Photodynamic Therapy Synergize with PD-L1 Checkpoint Blockade for Immunotherapy of Colorectal Cancer by Multifunctional Nanoparticle

2021 ◽  
Author(s):  
Zeting Yuan ◽  
Guohua Fan ◽  
Honglei Wu ◽  
Chaolian Liu ◽  
Yueping Zhan ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Photodynamic Therapy ◽  
Checkpoint Blockade ◽  
Multifunctional Nanoparticle

scholarly journals Photodynamic Therapy for Advanced Rectal Cancer: A Case Report

2020 ◽  
Vol 4 (6) ◽  
Author(s):  
Lemei Chen ◽  
Yanping Liu ◽  
Ping Xie ◽  
Huizhen Fan
Keyword(s):  
Colorectal Cancer ◽  
Rectal Cancer ◽  
Photodynamic Therapy ◽  
Palliative Treatment ◽  
Treatment Process ◽  
Advanced Colorectal Cancer ◽  
Advanced Rectal Cancer ◽  
Tumor Treatment ◽  
Potential Value ◽  
Case Data

Objective: To investigate the potential value of PDT(photodynamic therapy) in the treatment of rectal cancer by reviewing the diagnosis and treatment process of a patient with advanced rectal cancer who lost the opportunity of surgery. Methods: Select the case data of a patient receiving photodynamic therapy in our hospital, and analyze the photodynamic mechanism, safety and efficiency, and discuss the efficacy of photodynamic therapy. Results: After the patient received photodynamic therapy, re-examination of the endoscopy showed that the intestinal cavity was smoother than before, the bowel was difficult, and the symptoms of blood in the stool improved. Conclusion: Photodynamic therapy can be used as a radical or palliative treatment for clinical tumor treatment. Because of its advantages of minimally invasive, tissue-specific, repetitive and synergistic radiotherapy and chemotherapy, it plays an important role in early or middle-advanced colorectal cancer and is worthy of clinical promotion.

Immunological Aspects of Photodynamic Therapy of Liver Tumors in a Rat Model for Colorectal Cancer ¶

2007 ◽  
Vol 78 (3) ◽  
pp. 235-240
Author(s):  
Frederieke H. Van Duijnhoven ◽  
Remco I. J. M. Aalbers ◽  
Jeroen P. Rovers ◽  
Onno T. Terpstra ◽  
Peter J. K. Kuppen
Keyword(s):  
Colorectal Cancer ◽  
Photodynamic Therapy ◽  
Rat Model ◽  
Liver Tumors
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