Thiazolidinediones Increase Events of Congestive Heart Failure in Patients with Diabetes Mellitus or with Prediabetes

2008 ◽  
Vol 100 (2) ◽  
pp. 265
1984 ◽  
Vol 108 (1) ◽  
pp. 31-37 ◽  
Author(s):  
Allan S. Jaffe ◽  
James J. Spadaro ◽  
Kenneth Schechtman ◽  
Robert Roberts ◽  
Edward M. Geltman ◽  
...  

1992 ◽  
Vol 25 (2) ◽  
pp. 79-88 ◽  
Author(s):  
Bonpei Takase ◽  
Akira Kurita ◽  
Masayuki Noritake ◽  
Akimi Uehata ◽  
Toshiharu Maruyama ◽  
...  

2009 ◽  
Vol 5 (1) ◽  
pp. 24-27
Author(s):  
Dilip Kumar Sarker ◽  
KMHS Sirajul Haque ◽  
Md Abu Siddique ◽  
Md Khurshed Ahmed ◽  
Fazlur Rahman ◽  
...  

Diabetes mellitus adversely influences the outcome of acute coronary syndrome. This study evaluated the in-hospital outcome of acute coronary syndrome in patients with diabetes mellitus. In this prospective observation study 130 patients with acute coronary syndrome were enrolled. They were divided into diabetic and nondiabetic group. Diabetic patients were taken as case and nondiabetic patients as control. Outcome parameter studied were in-hospital mortality, cardiogenic shock, congestive heart failure, different arrhythmias and recurrent angina. In this study, one third (32%) of the patients were diabetic with mean age 58±10.0 years vs. 53.0±13.6 years in diabetic and nondiabetic group, respectively. Majority of the patients in both groups were male. Congestive heart failure and arrhythmias were more common in case group compared to those in control group (19% vs. 13.6% p=0.424; 23.8% vs. 13.6%, p= 0.148, respectively). Cardiogenic shock developed in 7.1% of diabetic patients and 8% of nondiabetic patients. In hospital mortality was 7.1% and 5.7% in diabetic and nondiabetic group, respectively. Recurrent angina developed only in diabetic patients. Therefore, diabetic patients with acute coronary syndrome encountered more in- hospital adverse outcome.   doi: 10.3329/uhj.v5i1.3437 University Heart Journal Vol. 5, No. 1, January 2009 24-27


Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Scott Mu ◽  
Caitlin W Hicks ◽  
Natalie R Daya ◽  
Randi E Foraker ◽  
Anna Kucharska-newton ◽  
...  

Introduction: Hospitalization is a complex health exposure and the period immediately following acute-care hospitalization is a high-risk state. Self-rated health is a subjective indicator of health and the long-term trends in self-rated health after hospitalization are not well characterized. Hypotheses: 1. Self-rated health decreases after hospitalization, with only partial recovery in the following years. 2. Poor self-rated health after hospitalization is associated with increased mortality. Methods: We analyzed 13,758 participants in the Atherosclerosis Risk in Communities (ARIC) Study with at least 1 hospitalization. Self-rated health was assessed annually and rated on a 4-point scale as follows: “Over the past year, compared to other people your age, would you say that your health has been excellent(=4), good(=3), fair(=2) or poor(=1)?" Using Cox regression and Kaplan-Meier methods, we evaluated mortality after hospitalization for myocardial infarction, congestive heart failure, cerebrovascular disease, pneumonia or diabetes mellitus with complications. Results: The mean self-rated health the year prior to hospitalization was 2.82 and the nadir of self-rated health was 2.62, occurring 1 year after hospitalization (Fig 1a). As compared to “excellent” self-rated health, “poor” self-rated health after any hospitalization was strongly associated with mortality (HR 4.65, 95% CI 4.27-5.07). Corresponding HRs (95% CI) for mortality post-hospitalization were 3.12 (2.30-4.22) for acute myocardial infarction, 3.08 (2.39-3.96) for congestive heart failure, 2.15 (1.43-3.23) for acute cerebrovascular disease, 4.54 (3.39-6.09) for pneumonia, and 3.32 (2.35-4.69) for diabetes mellitus with complications (Fig 1b). Conclusion: Mean self-rated health decreases significantly after hospitalization and worse self-rated health is associated with higher mortality. Self-rated health is an easily obtained patient centered outcome with valuable prognostic information.


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