scholarly journals Production of endo-β-mannanase, superoxide radicals, hydrogen peroxide, and peroxidase in the micropylar endosperm of pepper seed during germination is determined by the endosperm itself

2021 ◽  
pp. 110757
Author(s):  
Zhaowan Shi ◽  
Zhaoyang Li ◽  
Xueqin Yang ◽  
Yanyan He ◽  
Xiaofeng Wang
1982 ◽  
Vol 60 (11) ◽  
pp. 1330-1345 ◽  
Author(s):  
Ajit Singh

The spectrum of biological processes in which oxygen is used by living systems is quite large, and the products include some damaging species of activated oxygen, particularly the superoxide radical [Formula: see text] and hydrogen peroxide (H2O2). Superoxide radicals and hydrogen peroxide, in turn, can lead to the formation of other damaging species: hydroxyl radicals (∙OH) and singlet oxygen (1O2). Hydroxyl radicals react with organic compounds to give secondary free radicals that, in the presence of oxygen, yield peroxy radicals, peroxides, and hydroperoxides. Formation, interconversion, and reactivity of [Formula: see text] and related activated oxygen species, methods available for their detection, and the basis of their biological toxicity are briefly reviewed.


1997 ◽  
Vol 101 (30) ◽  
pp. 5822-5827 ◽  
Author(s):  
Yoshio Nosaka ◽  
Yoshifumi Yamashita ◽  
Hiroshi Fukuyama

1984 ◽  
Vol 224 (3) ◽  
pp. 697-701 ◽  
Author(s):  
J M C Gutteridge

The stimulatory effect of ferrous salts on the peroxidation of phospholipids can be enhanced by EDTA when the concentration of Fe2+ in the reaction is greater than that of EDTA. Hydroxyl-radical scavengers do not inhibit peroxidation until the concentrations of Fe2+ and EDTA in the reaction are equal. Lipid peroxidation is then substantially initiated by hydroxyl radicals derived from a Fenton-type reaction requiring hydrogen peroxide. Superoxide radicals appear to play some role in the formation of initiating species.


2013 ◽  
Vol 41 (02) ◽  
pp. 425-441 ◽  
Author(s):  
Tong Ho Kang ◽  
Bin Na Hong ◽  
Su-Young Jung ◽  
Jeong-Han Lee ◽  
Hong-Seob So ◽  
...  

Cisplatin is commonly used as a chemotherapeutic agent against many human cancers. However, it generates reactive oxygen species (ROS) and has serious dose-limiting side effects, including ototoxicity. The roots of Curculigo orchioides (C. orchioides) have been used to treat auditory diseases such as tinnitus and hearing loss in Chinese traditional medicine. In the present study, we investigated the protective effects of an ethanol extract obtained from C. orchioides rhizome (COR) on cisplatin-induced cell damage in auditory cells (HEI-OC1). COR (2.5–25 μg/ml) inhibited cisplatin-induced HEI-OC1 cell damage in a dose-dependent manner. To investigate the protective mechanism of COR on cisplatin cytotoxicity in HEI-OC1 cells, we measured the effects of COR on ROS generation and lipid peroxidation in cisplatin-treated cells as well as its scavenging activities against superoxide radicals, hydroxyl radicals, hydrogen peroxide, and DPPH radicals. COR (1–25 μg/ml) had scavenging activities against superoxide radicals, hydroxyl radicals, hydrogen peroxide, and DPPH radicals, as well as reduced lipid peroxidation. In in vivo experiments, COR was shown to reduce cochlear and peripheral auditory function impairments through cisplatin-induced auditory damage in mice. These results indicate that COR protects from cisplatin-induced auditory damage by inhibiting lipid peroxidation and scavenging activities against free radicals.


1993 ◽  
Vol 50 (8) ◽  
pp. 732-735
Author(s):  
V A Gusev ◽  
Danilovskaja YeV ◽  
Vatolkina OYe ◽  
O S Lomonosova ◽  
B T Velichkovsky

Sign in / Sign up

Export Citation Format

Share Document