The effect of sleep duration and sleep quality on hypertension in middle-aged and older Chinese: the Dongfeng-Tongji Cohort Study

Aims This study aimed to evaluate the relationship between sleep duration, sleep quality and hyperlipidemia in middle-aged and older Chinese. Methods We included 20,712 individuals at baseline from September 2008 to June 2010, and they were followed-up until October 2013. Hyperlipidemia was defined according to the Chinese guidelines on the prevention and treatment of dyslipidemia in adults. Sleep duration was self-reported and sleep quality was evaluated with a questionnaire that was designed according to the Pittsburgh Sleep Quality Index. Logistic regression and Cox proportional hazard models were conducted to explore the associations. Results In the cross-sectional analyses, longer sleep duration (≥10 h) was significantly associated with higher prevalence of hyperlipidemia (odds ratio (OR) = 1.17, 95% confidence interval (CI) = 1.02–1.35) after adjusting for potential confounders. The ORs of hyperlipidemia were significantly elevated among participants with impaired sleep quality (OR = 1.14, 95% CI = 1.08–1.22) and poor sleep quality (OR = 1.20, 95% CI = 1.08–1.34) when compared to those with good sleep quality. In the longitudinal analyses, compared to participants with a sleep duration of 7–<8 h, those with a sleep duration of 9–<10 h (hazard ratio (HR) = 1.19, 95% CI = 1.04–1.35) and ≥10 h (HR = 1.27, 95% CI = 1.02–1.58) showed significantly higher risk of hyperlipidemia after adjusting for potential confounders. However, no statistically significant association was found between impaired or poor sleep quality and hyperlipidemia. Conclusions Longer sleep duration was significantly associated with higher risk of hyperlipidemia. Impaired or poor sleep quality were associated with elevated prevalence of hyperlipidemia, but not with the incidence of hyperlipidemia.

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Association between nighttime sleep duration, sleep timing and falls among middle-aged and older Chinese population: A cross-sectional analysis from the Dongfeng-Tongji cohort study, China

Geriatrics and Gerontology International ◽

10.1111/ggi.12984 ◽

2017 ◽

Vol 17 (11) ◽

pp. 1886-1892

Author(s):

Yi Wang ◽

Wending Li ◽

Lijun Shen ◽

Lulu Song ◽

Hui Li ◽

...

Keyword(s):

Cohort Study ◽

Sleep Duration ◽

Chinese Population ◽

Middle Aged ◽

Cross Sectional ◽

Sleep Timing ◽

Cross Sectional Analysis ◽

Older Chinese ◽

Nighttime Sleep ◽

Sectional Analysis

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Daily sleep duration and risk of metabolic syndrome among middle-aged and older Chinese adults: cross-sectional evidence from the Dongfeng–Tongji cohort study

BMC Public Health ◽

10.1186/s12889-015-1521-z ◽

2015 ◽

Vol 15 (1) ◽

Cited By ~ 17

Author(s):

Jing Wu ◽

Guiqiang Xu ◽

Lijun Shen ◽

Yanmei Zhang ◽

Lulu Song ◽

...

Keyword(s):

Metabolic Syndrome ◽

Cohort Study ◽

Sleep Duration ◽

Middle Aged ◽

Chinese Adults ◽

Cross Sectional ◽

Older Chinese ◽

Older Chinese Adults

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Association between parity and obesity patterns in a middle-aged and older Chinese population: a cross-sectional analysis in the Tongji-Dongfeng cohort study

Nutrition & Metabolism ◽

10.1186/s12986-016-0133-7 ◽

2016 ◽

Vol 13 (1) ◽

Cited By ~ 12

Author(s):

Wending Li ◽

Yi Wang ◽

Lijun Shen ◽

Lulu Song ◽

Hui Li ◽

...

Keyword(s):

Cohort Study ◽

Chinese Population ◽

Middle Aged ◽

Cross Sectional ◽

Cross Sectional Analysis ◽

Older Chinese ◽

Sectional Analysis

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Adiposity change and mortality in middle-aged to older Chinese: an 8-year follow-up of the Guangzhou Biobank Cohort Study

BMJ Open ◽

10.1136/bmjopen-2020-039239 ◽

2020 ◽

Vol 10 (12) ◽

pp. e039239

Author(s):

Ying Yue Huang ◽

Chao Qiang Jiang ◽

Lin Xu ◽

Wei Sen Zhang ◽

Feng Zhu ◽

...

Keyword(s):

Cohort Study ◽

Outcome Measures ◽

Mortality Risk ◽

Cancer Mortality ◽

Secondary Outcome ◽

Middle Aged ◽

All Cause Mortality ◽

Older Chinese ◽

Cvd Mortality

ObjectiveTo examine the associations of change in body mass index (BMI) and waist circumference (WC) over an average of 4 years with subsequent mortality risk in middle-aged to older Chinese.DesignProspective cohort study based on the Guangzhou Biobank Cohort Study.SettingCommunity-based sample.Participants17 773 participants (12 956 women and 4817 men) aged 50+ years.Primary and secondary outcome measuresPrimary outcome measure was all-cause mortality. Secondary outcome measures were cardiovascular disease (CVD) and cancer mortality. Causes of death were obtained via record linkage, and coded according to the International Classification of Diseases (tenth revision).Results1424 deaths (53.4% women) occurred in the 17 773 participants (mean age 61.2, SD 6.8 years) during an average follow-up of 7.8 (SD=1.5) years, and 97.7% of participants did not have an intention of weight loss . Compared with participants with stable BMI, participants with BMI loss (>5%), but not gain, had a higher risk of all-cause mortality (HR=1.49, 95% CI 1.31 to 1.71), which was greatest in those who were underweight (HR=2.45, 95% CI 1.31 to 4.59). Similar patterns were found for WC. In contrast, for participants with a BMI of ≥27.5 kg/m2, BMI gain, versus stable BMI, was associated with 89% higher risk of all-cause mortality (HR=1.89, 95% CI 1.25 to 2.88), 72% higher risk of CVD mortality (HR=1.72, 95% CI 0.80 to 3.72) and 2.27-fold risk of cancer mortality (HR=2.27, 95% CI 1.26 to 4.10).ConclusionIn older people, unintentional BMI/WC loss, especially in those who were underweight was associated with higher mortality risk. However, BMI gain in those with obesity showed excess risks of all-cause and cancer mortality, but not CVD mortality. Frequent monitoring of changes in body size can be used as an early warning for timely clinical investigations and interventions and is important to inform appropriate health management in older Chinese.

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