Incidence rate of sudden death in epilepsy: A systematic review and meta-analysis

2018 ◽  
Vol 86 ◽  
pp. 193-199 ◽  
Author(s):  
Erik Saetre ◽  
Michael Abdelnoor
Keyword(s):  
Systematic Review ◽  
Sudden Death ◽  
Incidence Rate ◽  
Meta Analysis

scholarly journals Epidemiology of injuries in professional football: a systematic review and meta-analysis

2019 ◽  
Vol 54 (12) ◽  
pp. 711-718 ◽  
Author(s):  
Alejandro López-Valenciano ◽  
Iñaki Ruiz-Pérez ◽  
Alberto Garcia-Gómez ◽  
Francisco J Vera-Garcia ◽  
Mark De Ste Croix ◽  
...  
Keyword(s):  
Systematic Review ◽  
Incidence Rate ◽  
Meta Analysis ◽  
Epidemiological Data ◽  
Pooled Analysis ◽  
Incidence Rates ◽  
Football Players ◽  
Injury Incidence ◽  
Lower Extremity Injuries ◽  
Trial Quality

ObjectiveWe performed a systematic review and meta-analysis of epidemiological data of injuries in professional male football.MethodForty-four studies have reported the incidence of injuries in football. Two reviewers independently extracted data and assessed trial quality using the Strengthening the Reporting of Observational Studies in Epidemiology statement and Newcastle Ottawa Scale. Studies were combined in a pooled analysis using a Poisson random effects regression model.ResultsThe overall incidence of injuries in professional male football players was 8.1 injuries/1000 hours of exposure. Match injury incidence (36 injuries/1000 hours of exposure) was almost 10 times higher than training injury incidence rate (3.7 injuries/1000 hours of exposure). Lower extremity injuries had the highest incidence rates (6.8 injuries/1000 hours of exposure). The most common types of injuries were muscle/tendon (4.6 injuries/1000 hours of exposure), which were frequently associated with traumatic incidents. Minor injuries (1–3 days of time loss) were the most common. The incidence rate of injuries in the top 5 European professional leagues was not different to that of the professional leagues in other countries (6.8 vs 7.6 injuries/1000 hours of exposure, respectively).ConclusionsProfessional male football players have a substantial risk of sustaining injuries, especially during matches.

scholarly journals Incidence rate and clinical impacts of arrhythmia following COVID-19: a systematic review and meta-analysis of 17,435 patients

Critical Care ◽  
2020 ◽  
Vol 24 (1) ◽  
Author(s):  
Shu-Chen Liao ◽  
Shih-Chieh Shao ◽  
Chi-Wen Cheng ◽  
Yung-Chang Chen ◽  
Ming-Jui Hung
Keyword(s):  
Systematic Review ◽  
Incidence Rate ◽  
Meta Analysis

Metabolic complications with the use of mTOR inhibitors for cancer therapy: A systematic review and meta-analysis.

2013 ◽  
Vol 31 (6_suppl) ◽  
pp. 398-398 ◽  
Author(s):  
Shanthi Sivendran ◽  
Jian Ying ◽  
Benjamin Adam Gartrell ◽  
Neeraj Agarwal ◽  
Kenneth M. Boucher ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Adverse Events ◽  
Incidence Rate ◽  
Meta Analysis ◽  
Mtor Inhibitors ◽  
Incidence Rates ◽  
Metabolic Complications ◽  
Randomized Controlled Clinical Trials ◽  
Grade 3

398 Background: mTOR inhibitors are approved in several malignancies including renal cell carcinoma (RCC). The risk of metabolic complications with these agents is not well characterized. Methods: PubMed was searched for articles published from 2001 until 2011. Eligible studies included prospective randomized trials evaluating temsirolimus, everolimus, and ridaforolimus in patients with all solid tumor malignancies. 16 eligible phase II clinical trials and 8 randomized controlled clinical trials were included in a systematic review and meta-analysis and the number of metabolic related AEs including hyperglycemia, hypercholesterolemia, and hypertriglyceridemia were extracted. Incidence rates and incident rate ratios were calculated. Results: In total, 24 trials (including 4,261 patients) were included. The average incidence rate of any grade metabolic adverse events and grade 3-4 metabolic adverse events was 0.70 per patient and 0.11 (95% CI, 0.08, 0.15) per patient respectively. Analysis of the 3,317 patients across 8 RCT’s revealed that the log incidence rate ratio (IRR) of any grade metabolic adverse events with mTOR inhibitor therapy compared with control was 1.08 (95% CI, 0.84, 1.31) using a random-effects model. The risk of grade 3-4 adverse events was also increased with an IRR of 1.52 (95% CI, 1.05, 1.99). The IRR of all grade hyperglycemia was 1.08 (95% CI, 0.76, 1.40) and of grade 3-4 hyperglycemia was 1.66 (95% CI, 1.12, 2.20). The IRR of all grade hypertriglyceridemia was 0.91 (95% CI, 0.56, 1.26) and of grade 3-4 hypertriglyceridemia was 0.70 (95% CI,- 0.43, 1.83). The IRR of all grade hypercholesterolemia was 1.21 (95% CI, 0.77, 1.65) and of grade 3-4 hypercholesterolemia was 1.21 (95% CI, 0.77, 1.65). These findings suggest a statistically significant increase in the risk of hyperglycemia, hypercholesterolemia (all grades and grade 3 and 4), and all grade hypertriglyceridemia associated with mTOR therapy when compared with control. Conclusions: The risk of all grade and grade 3-4 metabolic adverse events are increased in patients treated with mTOR inhibitors compared with control. However, grade 3-4 metabolic adverse events remain relatively uncommon.

scholarly journals A systematic review and meta-analysis on incidence of prostate cancer in Iran

2019 ◽  
Vol 9 (2) ◽  
pp. 92-98 ◽  
Author(s):  
Asaad Moradi ◽  
Mohammad Zamani ◽  
Emadoddin Moudi
Keyword(s):  
Prostate Cancer ◽  
Systematic Review ◽  
Incidence Rate ◽  
Meta Analysis ◽  
Scientific Information ◽  
Epidemiological Studies ◽  
Health Concern ◽  
Cross Sectional ◽  
Cancer Occurrence ◽  
Iranian Populations

Background: Prostate cancer is a global health concern. In Iran, its epidemiology is not precisely recognized. We aimed to evaluate incidence of prostate cancer among Iranian populations. Methods: In this systematic review, we searched the databases PubMed, Web of Sciences, Scopus and Google Scholar for English studies and the databases Magiran, Scientific information Database, IranMedex and IranDoc for Persian studies, using related keywords. The cross sectional articles published from inception to 31 December 2018 were included. Meta-analysis was conducted on the collected data with STATA software using random effects model. Results: Out of 763 articles initially obtained, 9 articles were finally included after applying the predefined exclusion criteria. Analysis of 9 studies on the incidence of prostate cancer showed a crude rate of 7.1 per 100000 population (95% confidence interval [CI]: 5.6-8.6). Also, the pooled age-standardized incidence rate was 8.7 per 100000 (95% CI: 6.7-10.4). Studies performed in the period 2004-2012 had significantly a higher pooled estimate of the crude incidence rate (9.2 per 100000 [95% CI: 7.9-10.4]) compared with those conducted in the period 1996-2003 (4.5 per 100000 [95% CI: 2.8-6.2]). This trend was also observed based on the age-standardized incidence rate (11 per 100000 [95% CI: 9.4-12.5] versus 6.3 per 100000[95% CI: 4-8.5]).Conclusion: Despite low rate of prostate cancer occurrence in Iran, it is recommended that preventive measures be taken against this disease by health policymakers. Also, more epidemiological studies are needed to better find out the pattern of prostate cancer among Iranian populations.

scholarly journals The International Incidence of Traumatic Brain Injury: A Systematic Review and Meta-Analysis

2016 ◽  
Vol 43 (6) ◽  
pp. 774-785 ◽  
Author(s):  
Rita Nguyen ◽  
Kirsten M. Fiest ◽  
Jane McChesney ◽  
Churl-Su Kwon ◽  
Nathalie Jette ◽  
...  
Keyword(s):  
Systematic Review ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Confidence Interval ◽  
Incidence Rate ◽  
Meta Analysis ◽  
Demographic Data ◽  
Original Research ◽  
Incidence Proportion ◽  
Global Epidemiology

AbstractBackground: Understanding the epidemiology of traumatic brain injury (TBI) is essential to shape public health policy, implement prevention strategies, and justify allocation of resources toward research, education, and rehabilitation in TBI. There is not, to our knowledge, a systematic review of population-based studies addressing the epidemiology of TBI that includes all subtypes. We performed a comprehensive systematic review and meta-analysis of the worldwide incidence of TBI. Methods: A search was conducted on May 23, 2014, in Medline and EMBASE according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Abstracts were screened independently and in duplicate to identify original research. Study quality and ascertainment bias were assessed in duplicate using a previously published tool. Demographic data and incidence estimates from each study were recorded, along with stratification by age, gender, year of data collection, and severity. Results: The search strategy yielded 4944 citations. Two hundred and sixteen articles met criteria for full-text review; 144 were excluded. Hand searching resulted in ten additional articles. Eighty-two studies met all eligibility criteria. The pooled annual incidence proportion for all ages was 295 per 100,000 (95% confidence interval: 274-317). The pooled incidence rate for all ages was 349 (95% confidence interval: 96.2-1266) per 100,000 person-years. Incidence proportion and incidence rate were examined to see if associated with age, sex, country, or severity. Conclusions: We conclude that most TBIs are mild and most TBIs occur in males among the adult population. The incidence of TBI varies widely by ages and between countries. Despite being an important medical, economic, and social problem, the global epidemiology of TBI is still not well-characterized in the current literature. Understanding the incidence of TBI, particularly mild TBI, remains challenging because of nonstandardized reporting among neuroepidemiological studies.

scholarly journals Oral Complications of Chemotherapy on Paediatric Patients with Cancer: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 5 (1) ◽  
pp. 25
Author(s):  
Ana Sofia Alves ◽  
Gunel Kizi ◽  
Ana Raquel Barata ◽  
Paulo Mascarenhas ◽  
Irene Ventura
Keyword(s):  
Systematic Review ◽  
Incidence Rate ◽  
Web Of Science ◽  
Meta Analysis ◽  
Paediatric Oncology ◽  
Cochrane Library ◽  
Patients With Cancer ◽  
Search Results ◽  
Oral Complications ◽  
Paediatric Patients

The goal of cancer treatment is to fight and/or control cancer. The aim of this study was to review and meta-analyse the incidence of main oral complications in paediatric oncology during chemotherapy. The search results were obtained from B-on, Web of Science, Scopus, Cochrane Library and PubMed databases. Of 1032 articles potentially relevant, 13 were included in this review. The overall incidence of caries, gingivitis, ulcers, mucositis, and candidiasis was 67.8%, 55.6%, 44.2%, 41.6%, and, 29.5%, respectively. During chemotherapy, paediatric patients with cancer present higher incidence of caries and gingivitis. Incidence rate meta-analysis show high heterogeneity. More studies should be done to reduce uncertainty.

Incidence Rate of COVID-19 Infection in Hemoglobinopathies: A Systematic Review and Meta-analysis

Hemoglobin ◽  
2021 ◽  
pp. 1-9
Author(s):  
Sezaneh Haghpanah ◽  
Mahnaz Hosseini-Bensenjan ◽  
Mehrab Sayadi ◽  
Mehran Karimi
Keyword(s):  
Systematic Review ◽  
Incidence Rate ◽  
Meta Analysis

scholarly journals Does Intraperitoneal Chemotherapy Increase the Incidence of Anastomotic Leakage after Colorectal Cancer Surgery: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Yu Yang ◽  
Yuxuan Li ◽  
Xiaohui Du
Keyword(s):  
Colorectal Cancer ◽  
Systematic Review ◽  
Anastomotic Leakage ◽  
Incidence Rate ◽  
Intraperitoneal Chemotherapy ◽  
Meta Analysis ◽  
Abdominal Cavity ◽  
Cancer Surgery ◽  
Colorectal Cancer Surgery ◽  
Increased Risk

Purpose. To identify and evaluate the influence of intraperitoneal chemotherapy without hyperthermia (ICwh) to the incidence of anastomotic leakage (AL) after colorectal cancer surgery. Methods. A systematic review and meta-analysis were performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses in order to review all studies investigating the relationship between ICwh and AL in patients undergoing colorectal surgery. The primary outcome was overall incidence rate of anastomotic leakage. Results. Four studies were included in the final review. ICwh was associated with an overall increased risk of anastomotic leakage [OR 2.05 (1.06, 3.98), P = 0.03 ]. But there was no significant increased incidence rate when fluorouracil was implanted into the abdominal cavity for ICwh [OR 2.48 (0.55, 11.10), P = 0.24 ]. Conclusions. This meta-analysis provides some evidence to suggest ICwh may increase the incidence of postoperative AL in colorectal cancer. However, fluorouracil implantation for ICwh does not increase the risk of AL, which seems to be a relatively safe method of ICwh.

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