Evaluation of immune responses and oxidative stress in donkeys: immunological studies provoked by Parascaris equorum infection

This review summarizes our current knowledge on the innate and adaptive immune responses induced by hepatitis C virus, and on the genetic polymorphisms that may determine the outcome of the disease. In addition, the authors discuss the role of reactive oxygen species and oxidative stress in hepatitis C virus-related pathogenic processess, such as hepatitis, fibrosis, hepatocellular carcinoma, steatosis and insulin resistance. Orv. Hetil., 2015, 156(47), 1898–1903.

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The role of inflammation and oxidative stress in cardiovascular pathology

Bukovinian Medical Herald ◽

10.24061/2413-0737.xvii.1.65.2013.38 ◽

2013 ◽

Vol 17 (1 (65)) ◽

pp. 156-162

Author(s):

T. V. Talayeva ◽

V. V. Shishkin ◽

L. L. Vavilova

Keyword(s):

Oxidative Stress ◽

Immune Responses ◽

Arterial Hypertension ◽

Vascular Wall ◽

Adaptive Immune Responses ◽

Cardiovascular Pathology ◽

Immune Systems ◽

Adaptive Immune ◽

And Oxidative Stress

The paper is devoted to an analysis of the problem of the significance and mechanisms of inflammation and oxidative stress participation in the development of cardiovascular pathology, first of all – in heart and vascular wall damaging and remodeling and in the development of arterial hypertension. An interrelation is traced between the reninangiotensin, sympathoadrenal and immune systems in the development of oxidative stress as a component of innate and adaptive immune responses.

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Resveratrol as an Adjunctive Therapy for Excessive Oxidative Stress in Aging COVID-19 Patients

Antioxidants ◽

10.3390/antiox10091440 ◽

2021 ◽

Vol 10 (9) ◽

pp. 1440

Author(s):

Min-Tser Liao ◽

Chia-Chao Wu ◽

Shu-Fang Vivienne Wu ◽

Mei-Chen Lee ◽

Wan-Chung Hu ◽

...

Keyword(s):

Oxidative Stress ◽

Immune Responses ◽

Viral Infections ◽

Healthcare Systems ◽

Biological Aging ◽

Interferon Production ◽

Adaptive Immune ◽

Age Related ◽

The Impact ◽

And Oxidative Stress

The coronavirus disease 2019 (COVID-19) pandemic continues to burden healthcare systems worldwide. COVID-19 symptoms are highly heterogeneous, and the patient may be asymptomatic or may present with mild to severe or fatal symptoms. Factors, such as age, sex, and comorbidities, are key determinants of illness severity and progression. Aging is accompanied by multiple deficiencies in interferon production by dendritic cells or macrophages in response to viral infections, resulting in dysregulation of inflammatory immune responses and excess oxidative stress. Age-related dysregulation of immune function may cause a more obvious pathophysiological response to SARS-CoV-2 infection in elderly patients and may accelerate the risk of biological aging, even after recovery. For more favorable treatment outcomes, inhibiting viral replication and dampening inflammatory and oxidative responses before induction of an overt cytokine storm is crucial. Resveratrol is a potent antioxidant with antiviral activity. Herein, we describe the reasons for impaired interferon production, owing to aging, and the impact of aging on innate and adaptive immune responses to infection, which leads to inflammation distress and immunosuppression, thereby causing fulminant disease. Additionally, the molecular mechanism by which resveratrol could reverse a state of excessive basal inflammatory and oxidative stress and low antiviral immunity is discussed.

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Th1/Th2 immune responses and oxidative stress in caprine flea allergy dermatitis

Parasite Immunology ◽

10.1111/pim.12500 ◽

2017 ◽

Vol 39 (12) ◽

pp. e12500 ◽

Cited By ~ 4

Author(s):

Y. Ajith ◽

U. Dimri ◽

A. Gopalakrishnan ◽

E. Madhesh ◽

R. Jhambh ◽

...

Keyword(s):

Oxidative Stress ◽

Immune Responses ◽

Flea Allergy Dermatitis ◽

Flea Allergy ◽

And Oxidative Stress

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Impacts of heat stress on immune responses and oxidative stress in farm animals and nutritional strategies for amelioration

International Journal of Biometeorology ◽

10.1007/s00484-021-02083-3 ◽

2021 ◽

Author(s):

Surinder S. Chauhan ◽

V. P. Rashamol ◽

M. Bagath ◽

Veerasamy Sejian ◽

Frank R. Dunshea

Keyword(s):

Oxidative Stress ◽

Heat Stress ◽

Immune Responses ◽

Farm Animals ◽

Nutritional Strategies ◽

And Oxidative Stress

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Bioaccumulation, Oxidative Stress, Immune Responses in Channa Argus Exposure to Waterborne Hexavalent Chromium

10.21203/rs.3.rs-633529/v1 ◽

2021 ◽

Author(s):

Jia-hua du ◽

Zhe Yu ◽

Jun-liang Zhao ◽

Zhi-hui Bai ◽

Ze-hao Guo ◽

...

Keyword(s):

Oxidative Stress ◽

Immune Response ◽

Immune Responses ◽

Hexavalent Chromium ◽

Biochemical Parameters ◽

Immunoglobulin M ◽

Environmental Toxicants ◽

The World ◽

Channa Argus ◽

And Oxidative Stress

Abstract Hexavalent chromium (Cr (VI)) is a very common and harmful heavy metal pollutant in the world. However, the responses of Cr (VI) to aquatic environmental toxicants have not been well described. In this study, we evaluated the waterborne Cr (VI) [ 0 mg/L (C1), 0.5 mg/L (C2), 1 mg/L (C3), 2 mg/L (C4)] exposed chronically to Channa argus. After 14 and 28 days, we measured biochemical parameters, Cr (VI) accumulation, antioxidant activity and immune response in the serum, liver and gill, respectively. Our results shown that Cr (VI) accumulation will occur in certain tissues as the time of exposure in water prolongs, and the biochemical parameters in the serum will increase. Antioxidant enzymes (catalase, superoxide dismutase and glutathione peroxidase) gradually decreased with the increasing time of Cr (VI) concentration, while the malondialdehyde concentration increases. In addition, in the immune response, cortisol, aminotransferase (ALT), aspartate aminotransferases (AST), alkaline phosphatase (AKP), immunoglobulin M increase, but lysozyme decrease. These results indicated that exposure to waterborne Cr (VI) can exert adverse effects in C. argus by inducing Cr (VI) accumulation, immune responses and oxidative stress.

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