scholarly journals Proteomic response and molecular regulatory mechanisms of Bacillus cereus spores under ultrasound treatment

2021 ◽  
pp. 105732
Author(s):  
Ruiling Lv ◽  
Donghong Liu ◽  
Wenjun Wang ◽  
Enbo Xu ◽  
Tian Ding ◽  
...  
2015 ◽  
Vol 35 (5) ◽  
pp. 615-621 ◽  
Author(s):  
Lulu Li ◽  
Jin Tan ◽  
Yuyang Miao ◽  
Ping Lei ◽  
Qiang Zhang

2021 ◽  
Vol 12 ◽  
Author(s):  
Wenye Lin ◽  
Ying Wang ◽  
Yoan Coudert ◽  
Daniel Kierzkowski

Specialized photosynthetic organs have appeared several times independently during the evolution of land plants. Phyllids, the leaf-like organs of bryophytes such as mosses or leafy liverworts, display a simple morphology, with a small number of cells and cell types and lack typical vascular tissue which contrasts greatly with flowering plants. Despite this, the leaf structures of these two plant types share many morphological characteristics. In this review, we summarize the current understanding of leaf morphogenesis in the model moss Physcomitrium patens, focusing on the underlying cellular patterns and molecular regulatory mechanisms. We discuss this knowledge in an evolutionary context and identify parallels between moss and flowering plant leaf development. Finally, we propose potential research directions that may help to answer fundamental questions in plant development using moss leaves as a model system.


Author(s):  
Anton Sumarpo ◽  
Agnes Anania Triavika Sahamastuti ◽  
Gisella Edny Tjugianto ◽  
Kenny Yonathan ◽  
David Agustriawan

Objectives: Our present study was done to understand molecular regulatory mechanisms of IQGAP proteins and their potentials as biomarker in pancreatic cancer.Methods: In this review, relevant studies were obtained by assessing the PubMed database using the combination of words that included “IQGAP” and “pancreatic cancer”.Results: There is an increasing evidence showing that the expression of IQGAP1 and IQGAP3 is positively correlated with tumorigenesis; however, IQGAP2 might play a role to suppress tumor progression.Conclusion: IQGAP proteins might have potentials as predictive and prognostic biomarker for human pancreatic cancer.


2019 ◽  
Vol 64 (No. 11) ◽  
pp. 439-447
Author(s):  
Ji-Shun Tang ◽  
Wen-Ping Hu ◽  
Ran Di ◽  
Xiang-Yu Wang ◽  
Xiao-Sheng Zhang ◽  
...  

To elucidate how expression characteristics of BMPR1B, BMP15, and GDF9 are associated with sheep reproduction, tissue-specific mRNA expression of these genes in Small Tail Han (STH) ewes (a polytocous breed) and Sunite (SNT) ewes (a monotocous breed) in the follicular phase were investigated using transcription profiling and quantitative real-time PCR (qPCR). Expression levels of the three genes were all highest in ovaries of the two sheep breeds, and BMPR1B and GDF9 expression in the ovarian tissue was significantly higher in STH sheep compared with SNT sheep (P < 0.01), whereas BMP15 expression in pituitary, ovarian, oviduct, and uterine tissues was significantly lower in STH sheep compared with SNT sheep (P < 0.01). This study revealed that BMPR1B, BMP15, and GDF9 may play important roles in the hypothalamic-pituitary-gonadal axis, especially in the ovary, which may affect sheep prolificacy. BMPR1B and GDF9 expression might increase litter size, whereas BMP15 expression may decrease litter size. These results provide preliminary information regarding molecular regulatory mechanisms underlying sheep prolificacy.  


2016 ◽  
Vol 39 (10) ◽  
pp. 2260-2275 ◽  
Author(s):  
Ishmael Mutanda ◽  
Masashi Inafuku ◽  
Seikoh Saitoh ◽  
Hironori Iwasaki ◽  
Masakazu Fukuta ◽  
...  

Author(s):  
Xuhui Chen ◽  
Kai Liu ◽  
Wen Xu ◽  
Gang Zhou ◽  
Chengfu Yuan

Background: Long non-coding RNA rhabdomyosarcoma 2-associated transcript (LncRNA RMST) will affect every aspect of tumor progression, such as proliferation, translocation and apoptosis. As a result, RMST can be used as an attractive biomarker for early diagnosis and clinical therapies of different disease states. This article aims to review pathophysiological functions, molecular mechanisms as well as promising biotherapies of RMST in multiple tumors. Methods: Through the systematic induction and summary of 46 papers published in PubMed concerning this study, the molecular mechanisms of RMST in all kinds of tumors have been reviewed. Results: LncRNA RMST is a tumor-related regulatory mediator, aberrantly expressed in diverse tumors, regarding medullary thyroid cancer, hepatocellular carcinoma, endometrial carcinoma, colon cancer, pancreatic cancer, glioma, Wilm’s tumor and breast cancer. Furthermore, as a mechanism-based player, RMST probably guides the translation and post-translation modification, containing DNA methylation and SUMOylation. It is capable of regulating distinct tumor cells and stem cells of biological behaviors via various molecular pathways. Conclusion: LncRNA RMST, potentially as an original therapeutic target, is valuable in the occurrence, development and apoptosis of different tumors.


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