scholarly journals Acute oral toxicity evaluation of Andrographis paniculata-standardized first true leaf ethanolic extract

2019 ◽  
Vol 6 ◽  
pp. 426-430 ◽  
Author(s):  
Luksamee Worasuttayangkurn ◽  
Watanyoo Nakareangrit ◽  
Jackapun Kwangjai ◽  
Pishyaporn Sritangos ◽  
Nanthanit Pholphana ◽  
...  
Keyword(s):  
Ethanolic Extract ◽  
Andrographis Paniculata ◽  
Acute Oral Toxicity ◽  
Toxicity Evaluation ◽  
Oral Toxicity ◽  
True Leaf

scholarly journals Acute oral toxicity evaluation of aqueous ethanolic extract of Saccharum munja Roxb. roots in albino mice as per OECD 425 TG

2017 ◽  
Vol 4 ◽  
pp. 580-585 ◽  
Author(s):  
Uzma Saleem ◽  
Sadia Amin ◽  
Bashir Ahmad ◽  
Haroon Azeem ◽  
Fareeha Anwar ◽  
...  
Keyword(s):  
Ethanolic Extract ◽  
Acute Oral Toxicity ◽  
Toxicity Evaluation ◽  
Oral Toxicity ◽  
Aqueous Ethanolic Extract ◽  
Albino Mice ◽  
Saccharum Munja

scholarly journals Acute and Sub-Acute Oral Toxicity Evaluation of Astragalus hamosus Seedpod Ethanolic Extract in Wistar Rats

2018 ◽  
Vol 24 (1) ◽  
pp. 23-30 ◽  
Author(s):  
Mohammadmehdi Hassanzadeh-Taheri ◽  
Mehran Hosseini ◽  
Mojtaba Salimi ◽  
Hesam Moodi ◽  
Davood Dorranpour
Keyword(s):  
Wistar Rats ◽  
Ethanolic Extract ◽  
Acute Oral Toxicity ◽  
Toxicity Evaluation ◽  
Oral Toxicity

scholarly journals Ionically Cross-Linked Chitosan Nanoparticles for Sustained Delivery of Docetaxel: Fabrication, Post-Formulation and Acute Oral Toxicity Evaluation

2019 ◽  
Vol Volume 14 ◽  
pp. 10035-10046 ◽  
Author(s):  
Muhammad Ahmad Mahmood ◽  
Asadullah Madni ◽  
Mubashar Rehman ◽  
Muhammad Abdur Rahim ◽  
Abdul Jabar
Keyword(s):  
Chitosan Nanoparticles ◽  
Sustained Delivery ◽  
Acute Oral Toxicity ◽  
Toxicity Evaluation ◽  
Oral Toxicity

scholarly journals ACUTE ORAL TOXICITY STUDY OF ETHANOLIC EXTRACT OF ACTINOSCIRPUS GROSSUS (L.F.) GOETGH. AND D.A. SIMPSON

2018 ◽  
Vol 11 (7) ◽  
pp. 321
Author(s):  
Savin Chanthala Ganapathi ◽  
Rajendra Holla ◽  
Shivaraja Shankara Ym ◽  
Ravi Mundugaru
Keyword(s):  
Body Weight ◽  
Lethal Dose ◽  
Ethanolic Extract ◽  
Female Rats ◽  
Test Substance ◽  
Acute Oral Toxicity ◽  
Oral Toxicity ◽  
Healthy Female ◽  
Ld50 Value ◽  
Toxic Potential

Objective: To study the acute oral toxicity of ethanolic extract of Actinoscirpus grossus (L.f.) Goetgh. and D.A. Simpson in Wistar albino rats.Methods: Ethanolic extract of the plant was assessed for single dose acute toxicity by employing Organisation for Economic Co-Operation and Development(OECD) guidelines 425 using Acute Oral Toxicity(AOT) software. The dosed (up or down as per the requirement) rats were observed for 14 days for general appearance, behavior, mortality, and necropsy. A total of 5 healthy female rats of body weight 225±25 g were used.Results: The test substance did not produce any mortality up to the dose of 2000 mg/kg per oral.Conclusion: Test substance is without any toxic potential even at the dose of 2000 mg/kg in animals and the Lethal Dose (LD50) value of A. grossus (L.f.) Goetgh. and D.A. Simpson was found to be more than 2000 mg/kg body weight.

Acute Oral Toxicity Evaluation of JA-2 Solid Propellant

1993 ◽  
Vol 12 (6) ◽  
pp. 584-585
Author(s):  
L. D. Brown ◽  
D. W. Korte ◽  
J. D. Justus ◽  
C. R. Wheeler ◽  
E. W. Morgan ◽  
...  
Keyword(s):  
Solid Propellant ◽  
Acute Oral Toxicity ◽  
Toxicity Evaluation ◽  
Oral Toxicity

scholarly journals Study on Acute Oral Toxicity of Ethanolic Extract of Annonasquamosa Leaves in Mice (Musmusculus)

2018 ◽  
Vol 1 (1) ◽  
pp. 56-63
Author(s):  
Khairunnisa ◽  
Andini Dita Utami ◽  
Marianne
Keyword(s):  
Ethanolic Extract ◽  
Fixed Dose ◽  
Control Group ◽  
Acute Oral Toxicity ◽  
Oral Toxicity ◽  
Hydropic Degeneration ◽  
Treatment Groups ◽  
Dose Method ◽  
Liver And Kidney ◽  
Tubular Dilatation

Abstract. The aims of this study were to determine the potential for acute oral toxicity of ethanolic extract of A.squamosa leaves with LD50 and the histopathological changes in liver and kidney of mice.This research used experimental method as per fixed dose method. The number of animals used in this research were 20 female mice. The study was divided into 2 steps, there were sighting and main studies. The control group was given Na-CMC 0.5%, the treatment groups were given ethanolic extract of A.squamosa leaves with doses of 5, 50, 300,  2,000 and 5,000 mg/kg bw. The results showed that the ethanolic extract of A.squamosa leaves with doses of 2,000 and 5,000 mg/kg bw did not show any toxicity signs. At a dose of 5,000 mg/kg bw caused hydropic degeneration, necrosis hepatocyte, glomerular atrophy, and tubular dilatation.  There was no mortality was observed.It was estimated that LD50 of ethanolic extract of A.squamosa leaves was higher than 5,000 mg/kg bw and the extract were practically non-toxic. Keywords: Acute Toxicity,  Annona squamosa, Ethanolic Extract

scholarly journals Acute oral toxicity evaluation of extracts of Hydrocotyle sibthorpioides in wister albino rats as per OECD 425 TG

2019 ◽  
Vol 6 ◽  
pp. 321-328 ◽  
Author(s):  
Iswar Hazarika ◽  
K.M. Geetha ◽  
P. Sivakami Sundari ◽  
Divya Madhu
Keyword(s):  
Albino Rats ◽  
Acute Oral Toxicity ◽  
Toxicity Evaluation ◽  
Oral Toxicity

Acute Oral Toxicity Evaluation of Some Polyherbal Formulations in Albino Wistar Rats

2008 ◽  
Vol 4 (5) ◽  
pp. 388-392 ◽  
Author(s):  
A.J. Joshua ◽  
K.S. Goudar ◽  
A. Damodaran ◽  
N. Sameera ◽  
A. Amit
Keyword(s):  
Wistar Rats ◽  
Acute Oral Toxicity ◽  
Toxicity Evaluation ◽  
Oral Toxicity
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