Friction and system models are fundamentally coupled. In fact, the success of models in predicting experimental results depends highly on the modeling of friction. This is true at the atomic scale where the nanoscale friction depends on a large set of parameters. This paper presents a novel nanoscale friction model based on the bristle interpretation of single asperity contact. This interpretation is adopted after a review of dynamic friction models representing stick-slip motion in macrotribology literature. The proposed model uses state variables and introduces a generalized bristle deflection. Jumping mechanisms are implemented in order to take into account the instantaneous jumps observed during 2D stick-slip phenomena. The model is dynamic and Lipchitz, which makes it suitable for future control implementation. Friction force microscope scans of a muscovite mica sample were conducted in order to determine numerical values of the different model parameters. The simulated and experimental results are then compared in order to show the efficacy of the proposed model.