scholarly journals Gold nanoparticles as a drug delivery system for standard chemotherapeutics: A new lead for targeted pharmacological cancer treatments

2021 ◽  
Vol 11 ◽  
pp. e00685
Author(s):  
Mohamed Yafout ◽  
Amine Ousaid ◽  
Youssef Khayati ◽  
Ibrahim Sbai El Otmani
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Drug Delivery System ◽  
Delivery System ◽  
Cancer Treatments

scholarly journals AB023. Ultrastable gold nanoparticles as a drug delivery system for ocular therapy

2019 ◽  
Vol 4 ◽  
pp. AB023-AB023
Author(s):  
Florence Masse ◽  
Pascale Desjardins ◽  
Mathieu Ouellette ◽  
Camille Couture ◽  
Mahmoud Mohamed Omar ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Drug Delivery System ◽  
Delivery System ◽  
Ocular Therapy

Bovine serum albumin/gold nanoparticles as a drug delivery system for Curcumin: experimental and computational studies

2019 ◽  
Vol 38 (15) ◽  
pp. 4644-4654 ◽  
Author(s):  
Bahareh Khodashenas ◽  
Mehdi Ardjmand ◽  
Mazyar Sharifzadeh Baei ◽  
Ali Shokuhi Rad ◽  
Azim Akbarzadeh Khiyavi
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Drug Delivery System ◽  
Delivery System ◽  
Bovine Serum ◽  
Computational Studies

Thermo-responsive gold/poly(vinyl alcohol)-b-poly(N-vinylcaprolactam) core–corona nanoparticles as a drug delivery system

2014 ◽  
Vol 5 (18) ◽  
pp. 5289-5299 ◽  
Author(s):  
Ji Liu ◽  
Christophe Detrembleur ◽  
Marie Hurtgen ◽  
Antoine Debuigne ◽  
Marie-Claire De Pauw-Gillet ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Drug Delivery System ◽  
Delivery System ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
System P

Preparation of thermo-responsive poly(vinyl alcohol)-b-poly(N-vinylcaprolactam) copolymer-stabilized gold nanoparticles for drug delivery.

99mTc-citrate-gold nanoparticles as a tumor tracer: synthesis, characterization, radiolabeling and in-vivo studies

2020 ◽  
Vol 108 (10) ◽  
pp. 809-819 ◽  
Author(s):  
Basma M. Essa ◽  
Ahmed A. El-Mohty ◽  
Maher A. El-Hashash ◽  
Tamer M. Sakr
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Drug Delivery System ◽  
Delivery System ◽  
Solid Tumor ◽  
Tumor Imaging ◽  
In Vivo Studies ◽  
Post Injection ◽  
Tumor Bearing

AbstractTargeted drug delivery system can reduce the side effects of high drug concentration by improving drug pharmacokinetics at lower doses. Citrate-gold nanoparticles (AuNPs) as a drug delivery system were synthesized via green nanotechnology technique to be used as a new imaging platform for tumor targeting. Citrate-AuNPs were synthesized with core size of 10 nm. Citrate-AuNPs were labeled with technetium-99m (99mTc) with radiochemical yield of 95.20 ± 2.70% with good in-vitro stability in both saline and human serum and well in-vivo studied in both normal and solid tumor bearing mice. The in-vivo biodistribution study of [99mTc]Tc-citrate-AuNPs in solid tumor bearing mice (as preliminary study) showed a high accumulation in tumor site with tumor/muscle of 4.35 ± 0.22 after 30 min post injection. The direct intratumoral (I.T) injection of [99mTc]Tc-citrate-AuNPs showed that this complex was retained in the tumor up to 77.86 ± 1.90 % at 5 min and still around 50.00 ± 1.42 % after 30 min post injection (p.i.). The newly presented nano-platform could be presented as a new potential radiopharmaceutical tumor imaging probe.

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