Biochemical and molecular responses of maize (Zea mays L.) to 1,2-dibromo-4-(1,2 dibromoethyl) cyclohexane (TBECH) diastereomers: Oxidative stress, DNA damage, antioxidant enzyme gene expression and diversity of root exudates

2021 ◽  
Vol 753 ◽  
pp. 141872
Author(s):  
Honglin Huang ◽  
Lili Lv ◽  
Dan Wang ◽  
Bin Guo ◽  
Jitao Lv ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Gene Expression ◽  
Dna Damage ◽  
Zea Mays ◽  
Antioxidant Enzyme ◽  
Root Exudates ◽  
Zea Mays L ◽  
Molecular Responses ◽  
Enzyme Gene

scholarly journals Ascorbic acid coadministration with artesunate–amodiaquine, up-regulated antioxidant enzymes gene expression in bone marrow cells and elicited biochemical changes in Plasmodium berghei-infected mice

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Osamudiamen Ebohon ◽  
Francis Irabor ◽  
Ehimwenma Sheena Omoregie
Keyword(s):  
Oxidative Stress ◽  
Gene Expression ◽  
Bone Marrow ◽  
Antioxidant Enzymes ◽  
Antioxidant Enzyme ◽  
Plasmodium Berghei ◽  
Bone Marrow Cells ◽  
Enzyme Gene ◽  
Marrow Cells ◽  
Vit C

AbstractOne of the hallmarks of malaria infection is oxidative stress. This study was aimed at investigating the potential effects of coadministering a therapeutic dose of artesunate–amodiaquine (AS/AQ) with Vitamin C (Vit C) orally on some biochemical parameters and antioxidant enzymes gene expression in bone marrow cells of Plasmodium berghei-infected mice. Thirty male Swiss albino mice were divided into five groups of six mice each as follows: Basal control (not infected with P. berghei), Untreated (P. berghei-infected without treatment), Vit C, AS/AQ and AS/AQ + Vit C combination treated mice. Treatment was done twice daily for three consecutive days. Complete parasite clearance was observed on the second day of treatment in AS/AQ and AS/AQ + Vit C combination treated P. berghei-infected mice. Serum albumin and bilirubin levels were higher in the AS/AQ + Vit C combination treated P. berghei-infected mice compared with those treated with AS/AQ only. Artesunate–amodiaquine + Vit C combination increased superoxide dismutase activity and reduced hydrogen peroxide and malondialdehyde levels in P. berghei-infected mice when compared with the mice treated with only AS/AQ. Furthermore, AS/AQ + Vit C combination significantly up-regulated catalase and glutathione peroxidase-1 (GPx-1) mRNA expression compared with the mice treated with only AS/AQ. This is the first report linking AS/AQ to antioxidant enzyme gene expression in bone marrow cells. Our findings showed that AS/AQ and Vit C coadministration may be beneficial as it ameliorated oxidative stress and up-regulated antioxidant enzyme gene expression in P. berghei-infected mice.

Response of antioxidant defences to oxidative stress induced by prolonged exercise: antioxidant enzyme gene expression in lymphocytes

2006 ◽  
Vol 98 (3) ◽  
pp. 263-269 ◽  
Author(s):  
Nuria Cases ◽  
Antoni Sureda ◽  
Isabel Maestre ◽  
Pedro Tauler ◽  
Antoni Aguiló ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Gene Expression ◽  
Antioxidant Enzyme ◽  
Prolonged Exercise ◽  
Antioxidant Defences ◽  
Enzyme Gene

scholarly journals Silymarin-Enriched Biostimulant Foliar Application Minimizes the Toxicity of Cadmium in Maize by Suppressing Oxidative Stress and Elevating Antioxidant Gene Expression

Biomolecules ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 465
Author(s):  
Hesham F. Alharby ◽  
Hassan S. Al-Zahrani ◽  
Khalid R. Hakeem ◽  
Hameed Alsamadany ◽  
El-Sayed M. Desoky ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Gene Expression ◽  
Lipid Peroxidation ◽  
Antioxidative Enzymes ◽  
Irrigation Water ◽  
Foliar Spray ◽  
Cd Stress ◽  
Enzyme Gene ◽  
Maize Plants ◽  
Maize Grain

For maize, the potential preventive role of foliar spraying with an extract derived from maize grain (MEg, 2%), silymarin (Sm, 0.5 mM), or silymarin-enriched MEg (MEg-Sm) in attenuating the stress effects of cadmium (Cd, 0.5 mM) was examined using a completely randomized design layout. Under normal conditions, foliar spraying with MEg, Sm, or MEg-Sm was beneficial (with MEg-Sm preferred) for maize plants, whereas the benefit was more pronounced under Cd stress. The use of Cd through irrigation water decreased plant growth traits, photosynthetic efficiency, including instantaneous carboxylation efficiency, Fv/Fm, and pigment contents, and hormonal contents (e.g., auxin, gibberellins, cytokinins including trans-zeatin, and salicylic acid). These undesired findings were due to an increase in Cd content, leading to increased levels of oxidative stress (O2•− and H2O2), ionic leakage, and lipid peroxidation. Therefore, this damage resulted in an increase in the activities of nonenzymatic antioxidants, Sm, antioxidative enzymes, and enzyme gene expression. However, under Cd stress, although foliar spray with MEg or Sm had better findings than control, MEg-Sm had better findings than MEg or Sm. Application of MEg-Sm greatly increased photosynthesis efficiency, restored hormonal homeostasis, and further increased the activities of various antioxidants, Sm, antioxidative enzymes, and enzyme gene expression. These desired findings were due to the suppression of the Cd content, and thus the levels of O2•−, H2O2, ionic leakage, and lipid peroxidation, which were positively reflected in the growth and accumulation of dry matter in maize plants. The data obtained in this study recommend applying silymarin-enriched maize grain extract (MEg-Sm at 0.24 g Sm L−1 of MEg) as a spray solution to maize plants when exposed to excess Cd in soil or irrigation water.

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