Comparative study of the efficacy of the topical application of hydrocortisone, therapeutic ultrasound and phonophoresis on the tissue repair process in rat tendons

2005 ◽  
Vol 31 (3) ◽  
pp. 345-350 ◽  
Author(s):  
Paulo Umeno Koeke ◽  
Nivaldo Antonio Parizotto ◽  
Patrícia Michelassi Carrinho ◽  
Ana Claúdia Bonone Salate
2010 ◽  
Vol 36 (10) ◽  
pp. 1682-1690 ◽  
Author(s):  
Antonio Luiz Martins Maia Filho ◽  
Antonio Balbin Villaverde ◽  
Egberto Munin ◽  
Flávio Aimbire ◽  
Regiane Albertini

2006 ◽  
Vol 24 (6) ◽  
pp. 754-758 ◽  
Author(s):  
Patricia M. Carrinho ◽  
Ana Claudia Muniz Renno ◽  
Paulo Koeke ◽  
Ana Claudia Bonogne Salate ◽  
Nivaldo Antonio Parizotto ◽  
...  

2018 ◽  
Vol 2 (2) ◽  
Author(s):  
Giuseppe Nebbioso ◽  
Ciro Falasconi ◽  
Viviana Nebbioso ◽  
Francesco Petrella

L’insorgenza di infezione su una lesione cutanea cronica determina un arresto del processo di riparazione tessutale e impone l’instaurazione di una terapia antibiotica sistemica che, in una fase iniziale, sarà empirica e, dunque, non scevra di insuccessi. L’utilizzo di antimicrobici con ridotto potere citotossoco/istiolesivo può essere considerata, in molti casi, una valida alternativa per il controllo della carica batterica e dell’infezione locale. L’associazione di antimicrobici a base di poliesanide biguanide, betaina e cadexomero iodico, in molti casi, permette di controllare/ridurre la carica batterica e l’infezione locale fungendo da starter per la ripresa del processo di riparazione tessutale. The onset of infection on a skin ulcer (chronic wound) leads to a halt in the tissue repair process and requires a systemic antibiotic therapy which, at an early stage, will be empirical and, therefore, not free from setbacks. The use of antimicrobials with reduced cytotoxic/histiolesive power can be considered, in many cases, a valid alternative for bacterial burden and local infection control. The combination of antimicrobials based on polystyrene biguanide, betaine and iodine cadexomer, in many cases, allows to control/reduce the bacterial burden and local infection by acting as a starter for the resumption of the tissue repair process.


Author(s):  
Gouri Kalaskar ◽  
Pratik Phansopkar

Aims: To see the effectiveness of supervised exercises and cyriax physiotherapy both including therapeutic ultrasound for improving pain and function in adults with lateral epicondylitis. Study Design: Comparative study- to find out the efficacy of effectiveness of two different interventions for reducing pain and improving function in patients with lateral epicondylitis Place and Duration of Study: Department of Musculoskeletal  Physiotherapy Sciences, Ravi Nair Physiotherapy College, Sawangi (Meghe), Wardha, for 12 months. Methodology: A total of 30 people with lateral epicondylitis (tennis elbow) were selected to take part in a comparative research. Subjects were randomized 1:1 to either (1) supervised exercise programme group, or (2) cyriax physiotherapy group. Over just a 4-week period, three times each week for a sum of 12 sessions, promptly after baseline evaluation and randomization, subjects received static stretching of Extensor Carpi Radialis Brevis followed by eccentric strengthening of the wrist extensors and Therapeutic Ultrasound in supervised exercise programme group. While those in cyriax physiotherapy group received deep transverse friction massage for 10 min immediately followed by Mill’s manipulation and Ultrasound. The study concluded at the 4 weeks. Results: Out of 30 patients half were placed in each group, where p=.0001. Significant increase in mean in the group I and II in pre ad post-test VAS score (4.20±0.77 and 5.20±0.67) and TEFS score pre and post-test (17.33±1.44 and 19.80±1.42). analysis showed significant improvement in both the groups. Conclusion: From the observations and results, the conclusion drawn that there is significant improvement in both the groups but effect of cyriax physiotherapy in the form of deep friction massage and mills manipulation combined with therapeutic ultrasound for improving pain on VAS and function on TEF scale.


2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
M Yamamoto ◽  
H Yasukawa ◽  
J Takahashi ◽  
S Nohara ◽  
T Sasak ◽  
...  

Abstract Background Interleukin-22 (IL-22) is a member of the IL-10 cytokine family, which mainly targets epithelial cells and does not target immune cells. Recently, it has been reported that IL-22 play roles in tissue repair in the skin and the liver; however, role of IL-22 in the process of tissue repair after myocardial infarction (MI) is unknown. Here, we investigated the role of IL-22 in tissue repair process after MI. Methods and results First, we examined the expression of IL-22 and its receptor IL-22RA1 in the wild type (WT) mice by real-time PCR. The expression of IL-22 and IL-22RA1 in the hearts were significantly increased 3 days after MI (p<0.05). To clarify the role of IL-22 in the heart after MI, we produced MI model in the WT mice and IL-22 knockout (KO) mice. We found that the IL-22 KO mice had significantly higher mortality than the WT mice after MI (p<0.05). Approximately 80% of the IL-22 KO mice died with cardiac rupture after MI. The infarct size which was estimated by evans blue dye and triphenyltetrazolium chloride staining at 3 days after MI was comparable between the IL-22 KO mice and the WT mice. Next, we performed real time PCR and PCR array analysis for tissue fibrosis and repair genes. We found that alpha-smooth muscle actin (aSMA), NF-kB, TNF-a and MMP13 (also known as collagenase-3) were significantly increased in the infarct area of IL-22 KO mice compared to WT mice. Immunostaining showed that the myofibroblast marker aSMA positive cells in the border area after MI were markedly higher in the IL-22 KO mice compared with the WT mice (p<0.05). Approximately 70% of cardiac rupture after MI in the IL-22 KO mice were occurred in the infarct area adjacent to the border area. Furthermore, we found aSMA positive cells and MMP13 positive cells around the ruptured site of the heart. Conclusion Thus, IL-22 KO mice exhibit high mortality and increased cardiac rupture after MI. And expression of aSMA and MMP13 were highly expressed in the ruptured site after MI in the IL-22 KO mice. These results suggest that IL-22 may play an important role in the tissue repair process after MI.


2019 ◽  
Vol 4 (1) ◽  
pp. 17-24
Author(s):  
Kesia Maria Mangoni Gonçalves dos Santos ◽  
Maria Elvira Ribeiro Cordeiro ◽  
Mário César da Silva Pereira ◽  
Danillo Barbosa ◽  
André Alexandre Pezzini ◽  
...  

2015 ◽  
Vol 119 (5) ◽  
pp. 505-513 ◽  
Author(s):  
Ronaldo Célio Mariano ◽  
Marina Reis Oliveira ◽  
Leopoldo Cosme Silva ◽  
Sabrina Ferreira ◽  
Idelmo Rangel Garcia Júnior ◽  
...  

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