Incident epilepsy in the cognitively normal geriatric population, irrespective of seizure control, impairs quality of life

OBJECTIVE: understand the psychological considerations of the relationship between the effect of seizures upon the patients' perception of seizure control, depression, anxiety and quality of life (QoL). METHODS: 151 adult patients with epilepsy diagnosed for over two years were interviewed and responded the 31-Item Quality of Life in Epilepsy (QOLIE-31), the Trait Form of the State/Trait Anxiety Inventory (STAI II) and the Beck Depression Inventory (BDI). RESULTS: 45 patients were depressed (29.8%) and 29 (19.2%) had anxiety. Depression scores ranged from 0 to 49 (M=7.4; SD=8.9) and anxiety scores ranged from 19 to 69 (M=41.5, SD=11.9). Total QoL score was correlated to seizure control (p<0.001), perception of epilepsy control (p<0.001), anxiety (p<0.001), and depression (p=0.003). The perception of epilepsy control was correlated to seizure control (p<0.001), seizure frequency (p=0.001), anxiety (p<0.001) and depression (p<0.001). Seizure control was associated to anxiety (p=0.033) and depression (p<0.001). There was co-morbidity between anxiety and depression (p<0.001). CONCLUSION: This study highlights the importance of the seizure frequency and control to the evaluation of perception of epilepsy control and shows that anxiety and depression in epilepsy are predicted by seizure-related (seizure frequency and control) and psychosocial aspects (perception of control and QoL) together.

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Evaluation of the Effects of Clobazam on Seizure Control and Quality of Life in Children With Lennox-Gastaut Syndrome: A Pilot Study

Journal of Child Neurology ◽

10.1177/0883073819836534 ◽

2019 ◽

Vol 34 (8) ◽

pp. 432-439 ◽

Cited By ~ 1

Author(s):

Arie Weinstock ◽

Nitin Agarwal ◽

Osman Farooq ◽

Zaheer Cheema ◽

Deanna Hamilton ◽

...

Keyword(s):

Quality Of Life ◽

Pilot Study ◽

Seizure Control

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Quality of Life Measurements in Epilepsy

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques ◽

10.1017/s0317167100020898 ◽

1996 ◽

Vol 23 (S2) ◽

pp. S3-S5 ◽

Cited By ~ 2

Author(s):

David Chadwick

Keyword(s):

Quality Of Life ◽

Health Status ◽

Social Functioning ◽

Seizure Control ◽

Well Being ◽

General Health Status ◽

Life Issues ◽

Disease Specific ◽

Quality Of Life Measurements

ABSTRACT:In the treatment of the patient with epilepsy not only seizure control but quality of life issues are important aspects of management. Aspects that have an impact on the quality of life include seizure frequency and severity, social functioning, psychological well-being, disease specific measures, and general health status.

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Surgery for low-grade glioma infiltrating the central cerebral region: location as a predictive factor for neurological deficit, epileptological outcome, and quality of life

Journal of Neurosurgery ◽

10.3171/2013.5.jns122235 ◽

2013 ◽

Vol 119 (2) ◽

pp. 318-323 ◽

Cited By ~ 37

Author(s):

Philippe Schucht ◽

Fadi Ghareeb ◽

Hugues Duffau

Keyword(s):

Quality Of Life ◽

Return To Work ◽

Seizure Control ◽

Extent Of Resection ◽

Low Grade Glioma ◽

Neurological Deficits ◽

Main Concern ◽

Low Grade ◽

Who Grade

Object A main concern with regard to surgery for low-grade glioma (LGG, WHO Grade II) is maintenance of the patient's functional integrity. This concern is particularly relevant for gliomas in the central region, where damage can have grave repercussions. The authors evaluated postsurgical outcomes with regard to neurological deficits, seizures, and quality of life. Methods Outcomes were compared for 33 patients with central LGG (central cohort) and a control cohort of 31 patients with frontal LGG (frontal cohort), all of whom had had medically intractable seizures before undergoing surgery with mapping while awake. All surgeries were performed in the period from February 2007 through April 2010 at the same institution. Results For the central cohort, the median extent of resection was 92% (range 80%–97%), and for the frontal cohort, the median extent of resection was 93% (range 83%–98%; p = 1.0). Although the rate of mild neurological deficits was similar for both groups, seizure freedom (Engel Class I) was achieved for only 4 (12.1%) of 33 patients in the central cohort compared with 26 (83.9%) of 31 patients in the frontal cohort (p < 0.0001). The rate of return to work was lower for patients in the central cohort (4 [12.1%] of 33) than for the patients in the frontal cohort (28 [90.3%] of 31; p < 0.0001). Conclusions Resection of central LGG is feasible and safe when appropriate intraoperative mapping is used. However, seizure control for these patients remains poor, a finding that contrasts markedly with seizure control for patients in the frontal cohort and with that reported in the literature. For patients with central LGG, poor seizure control ultimately determines quality of life because most will not be able to return to work.

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Cognitive behaviour therapy for epilepsy: improving seizure control and quality of life

http://isrctn.org/> ◽

10.1186/isrctn31786019 ◽

2013 ◽

Author(s):

Laura H Goldstein

Keyword(s):

Quality Of Life ◽

Cognitive Behaviour Therapy ◽

Seizure Control ◽

Behaviour Therapy ◽

Cognitive Behaviour

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Palliative hemispherotomy in children with bilateral seizure onset

Journal of Neurosurgery Pediatrics ◽

10.3171/2011.12.peds11334 ◽

2012 ◽

Vol 9 (4) ◽

pp. 381-388 ◽

Cited By ~ 18

Author(s):

Michael Anthony Ciliberto ◽

David Limbrick ◽

Alexander Powers ◽

Jeffrey B. Titus ◽

Rebecca Munro ◽

...

Keyword(s):

Quality Of Life ◽

Mr Imaging ◽

Seizure Control ◽

Epileptiform Activity ◽

Intractable Epilepsy ◽

Retrospective Chart Review ◽

Seizure Onset ◽

Significant Burden

Object Intractable epilepsy is a significant burden on families and on the cognitive development and quality of life (QOL) of patients. Periinsular hemispherotomy (PIH) for medically intractable epilepsy can benefit patients who qualify for this procedure. The ideal hemispherotomy candidate has ipsilateral ictal and interictal epileptiform activity, unilateral MR imaging abnormalities, contralateral hemiplegia, and a normal contralateral hemisphere. However, certain patients present with a mixed picture of bilateral electroencephalography (EEG) findings and severe intractable epilepsy, prompting consideration of a more aggressive treatment approach. This report introduces the possibility of surgery for patients who normally would not meet criteria for this treatment modality. Methods In this retrospective chart review, the authors report on 7 patients with bilateral seizure onset noted on routine or video-EEG monitoring. A QOL phone questionnaire, based on the Quality of Life in Childhood Epilepsy tool, was administered to a parent. The authors reviewed each patient's chart for surgical complications, changes in examination, QOL, limited neuropsychological outcomes, and seizure outcomes. They also investigated each chart for MR imaging and EEG findings as well as the patient's epilepsy clinic notes for seizure semiology and frequency. Results All patients enjoyed a decrease in seizure frequency and a subjective increase in QOL after PIH. Five patients (71%) achieved Engel Class I or II seizure control. The mean follow-up was 3.64 years (2–5.3 years). One patient is now off all antiseizure medication. No patient had a decrement in Full Scale IQ on postsurgical testing, and 2 (28.5%) of 7 individuals had increased adaptive and social functioning. Postsurgical examination changes included hemiplegia and homonymous hemianopia. Conclusions Hemispherotomy in patients with intractable epilepsy is generally reserved for individuals with unilateral epileptiform abnormalities or lesions on MR imaging. Seven patients in this study benefited from surgery despite bilateral seizure onset with improvement in seizure control and overall QOL. Thus, bilateral ictal onset does not necessarily preclude consideration for hemispherotomy in selected patients with severe medically refractory epilepsy.

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Understanding the Psychological Issues in The Geriatric Population in The Times of COVID-19- A Critical Review from The Lens of a Psychologist

10.31219/osf.io/na6z9 ◽

2021 ◽

Author(s):

Mansi Sharma

Keyword(s):

Quality Of Life ◽

Critical Review ◽

The Elderly ◽

Geriatric Population ◽

Psychological Issues ◽

Mutant Variant ◽

Study Analyse ◽

The Times ◽

And Coping

The first wave of the Covid-19 pandemic hit India in January 2020 when the first confirmed case was reported at a general hospital of Kerala. Since then, the number of reported cases kept on increasing at a steady pace, we saw deaths, rise, fall and stagnancy in the number of cases in India while the figures of deaths reported remained worrisome. While India is currently battling with the deadly double mutant variant of the virus, the present critical review is an attempt to study, analyse and understand the need of catering to the needs of geriatric population, especially in a collectivistic culture like India, where elderly issues, psychological difficulties, and coping mechanism takes a back seat while there is constant fear of leading a healthy life especially in the testing times of a national pandemic, COVID-19. This critical review is an attempt to highlight the various issues dealt by the average Indian elderly, their lifestyle after retirement, sustaining means of livelihood in times of uncertainty and keeping a positive mindset for a better quality of life. This paper also attempts to enumerate few strategies required to inculcate a sense of life satisfaction and improved quality of life among the elderly.

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MUSTARD OIL – GARLIC COMBO MASSAGE- AN EFFECTIVE KNEE PAIN HOME REMEDY

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v5i9.2170 ◽

2021 ◽

Vol 5 (9) ◽

Author(s):

Manpreet Sharma ◽

Mandeep Kaur ◽

Hardeep Kaur

Keyword(s):

Quality Of Life ◽

Pain Score ◽

Knee Pain ◽

Conventional Group ◽

Mustard Oil ◽

Geriatric Population ◽

Home Remedy ◽

Group I ◽

Experimental Group

Background: Knee pain is one of the most prevalent disorders affecting the quality of life of elderly age group and geriatric population. This can occur due to numerous reasons including obesity, constant weight bearing rheumatic diseases, rheumatoid arthritis, reactive arthritis as well as osteoarthritis that may lead to swelling, redness, warmth, weakness, tenderness, and stiffness of the joint. A number of pain reliever formulations are available in the market that include NSAIDs based creams, intra synovial injections and steroid based formulations however none of them proves to be completely effective in improving the quality of life of geriatric population. In addition to it, there are a number of reported side effects/adverse events related to these formulations. Methods: The present study was conducted to evaluate the effectiveness of a home remedy prepared from Mustard oil and garlic as mentioned in ancient texts of Ayurveda in the knee pain subjects for improving quality of life. A quasi-experimental study (two group pretest and posttest design) was conducted in 70 subjects in two groups of 35 each with knee joint pain meeting the inclusion and exclusion criteria. Pain was assessed using numeric pain scale. Data analysis was done using inferential and descriptive statistics. Majority of the samples in both group I and group II had moderate and severe level of pain. Results: After intervention, the pain level had reduced to mild level in experimental group as compared to conventional group. The mean pretest values of pain score in experimental group had significant difference during posttest measurement of mean pain score. The difference was found to be significant in experimental group with warm mustard oil massage, but in conventional group difference was not significant. Conclusion: Mustard oil-garlic combo massage proved to be a good home remedy in knee pain Key words: effectiveness, mustard oil with garlic massage, knee pain

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