Acute oral toxicity evaluation of antihyperlipidemic polyherbal preparation comprising of aqueous extracts in female sprague dawley rats as per OECD 425 TG.

Author(s):  
Saad Alkahtani ◽  
Md Saquib Hasnain ◽  
Hamzah Algamdy ◽  
Nada H. Aljarba ◽  
Abdullah AlKahtane

Food Research ◽  
2021 ◽  
Vol 5 (1) ◽  
pp. 390-393
Author(s):  
Rohini J. ◽  
Rabeta M.S. ◽  
Wan Ezumi M.F.

In this study, the extract of Ocimum tenuiflorum was formulated to promote wound healing and no acute toxicity study has been reported on this type of formulation. Acute oral toxicity results of the rats after administration of 5000 mg/kg body weight (BW) formulation showed no toxic effects and behavioural changes of the rats after 14 days of observation. On day 14, the rats were anaesthetized to collect the vital organs for histopathological examination. The microscopy study of the visceral organs of wound healing powder group shows no sign of toxicity in comparison to untreated rats organs. In conclusion, the result of the acute oral toxicity test of wound healing drink showed no sign of toxicity, as corroborated by a histopathological study.


2020 ◽  
Vol 9 (4) ◽  
pp. 265-269
Author(s):  
Toonse Mudimba ◽  
◽  
James Mbaria ◽  
Timothy Maitho ◽  
Tafadzwa Taderera ◽  
...  

2015 ◽  
Vol 7 (1) ◽  
pp. 38 ◽  
Author(s):  
MallikarjunaRao Pichika ◽  
MadhuKatyayani Balijepalli ◽  
Velan Suppaiah ◽  
An-me Chin ◽  
AyubaSunday Buru ◽  
...  

2016 ◽  
Vol 10 (3) ◽  
pp. 261-264 ◽  
Author(s):  
F. Rahmayanti ◽  
D.F. Suniarti ◽  
Z.A. Mas`ud ◽  
B.M. Bachtiar ◽  
Y.S. Wimardhani ◽  
...  

2015 ◽  
Vol 28 (4) ◽  
pp. 371-381
Author(s):  
Min-Kyeoung Kim ◽  
Ji Sun Lee ◽  
Yeong Chul Park ◽  
Sun Mi Choi ◽  
Sanghun Lee

2016 ◽  
Vol 7 (6) ◽  
pp. 103-109 ◽  
Author(s):  
Arakere C Udayashankar ◽  
Sollepura B Rajini ◽  
Murali Nandhini ◽  
Y S Suhas ◽  
Siddapura R Niranjana ◽  
...  

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