Comparison of inflammatory markers in patients with diabetes mellitus versus those without before and after coronary arterial stenting

2003 ◽  
Vol 92 (8) ◽  
pp. 924-929 ◽  
Author(s):  
Atul Aggarwal ◽  
David J Schneider ◽  
Burton E Sobel ◽  
Harold L Dauerman
2019 ◽  
Vol 9 (9) ◽  
pp. 98 ◽  
Author(s):  
Kisokanth G. ◽  
Indrakumar J. ◽  
Prathapan S. ◽  
Joseph J. ◽  
Ilankoon I.M.P.S.

This study was aimed to assess the effectiveness of diabetes self-management education (DSME) in the improvement of glycemic control among patients with type 2 Diabetes Mellitus (T2DM) in Batticaloa District, Sri Lanka. The study was a prospective interventional study and conducted as a preliminary study at medical clinic, Base hospital, Kaluwanchikudy, Batticaloa. Thirty patients with T2DM were included based on inclusion and exclusion criteria. A structured individual diabetes self-management education for 10 hours (one hour per week) was delivered to diabetic patients by the trained Nurse Health Educator. Glycosylate hemoglobin (HbA1c) was assessed as a main outcome measure and Fasting Blood Sugar (FBS), Body Mass Index (BMI) of each patient were also measured and recorded before and after the intervention. The respondent rate was 96.7% (n = 29). Majority of them were females (n = 25, 86.2%). A Wilcoxon signed rank test showed that DSME had a statistically significant reduction in HbA1c [8.60 (IQR 2.60) vs. 7.40 (IQR 2.10), p = .000] and FBS level [159.00 (IQR 77.50) vs. 134.00 (IQR 40.50), p = .002] at 3 months of intervention. The mean BMI at baseline was higher compared to 3 months of intervention [24.88 (SD ± 3.06) vs. 24.19 (SD ± 2.79)] which was statistically significant (p = .000). Majority of participants (n = 22, 75.9%) had improved their HbA1c level by ≥ 0.5% in 3 months. The diabetes self-management education is an effective measure in improving glycemic control and other clinical parameters among patients with T2DM. Thus, DSME needs to be implemented among clinic patients with T2DM for the better outcome and the preventions of complications.


2017 ◽  
Vol 2 (1) ◽  
pp. 8
Author(s):  
Siswanto Siswanto ◽  
Ismail Kamba ◽  
Siti Aminah

Diabetes mellitus is one of the communicable diseases that have become a public health problem, not only in Indonesia but also the world. Currently morbidity of diabetes mellitus is increasing every year, where in 2006 there were 14 million people in 2011 and ranks fourth with 773 cases. DM is also a cause of disease mortality by 5.8%. And Samarinda own particular Islamic Hospital years 2009, there were 449 patients with DM, and 2011 an increase in the 1931 patients with diabetes mellitus. To increase patients’ knowledge about diabetes and diabetic patients be directing attitudes that support or positive attitude towards keeping blood glucose levels to remain normal. Methode to use pra eksperiment with one group pretest posttest. individual conseling withAudiovisual media. There is increased knowledge about diabetes diabetic patients before and after intervention with increasing value of 3.77 (p value = 0.000) and increase in attitudes regarding diabetes mellitus diabetic patients with an increase in the value of 5,35 (p value = 0.003). There was an increase in knowledge and attitudes of patients hospitalized with diabetes mellitus hospital after islam samarinda given nutritional counseling using audio-visual media


2016 ◽  
Vol 55 (3) ◽  
pp. 179-184 ◽  
Author(s):  
Davorina Petek ◽  
Mitja Mlakar

Abstract Background A new organisation at the primary level, called model practices, introduces a 0.5 full-time equivalent nurse practitioner as a regular member of the team. Nurse practitioners are in charge of registers of chronic patients, and implement an active approach into medical care. Selected quality indicators define the quality of management. The majority of studies confirm the effectiveness of the extended team in the quality of care, which is similar or improved when compared to care performed by the physician alone. The aim of the study is to compare the quality of management of patients with diabetes mellitus type 2 before and after the introduction of model practices. Methods A cohort retrospective study was based on medical records from three practices. Process quality indicators, such as regularity of HbA1c measurement, blood pressure measurement, foot exam, referral to eye exam, performance of yearly laboratory tests and HbA1c level before and after the introduction of model practices were compared. Results The final sample consisted of 132 patients, whose diabetes care was exclusively performed at the primary care level. The process of care has significantly improved after the delivery of model practices. The most outstanding is the increase of foot exam and HbA1c testing. We could not prove better glycaemic control (p>0.1). Nevertheless, the proposed benchmark for the suggested quality process and outcome indicators were mostly exceeded in this cohort. Conclusion The introduction of a nurse into the team improves the process quality of care. Benchmarks for quality indicators are obtainable. Better outcomes of care need further confirmation.


2018 ◽  
Vol 50 (3) ◽  
pp. 788-791
Author(s):  
A. Moura Neto ◽  
T.G. Bovi ◽  
C.M. Righetto ◽  
A.R. Fiore ◽  
L.T. Lot ◽  
...  

Medicina ◽  
2020 ◽  
Vol 56 (12) ◽  
pp. 658
Author(s):  
Ieva Jurgeleviciene ◽  
Daiva Stanislovaitiene ◽  
Vacis Tatarunas ◽  
Marius Jurgelevicius ◽  
Dalia Zaliuniene

Background and objectives: Glycation occurs in a variety of human tissues and organs. Knowledge about the relationship between predictive biochemical factors such as absorption of glycated nail proteins and severity of type 2 diabetes mellitus (DM) and diabetic retinopathy (DR) remains limited. Materials and Methods: The study group consisted of patients with type 2 DM and DR (n = 32) and a control group (n = 28). Each patient underwent a comprehensive ophthalmic examination. The glycation process in nail clippings was evaluated in stages of in vitro glycation and deglycation stages. ATR–FTIR spectroscopy was used to calculate the infrared absorption in the region of interest. The absorption of solutions with nail clippings was evaluated by NanoDrop spectrophotometry. Absorption spectra differences before and after the exposure to fructosamine 3-kinase were compared between DM patients with DR and the control group. Results: The absorption of glycated nail protein greater than 83.00% increased the chance of developing DM and DR (OR = 15.909, 95% CI 3.914–64.660, p < 0.001). Absorption of glycated nail protein by ATR–FTIR spectroscopy in patients with DM and DR in vitro glycation was statistically significantly higher than in the control group; also absorption of solution with nails by NanoDrop spectroscopy was statistically significantly higher than in controls in vitro glycation and in vitro deglycation. After exposure to fructosamine 3-kinase, absorption of nail protein in DM + severe/proliferative DR group was statistically significantly lower in comparison with DM + mild/moderate group DR. Conclusions: Evaluation of glycated nail protein could be applied to evaluate the risk of having DM and for long-term observation of DM control.


2020 ◽  
Vol 37 (3) ◽  
pp. 33-39
Author(s):  
V. N. Barykov ◽  
A. G. Istomin ◽  
N. V. Markina ◽  
V. L. Tyulganova

Objective. To study the state of carbohydrate metabolism in patients after distal pancreatic resection and its effect on the development of postoperative complications. Materials and methods. Over 10 years, 47 patients have been operated on with various tumors of the body/tail of the pancreas and complications of chronic pancreatitis. In 16 of them, concomitant diabetes mellitus was diagnosed before surgery, and in 31 patients, carbohydrate metabolism was normal. Results. After surgery, from a group of patients with unchanged carbohydrate metabolism, 8 (25.8 %) developed diabetes mellitus. The following postoperative complications pancreatic fistula, inflammatory infiltrates and "fluid leakages in the abdominal cavity occurred in 68 % of cases. Out of 24 patients with diabetes mellitus, complications were registered in 21 (87.5 %) and of 23 diabetes-free patients in 11 (47.8 %). Conclusions. The total risk for the development of the postoperative abdominal complications after the distal resection in patients with diabetes mellitus, diagnosed before and after the intervention, is 7.6 times higher than in patients without diabetes.


1985 ◽  
Vol 53 (01) ◽  
pp. 118-121 ◽  
Author(s):  
J H v d Knaap ◽  
A C de Boer ◽  
M A G Pannebakker ◽  
W van Heerde ◽  
G J H den Ottolander

SummaryIn this longitudinal study we measured β-TG, PF4, fibrinolytic activity (extrinsic and euglobulin fraction), fibrinogen, FVIII RAg and FVIII Rcof before and after i.v. DDAVP (FPA was only measured before DDAVP) in 20 patients with diabetes mellitus. These parameters were measured on three occasions: phase I: during disregulation, phase II: after three weeks of strict control, phase III: after nine weeks of good control. Twenty-two healthy volunteers served as normal controls.No significant differences related to metabolic control were found for β-TG, PF4, FPA and fibrinogen. There was no change after i.v. DDAVP administration. Fibrinolytic activity showed a significant increase after i.v. DDAVP. Baseline values and post-DDAVP increase were not significantly different from our normal controls.FVIII RAg and FVIII Rcof were both significantly elevated in diabetes mellitus. Both increased significantly after DDAVP. The FVIII RAg release (ΔFVIII RAg) was significantly less in the diabetics. Fibrinolytic activity, FVIII RAg and FVIII Rcof are independent of the degree of metabolic control in patients with diabetes.


2017 ◽  
pp. 46-53
Author(s):  
A.Yu. Gurzhenko ◽  

The aim of the study: was to study the state of urate oxalate metabolism in patients with ureterolithiasis and concomitant diabetes mellitus, who underwent various methods of minimally invasive surgical treatment of urinary stones. Materials and methods. The study involved 204 people, of which men were 130 (63.7%), women – 74 (36.3%), the average age was 34.6±5.5 years. The study groups were divided into VI clinical groups: I – individuals with diabetes and ureterolithiasis, who underwent TUCL and cytrate per os (n=57); II – persons with DM and ureterolithiasis, who were TUCL (n=44); III – persons with DM and , who were administered by the ESWL (n=32); IV – persons with ureterolithiasis without DM, who underwent TUCL (n=41); V (control 1) – of the person with diabetes, who had an independent passage of stones from the ureter (n=18); VI (control 2) – healthy volunteers, with no signs of pathology (n=12). The diagnosis of the ureterolithiasis was verified using clinico-anamnestic, laboratory and instrumental research methods according to the methabolic homeostasis protocols, before and after the disintegration of the stones by the method of transurethral contact lithotripsy (TUСL) and ESWL. Results. Analysis of the above data showed that, in the presence of ureterolithiasis, there were significant changes in diurnal pH values in the form of monotony of the curve of indicators, with a significantly high shift towards acidification. Persistently acidic urine reflects the peculiarities of the urate urolythiasis in conditions of NAM, indicates the absence of an isolated violation by acute calculous obstruction and defines this state as a bilateral process. Hypocytraturia was established in all cases of ureterolithiasis, but in the urine of people with diabetes excretion rates of citrate were as low as possible. The conclusion. In patients with diabetes mellitus and concomitant ureterolithiasis there are significant disruptions in the exchange of uric acid and oxalate, with the possibility of correction and complete restoration of urodynamics with the help of the TUСL procedure. Key words: ureterolithiasis, diabetes mellitus, urates, oxalates, minimally invasive methods of lithotripsy.


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