Proximal Versus Distal Gastric Bypass In Patients With Body Mass Index 50 to 60: A Double-Blind, Randomized Clinical Trial

2015 ◽  
Vol 11 (6) ◽  
pp. S1-S2 ◽  
Author(s):  
Hilde Risstad ◽  
Marius Svanevik ◽  
Jon A Kristinsson ◽  
Jøran Hjelmesæth ◽  
Erlend T. Aasheim ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Body Mass Index ◽  
Gastric Bypass ◽  
Randomized Clinical Trial ◽  
Body Mass ◽  
Double Blind ◽  
Distal Gastric Bypass

scholarly journals The Effect of L-Carnitine Supplementation on Weight and Body Composition in Women with Polycystic Ovary Syndrome: A Double-Blind Randomized Clinical Trial

2020 ◽  
Author(s):  
Fatemeh Pakravanfar ◽  
Akram Ghadiri-Anari ◽  
Azadeh Nadjarzadeh ◽  
Hossein Fallahzadeh ◽  
Mahdieh Hosseinzadeh
Keyword(s):  
Clinical Trial ◽  
Body Mass Index ◽  
Body Composition ◽  
Waist Circumference ◽  
Randomized Clinical Trial ◽  
Body Mass ◽  
Fat Mass ◽  
Hip Circumference ◽  
Double Blind ◽  
Significant Difference

Background: Polycystic ovarian syndrome (PCOS), one of the most common causes of endocrine disorders with irregular menstruation, is accompanied by an increase in androgen and polycystic ovarian. The aim of this study was to evaluate the effect of weight loss regimen with and without supplementation. L-carnitine affects lipid profile, insulin, and hormone resistance indices. Methods: This double-blind randomized clinical trial was conducted over women within the age range of 18 to 45 years, who referred to Yazd Diabetes Center in 2019. The participants were divided into the experimental and control groups. The intervention group received 1000 mg L-carnitine (LG = 28) and the placebo group (PG = 28) received the placebo daily. All people followed a low celery diet for 12 weeks. Anthropometric indices and body composition (weight, body mass index, waist circumference, hip circumference, fat mass, and free fat mass) were measured prior to and after the intervention. Data analysis was performed using SPSS software version 22. The independent sample t-test was used to compare the mean changes between the LG and PG. Results: At the end of the study period, patients treated with L-carnitine showed a significant decrease in waist circumference compared to the PG (change: -1 ± 3.15, P = 0.001) and no significant difference was observed between the two groups in terms of other anthropometrics indices and body composition including fat mass, body mass index, and hip circumference (P > 0.05). Conclusion: The present study showed that 1000 mg oral L-carnitine had no significant effect on body weight, body mass index, body composition, and hip circumference, but had a significant effect on waist circumference size.

scholarly journals The effects of steamed ginger ethanolic extract on weight and body fat loss: a randomized, double-blind, placebo-controlled clinical trial

2019 ◽  
Vol 29 (2) ◽  
pp. 265-273 ◽  
Author(s):  
Soo-Hyun Park ◽  
Su-Jin Jung ◽  
Eun-Kyung Choi ◽  
Ki-Chan Ha ◽  
Hyang-Im Baek ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Body Mass Index ◽  
Body Weight ◽  
Body Mass ◽  
Body Fat ◽  
Ethanolic Extract ◽  
Controlled Clinical Trial ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Fat Loss

Abstract Steamed ginger ethanolic extract (SGE) is a product with a high 6-shogaol contents and is thought to be more potent than other ginger products. We conducted a 12-week, randomized, double-blind, placebo-controlled clinical trial to determine the effects of SGE on weight and body fat loss. Eighty healthy obese participants were recruited and randomly divided into the SGE and placebo groups. The outcome measures comprised indicators of efficacy (body weight, body mass index, body composition, and blood markers) and safety. Following the supplementation period, mean body weight, body mass index, and body fat level were significantly lower in the SGE group than in the placebo group. No clinically significant changes were observed for any safety parameter. These results suggest that SGE is a potent anti-obesity agent that does not cause significant side effects. Therefore, SGE supplementation combined with lifestyle modification could be effective in the management of body weight and fat mass.

Cesarean wound closure in body mass index 40 or greater comparing suture to staples: a randomized clinical trial

2020 ◽  
pp. 100271
Author(s):  
Rachel L. Rodel ◽  
Kendra M. Gray ◽  
Trevor E. Quiner ◽  
Ana Bodea Braescu ◽  
Richard Gerkin ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Body Mass Index ◽  
Randomized Clinical Trial ◽  
Body Mass ◽  
Wound Closure

scholarly journals Effect of school-based body mass index reporting in California public schools: a randomized clinical trial

2021 ◽  
Author(s):  
Kristine A Madsen ◽  
Hannah R Thompson ◽  
Jennifer Linchey ◽  
Lorrene D Ritchie ◽  
Shalika Gupta ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Body Mass Index ◽  
Public Schools ◽  
Randomized Clinical Trial ◽  
Body Mass ◽  
School Based ◽  
California Public Schools

scholarly journals Evaluation of the Scopinaro Modified Technique in the Surgical Treatment of Obesity Compared to the Classic Scopinaro Surgery – Results after an 18-Month Randomized Clinical Trial

2019 ◽  
Vol 12 (02) ◽  
pp. 071-080
Author(s):  
Paulo Reis Esselin de Melo ◽  
Thonya Cruz Braga ◽  
Neusa Dias de Moura ◽  
João Carlos Gonçalves Junior ◽  
Marcos Vinicius Macedo de Oliveira ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Body Mass Index ◽  
Surgical Treatment ◽  
Randomized Clinical Trial ◽  
Body Mass ◽  
Modified Technique ◽  
Treatment Of Obesity ◽  
Surgical Treatment Of Obesity

Resumo Objetivo Avaliar se a cirurgia de Scopinaro modificada é tão eficaz e segura quanto a cirurgia de Scopinaro clássica para reduzir o excesso de peso, controlar as comorbidades, e avaliar o surgimento de intercorrências clínicas e nutricionais, caso elas ocorram. Métodos O estudo teve 28 participantes obesos, que foram randomizados para a realização de um dos procedimentos cirúrgicos, e acompanhados por uma equipe multiprofissional em saúde para avaliar o impacto das cirurgias no tratamento da obesidade. Foram observadas as seguintes variáveis: comorbidades, e intercorrências clínicas e nutricionais. O protocolo de pesquisa foi aprovado pelo Comitê de Ética em Pesquisa das Faculdades Integradas Pitágoras de Montes Claros (CAAE 26919414.9.0000.5109). Todos os participantes da pesquisa assinaram o termo de consentimento livre e esclarecido. Resultados A média do índice de massa corporal (IMC) pré-cirurgia do grupo Scopinaro clássica e do grupo Scopinaro modificada foi de, respectivamente, 46,89 kg/m2 e 43,22 kg/m2. Após 540 dias da realização das cirurgias, esses valores foram reduzidos para 32,16 kg/m2 e 28,79 kg/m2. A avaliação da porcentagem de IMC perdido (percentage of excess body mass index lost, %EBL, em inglês) no período comprovou o sucesso cirúrgico, com valores de 67,33% para a cirurgia de Scopinaro clássica, e de 80,37% para a cirurgia de Scopinaro modificada. Ocorreu controle das comorbidades, bem como melhora geral do quadro laboratorial para a maioria dos participantes submetidos a quaisquer das duas técnicas. Flatulência e diarreia constituíram as intercorrências clínicas predominantemente encontradas em ambos procedimentos. Conclusão A cirurgia de Scopinaro modificada mostrou-se tão eficaz e segura quanto a cirurgia de Scopinaro clássica na redução de peso e controle das comorbidades, apresentando ainda a possibilidade de acesso endoscópio a todo o estômago e duodeno, reversibilidade cirúrgica, e conversão em outro procedimento cirúrgico.

Potential roles of Helicobacter pylori treatment, body mass index and waist circumference in the causation of erosive esophagitis: a randomized clinical trial (HEROES-GERD)

2019 ◽  
Vol 44 (1) ◽  
pp. 147-158
Author(s):  
Felipe Mazzoleni ◽  
Luiz Edmundo Mazzoleni ◽  
Carlos Fernando de Magalhães Francesconi ◽  
Guilherme Becker Sander ◽  
Pâmela Schitz Von Reisswitz ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Body Mass Index ◽  
Helicobacter Pylori ◽  
Waist Circumference ◽  
Randomized Clinical Trial ◽  
Body Mass ◽  
Erosive Esophagitis ◽  
Helicobacter Pylori Treatment

Effects of flaxseed on blood pressure, body mass index, and total cholesterol in hypertensive patients: A randomized clinical trial

EXPLORE ◽  
2021 ◽  
Author(s):  
Tahereh Toulabi ◽  
Masomeh Yarahmadi ◽  
Fatemeh Goudarzi ◽  
Farzad Ebrahimzadeh ◽  
Amir Momenizadeh ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Clinical Trial ◽  
Body Mass Index ◽  
Total Cholesterol ◽  
Randomized Clinical Trial ◽  
Body Mass ◽  
Hypertensive Patients

scholarly journals Effects of Vitamin D Supplementation on Female Vitamin D Deficient Teenagers: A Randomized Clinical Trial

2020 ◽  
Author(s):  
Salma Ahi ◽  
Fatemeh Gholami ◽  
Naser Hatami ◽  
Fatemeh Golabi
Keyword(s):  
Clinical Trial ◽  
Body Mass Index ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Randomized Clinical Trial ◽  
Body Mass ◽  
Anthropometric Indices ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
Before And After

Abstract Background: Vitamin D deficiency is one of the most prevalent disorders worldwide. Considering the magnitude of growth in adolescence, the aim of this study was to ascertain the prevalence of vitamin D deficiency and discover the association between anthropometric indices and vitamin D levels and the effect of vitamin D treatment on anthropometric indices in adolescent girls. Method: we performed this randomized clinical trial study (approved by Iranian Registry of Clinical Trials with code of IRCT20200615047785N2) conducting 313 high school girl students in a random cluster sampling from Jahrom city schools. Blood samples were collected from participants to determine the serum level (OH) D25. We divided vitamin D deficient patients into two groups: control who received placebo (n=150) and intervention group (n=150) who were prescribed one tablet of 50,000 units of vitamin D per week for eight weeks. Anthropometric indices of participants were measured before and after the intervention. Datas were analyzed by SPSS software version 19.Results: The prevalence of vitamin D deficiency was 95%. Body mass index had no significant difference before the intervention in both groups (P = 0.76). After intervention in the case group, body mass index increased significantly (P = 0.01), but there was no significant difference in the control group after treatment (P = 0.42). There was no significant difference in waist circumference, height and weight before and after the intervention in both groups (P > 0.05). There was also a weak but significant correlation between height, weight, and baseline 25OHD levels of participants.Conclusion: The results of this study showed that there is a reverse and significant relationship between height and weight index with 25OHD. Further monitoring and prolonged studies with extended follow ups might improve the anthropometric parameters after treatment.

scholarly journals Pengaruh Jamu Obesitas terhadap Indeks Massa Tubuh, Lingkar Perut, dan Lingkar Lengan dibandingkan dengan Orlistat dan Evaluasi Keamanannya

2018 ◽  
Vol 46 (3) ◽  
pp. 177-182
Author(s):  
Danang Ardiyanto
Keyword(s):  
Clinical Trial ◽  
Body Mass Index ◽  
Randomized Clinical Trial ◽  
Body Mass ◽  
Open Label ◽  
Upper Arm ◽  
Safe Alternative ◽  
Arm Circumference ◽  
Sonchus Arvensis ◽  
Mid Upper Arm Circumference

Obesity could be a risk factor for other diseases, especially degenerative diseases. The prevalence of obesity is beginning to elevate at developing countries. Indonesia has some traditional ingredients that can be used for alternatives in obesity problems. But there isnot valid evidence for the efficacy and safety of traditional herbs. This study was conducted to evaluate efficacy of Jamu formulation in comparison with orlistat and evaluate its safety. Jamu formula contains Guazuma ulmifolia dried leaves, Murraya paniculata dried leaves, Rheum officinale dried roots, and Sonchus arvensis dried leaves. The present study was an randomized clinical trial open label undertaken in 242 subjects of obesity for 56 days. The Jamu group received a glass twice daily and orlistat group received a capsule twice daily. Efficacy was assessed by the changes in body mass index, waist and mid-upper arm circumference. Safety was evaluated by SGOT, SGPT, ureum, dan creatinine. There was a significant decrease (p<0,05) in body mass index, waist and mid-upper arm circumference after intervention in both group. Changes of those parameters were not significantly different (p>0,05) between both groups. No significant alteration was seen in most of the SGOT, SGPT, ureum, dan creatinine in Jamu formula groups. This study showed Jamu formula was an equally effective, but safe alternative for obesity management.   Abstrak   Obesitas dapat menjadi faktor resiko penyakit lain khususnya penyakit degeneratif. Prevalensi obesitas mulai mengalamai peningkatan di negara berkembang. Indonesia memiliki beberapa ramuan tradisional yang dapat digunakan untuk alternatif dalam masalah obesitas. Namun belum ada bukti yang kuat mengenai khasiat dan keamanan dari ramuan tradisional yang ada. Tujuan penelitian ini untuk mengetahui manfaat dan keamanan ramuan jamu yang terdiri dari simplisia daun jati belanda, daun kemuning, akar kelembak, dan daun tempuyung dibandingkan orlistat. Penelitian ini menggunakan randomized clinical trial (RCT) open label dengan 242 subyek selama 56 hari.. Kelompok jamu diberikan segelas jamu 2 kali sehari, sedangkan kelompok orlistat diberikan satu kapsul sehari dua kali. Parameter yang digunakan untuk mengevaluasi khasiat formula jamu dan orlistat adalah indeks masa tubuh (IMT), lingkar perut (LP), lingkar lengan atas (LLA). Sedangkan penilaian keamanan digunakan parameter SGOT, SGPT, BUN, dan kreatinin. Pemberian jamu dan orlistat dapat menurunkan IMT, LP, LLA secara bermakna (p<0,05) jika dibandingkan dengan hari ke-0. Penurunan IMT, LP, LLA kelompok jamu dibandingkan orlistat dapat dikatakan setara (p>0,05). Kelompok jamu menujukkan nilai SGOT, SGPT, ureum, dan kreatinin dalam rentang normal. Penelitian ini menunjukkan bahwa ramuan jamu obesitas secara klinis, khasiatnya sebanding dengan orlistat dan aman setelah intervensi selama 56 hari.

Sign in / Sign up

Export Citation Format

Share Document