scholarly journals Acute oral toxicity evaluation of aqueous ethanolic extract of Saccharum munja Roxb. roots in albino mice as per OECD 425 TG

2017 ◽  
Vol 4 ◽  
pp. 580-585 ◽  
Author(s):  
Uzma Saleem ◽  
Sadia Amin ◽  
Bashir Ahmad ◽  
Haroon Azeem ◽  
Fareeha Anwar ◽  
...  
2019 ◽  
Vol 6 ◽  
pp. 426-430 ◽  
Author(s):  
Luksamee Worasuttayangkurn ◽  
Watanyoo Nakareangrit ◽  
Jackapun Kwangjai ◽  
Pishyaporn Sritangos ◽  
Nanthanit Pholphana ◽  
...  

2018 ◽  
Vol 24 (1) ◽  
pp. 23-30 ◽  
Author(s):  
Mohammadmehdi Hassanzadeh-Taheri ◽  
Mehran Hosseini ◽  
Mojtaba Salimi ◽  
Hesam Moodi ◽  
Davood Dorranpour

2019 ◽  
Vol Volume 14 ◽  
pp. 10035-10046 ◽  
Author(s):  
Muhammad Ahmad Mahmood ◽  
Asadullah Madni ◽  
Mubashar Rehman ◽  
Muhammad Abdur Rahim ◽  
Abdul Jabar

Author(s):  
Savin Chanthala Ganapathi ◽  
Rajendra Holla ◽  
Shivaraja Shankara Ym ◽  
Ravi Mundugaru

Objective: To study the acute oral toxicity of ethanolic extract of Actinoscirpus grossus (L.f.) Goetgh. and D.A. Simpson in Wistar albino rats.Methods: Ethanolic extract of the plant was assessed for single dose acute toxicity by employing Organisation for Economic Co-Operation and Development(OECD) guidelines 425 using Acute Oral Toxicity(AOT) software. The dosed (up or down as per the requirement) rats were observed for 14 days for general appearance, behavior, mortality, and necropsy. A total of 5 healthy female rats of body weight 225±25 g were used.Results: The test substance did not produce any mortality up to the dose of 2000 mg/kg per oral.Conclusion: Test substance is without any toxic potential even at the dose of 2000 mg/kg in animals and the Lethal Dose (LD50) value of A. grossus (L.f.) Goetgh. and D.A. Simpson was found to be more than 2000 mg/kg body weight.


1993 ◽  
Vol 12 (6) ◽  
pp. 584-585
Author(s):  
L. D. Brown ◽  
D. W. Korte ◽  
J. D. Justus ◽  
C. R. Wheeler ◽  
E. W. Morgan ◽  
...  

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