Prognostic significance of serum lactate dehydrogenase in patients undergoing radical cystectomy for bladder cancer

2020 ◽  
Vol 38 (11) ◽  
pp. 852.e1-852.e9
Author(s):  
Shiqiang Su ◽  
Lizhe Liu ◽  
Chao Sun ◽  
Lijun Yang ◽  
Yanhua Nie ◽  
...  
CHEST Journal ◽  
2004 ◽  
Vol 126 (4) ◽  
pp. 873S ◽  
Author(s):  
Joe G. Zein ◽  
Gregory L. Lee ◽  
Maroun Tawk ◽  
Mohammed Dabaja ◽  
Gary T. Kinasewitz

1996 ◽  
Vol 13 (1) ◽  
pp. 19-29 ◽  
Author(s):  
Samia A. Ahmed ◽  
Mohamed Z. Gad

Serum lactate dehydrogenase (LDH) isoenzyme and amino acid (a. a) patterns were evaluated in comparison to several other biochemical parameters for liver and renal function with the objective of clarifying the differential diagnosis of hepatic disorders and predicting the outcome of schistosomal infection in Egyptian patients. Patients examined included those with complicated hepatic disorders and others with different stages of schistosomal infestation, hepatoma or bladder cancer, in addition to a normal control group. Several biochemical parameters appeared to be useful in establishing consistent differences or similarities between the studied groups. Examples are; elevated serum AST/ AL T ratio and methionine content in chronic schistosomiasis, elevated serum urea/creatinine ratio and leucine content in all schistosomal patients and extremely high levels of N-acetyl-β-D-glucosaminidase (NAG) in the urine of non-schistosomal bladder cancer patients. In addition, characteristic LDH isoenzyme profiles distinguish between the studied groups, in particular separating chronic schistosomiasis from schistosomal bladder cancer and hepatoma from other hepatic disorders.


2021 ◽  
Vol 8 (14) ◽  
pp. 866-870
Author(s):  
Pradeep Narayanan ◽  
Narendran Ambedkar ◽  
Prakash Senthaizhselvan ◽  
Sabu Augustine

BACKGROUND Sepsis is a potentially life threatening medical emergency. It should be diagnosed at the earliest and treated effectively to prevent mortality. Therefore, there is a need for parameters which are simple, reliable and cost effective which help in predicting the prognosis and help in managing the patient with sepsis more efficaciously. METHODS A total of seventy patients, 42 male and 28 female patients, over a period of one year, who fulfilled the inclusion and exclusion criteria was included in the study. In this study various clinical variables and biochemical markers including serum lactate dehydrogenase (LDH) were compared among survivor and non–survivor groups and analysed. RESULTS In this study out of 70 patients, 36 patients [51.4 %] expired. Various clinical variables and biochemical markers including serum LDH [on day 1 & day 3], were compared among survivor and non–survivor groups and analysed. Pulse rate, mean arterial pressure (MAP), total leucocyte count, renal function test (RFT), liver function test (LFT), day 3 LDH levels and requirement of ventilator support showed statistically significant difference among the survivor and non-survivor groups. CONCLUSIONS Despite the recent medical advances, sepsis is a multiorgan disease with significant mortality. Hence, we need simple and effective parameters which are essential in assessing the prognosis and in guiding the treatment protocols. This study focused on simple clinical and biochemical parameters with special reference to LDH, which helped us in predicting the mortality. KEYWORDS Markers, Serum LDH, Sepsis, Survival


1994 ◽  
Vol 6 (3) ◽  
pp. 204-210 ◽  
Author(s):  
G. Bacci ◽  
S. Ferrari ◽  
L. Sangiorgi ◽  
P. Picci ◽  
R. Casadei ◽  
...  

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