second tumors, the diagnosis was of a benign inflammatory process. However, local recurrence and inguinal lymph node swelling occurred at age 29, and biopsy was taken. The pathology report indicated benign granulomatous changes. The slides were reconsidered and re-interpreted as epithelioid sarcoma, whereupon radical vulvectomy was performed at age 31. Vulvar epithelioid sarcoma with inguinal lymph node metastasis was first diagnosed at that time. Epithelioid sarcoma of the vulva is an exceedingly rare tumor, and only 15 cases have been reported thus far in the literature. Early diagnosis and curative treatment of this tumor may be problematic for gynecologists because of its rarity and therefore little-known characteristic clinical behavior and histology. Radical vulvectomy or extensive local excision with inguinal lymphadenectomy at the time of diagnosis is recommended as the treatment of choice.

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