Factors Associated With Hepatic Steatosis in Obese Children and Adolescents

DOI: http://dx.doi.org/10.5007/1980-0037.2017v19n4p459 Physical exercise is one of the forms of prevention and treatment of obesity and associated diseases such as hepatic steatosis. The aim of this study was to analyze whether hepatic steatosis interferes in the effect of physical exercise on the body composition of obese children and adolescents. The sample consists of 40 obese individuals, 13 children (8.17±1.33 years) and 27 adolescents (12.28±1.36 years). Total and segmental body composition was estimated by DEXA. Anthropometric measurements were performed, as well as ultrasound examination of the liver to measure intra-abdominal and subcutaneous fat, and to diagnose hepatic steatosis (HS). The intervention consisted of 20 weeks, with recreational/competitive activities being applied to children and, for adolescents, concurrent training (aerobic and resistance). The Levene’s, repeated-measures ANOVA and effect size tests (ES) by Eta-Squared were performed. It was observed that, although not statistically significant, analyzing the effect size, physical activity in both children (body fat ES effect time= 0.210 and ES effect group= 0.208; fat mass ES effect group = 0.338; fat android ES effect Interaction= 0.267), and adolescents (intra-abdominal fat ES effect group = 0.230) regardless of whether or not HS was effective in reducing body fat. Therefore, exercise was effective in improving the body composition of obese children and adolescents, regardless of HS.

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Hepatic steatosis in obese children and adolescents

Jornal de Pediatria ◽

10.2223/jped.2065 ◽

2011 ◽

Vol 87 (2) ◽

pp. 150-156 ◽

Cited By ~ 5

Author(s):

Maria Amélia S. M. Duarte ◽

Giselia Alves Pontes da Silva

Keyword(s):

Children And Adolescents ◽

Hepatic Steatosis ◽

Obese Children

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Feasibility of balanced steady-state free precession sequence at 1.5T for the evaluation of hepatic steatosis in obese children and adolescents

European Radiology ◽

10.1007/s00330-018-5344-z ◽

2018 ◽

Vol 28 (11) ◽

pp. 4479-4487 ◽

Cited By ~ 2

Author(s):

Hong-xi Zhang ◽

Jun-fen Fu ◽

Can Lai ◽

Feng-yu Tian ◽

Xiao-li Su ◽

...

Keyword(s):

Steady State ◽

Children And Adolescents ◽

Hepatic Steatosis ◽

Steady State Free Precession ◽

Free Precession ◽

Obese Children

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Hepatic Steatosis among Obese Children and Adolescents

Journal of Bangladesh College of Physicians and Surgeons ◽

10.3329/jbcps.v34i2.32290 ◽

2017 ◽

Vol 34 (2) ◽

pp. 57-63 ◽

Cited By ~ 1

Author(s):

Rumana Shelim ◽

Fauzia Mohsin ◽

Tahmina Begum ◽

MA Baki ◽

Sharmin Mahbuba ◽

...

Keyword(s):

Liver Disease ◽

Fatty Liver ◽

Lipid Profile ◽

Children And Adolescents ◽

Hepatic Steatosis ◽

Obese Children ◽

High Cholesterol ◽

Alcoholic Fatty Liver ◽

Increased Risk ◽

Metabolic Complication

Background: Chronic liver disease, known as non- alcoholic fatty liver disease (NAFLD) is a metabolic complication of obesity. Hepatic steatosis is an entity in the spectrum of NAFLD, ranges from simple steatosis to advanced fibrosis and cirrhosis.Objective: To identify prevalence of hepatic steatosis and to assess correlation between hepatic steatosis and anthropometry, SGPT and metabolic abnormalities of obese children and adolescents.Methodology: This cross sectional study included 50 obese children and adolescents, attending the Endocrine OPD of Dept. of Paediatrics in BIRDEM from June 2009 to December 2009. BMI e 95th centile for age and sex was used as an anthropometric marker to diagnose obesity. Obesity with any dismorphism, endocrine or chromosomal abnormalities were excluded. Fasting blood samples were collected for measurement of SGPT, blood glucose, lipid profile, FT4 &TSH. Sonographic findings of fatty liver include increased echogenicity of liver, blurring of vascular margins and increased acoustic attenuation.Results: Mean age of the children was 11.24 (8-18) years. High SGPT level was prevalent among 36% of obese children. The most prevalent abnormal lipid profile was high TG (78%) followed by high cholesterol level (68%). The prevalence of hepatic steatosis was 36% with male predominance (M 72.2%, F 27.8%). Mild hepatic steatosis was 72% followed by moderate 28%. High SGPT, high cholesterol and LDL were more prevalent in children with hepatic steatosis in comparison to children without steatosis (P <0.004, <0.05 and <0.04 respectively).Conclusion: Hyperlipidemia with raised SGPT are important signs of liver dysfunction in obese children with hepatic steatosis. Prevention of obesity and identification of children with an increased risk of NAFLD are important steps in preventing irreversible liver damage.J Bangladesh Coll Phys Surg 2016; 34(2): 57-63

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