The antifungal activity of pterocarpans towards Monilinia fructicola

1969 ◽  
Vol 8 (6) ◽  
pp. 971-978 ◽  
Author(s):  
Dawn R. Perrin ◽  
I.A.M. Cruickshank
Keyword(s):  
Antifungal Activity ◽  
Monilinia Fructicola

Postinfectional inhibitors from plants. XXIII. Sesquiterpenoid phytoalexins from fruit capsules of Datura stramonium

1976 ◽  
Vol 54 (1-2) ◽  
pp. 25-29 ◽  
Author(s):  
E. W. B. Ward ◽  
C. H. Unwin ◽  
G. L. Rock ◽  
A. Stoessl
Keyword(s):  
Antifungal Activity ◽  
Detailed Analysis ◽  
Spore Germination ◽  
Pathogenic Fungi ◽  
Datura Stramonium ◽  
Monilinia Fructicola ◽  
Column Chromatographic

Datura stramonium fruit capsules inoculated with Monilinia fructicola or several other non-pathogenic fungi produced diffusates inhibitory to M. fructicola in spore germination assays. Detailed analysis of diffusates that are induced by M. fructicola indicated that they were complex and that antifungal activity was widely distributed through a number of column chromatographic fractions. Four compounds were isolated. These were sesquiterpenes, three of which, lubimin, hydroxylubimin, and capsidiol, have been described from other Solanaceae. The fourth, 2,3-dihydroxygermacrene, is a new compound with moderate antifungal activity but which is of especial interest as a possible precursor of several phytoalexins in the Solanaceae.

scholarly journals Antifungal Activity of Essential Oil and Main Components from Mentha pulegium Growing Wild on the Chilean Central Coast

Agronomy ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 254 ◽  
Author(s):  
Iván Montenegro ◽  
Bastián Said ◽  
Patricio Godoy ◽  
Ximena Besoain ◽  
Carol Parra ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Antifungal Activity ◽  
Essential Oil ◽  
Antifungal Agents ◽  
Research Work ◽  
Gas Chromatography Mass Spectrometry ◽  
Monilinia Fructicola ◽  
Mentha Pulegium ◽  
Main Components

Fungal diseases, both pre- and post-harvest, are currently difficult to control—increased antifungal resistances have further stimulated the search for natural alternatives. The objective of the present research work was to evaluate the antifungal activities of Mentha pulegium essential oil (EO) and its major constituents. The EO was obtained from hydro distillation of fresh leaves, and composition was determined using gas chromatography/mass spectrometry (GC/MS). The main components were identified as pulegone (29.33%), menthol (28.79%), menthone (20.48%), and isopulegol (9.75%). EO and isopulegol exhibited the highest antifungal activity, with half maximal effective concentrations (EC50) inhibiting mycelial activity of Monilinia fructicola at 24.6 µg/mL and 20.8 µg/mL, respectively, and against Botrytis cinerea, at 301.45 µg/mL and 333.84 µg/mL, respectively. These findings could lay the foundation for developing antifungal agents of agricultural value.

Postinfectional inhibitors from plants. XV. Antifungal activity of the phytoalexin orchinol and related phenanthrenes and stilbenes

1975 ◽  
Vol 53 (10) ◽  
pp. 964-971 ◽  
Author(s):  
E. W. B. Ward ◽  
C. H. Unwin ◽  
A. Stoessl
Keyword(s):  
Antifungal Activity ◽  
Effective Dose ◽  
Spore Germination ◽  
Plant Tissue ◽  
Striking Feature ◽  
Monilinia Fructicola ◽  
Higher Plant ◽  
Similar Activity ◽  
Germ Tubes ◽  
Laboratory Synthesis

Orchinol, loroglossol, and several related phenanthrenes and stilbenes obtained by laboratory synthesis were tested for antifungal activity, primarily in spore germination assays against Monilinia fructicola and Phytophthora infestons. The most active stilbene tested was 3,5-dimethoxy-3′-hydroxystilbene (mean effective dose (ED50) 5 × 10−5 M), at least comparable with the reported activity of the stilbene phytoalexin, pinosylvin. All the phenanthrenes and dihydrophenanthrenes tested were active, although assays were complicated by solubility problems. ED50 for orchinol was (5 × 10−5 M) and loroglossol had similar activity against P. infestons. Several phenanthrenes had higher activity, notably dehydroorchinol (ED50 vs. P. infestons 5 × 10−6 M), and warrant further study. A striking feature of the response of the test fungi to the phenanthrenes and dihydrophenanthrenes was the production of distorted and ruptured germ tubes, which may indicate a direct interference with growth processes at the tip. No evidence was obtained for translocation of orchinol in higher plant tissue.

Antifungal activity of a flavonoid-rich fraction from Costus spicatus leaves against dermatophytes

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
DN Silva ◽  
MJ Gonçalves ◽  
MT Amaral ◽  
MT Batista
Keyword(s):  
Antifungal Activity

Antifungal Activity of Brassica rapa-Derived Extracts Against F. oxysporum

Planta Medica ◽  
2013 ◽  
Vol 79 (10) ◽  
Author(s):  
JE Fierro ◽  
P Jiménez ◽  
ED Coy-Barrera
Keyword(s):  
Antifungal Activity ◽  
Brassica Rapa

Therapeutic efficacy of some extracts of hot pepper fruits (Capsicum annuum) and Sumac seeds (Rhus coriaria) on the growth of some isolated dermatophytes species

2018 ◽  
Vol 1 (3) ◽  
pp. 52-62
Author(s):  
Sara Omran ◽  
Abdulghani Alsamarai ◽  
Firas Razzzaq
Keyword(s):  
Antifungal Activity ◽  
Fungal Infection ◽  
Aqueous Extract ◽  
Plant Extracts ◽  
Therapeutic Efficacy ◽  
Diffusion Method ◽  
Quantitative Detection ◽  
Hot Pepper ◽  
Alcoholic Extract ◽  
Dermatology Clinic

Background: Fungal infections are one of the common skin diseases with difficulty in their treatment approach. The present efficient drugs for fungal infection are limited. Aim: To determine the therapeutic efficacy of plant extracts as alternative antifungal agents. Materials and methods: 100 clinical samples [68 from female and 32 from male] were collected during the period from March to July 2017 from subjects attending Dermatology Clinic in Salah Uldean General Hospital. Fungal infection was diagnosed with using KOH wet preparation. Fungal species identified by using conventional approach. The active ingredients existing in the plant extracts were detected and analyzed through qualitative and quantitative detection technique of chemical compounds using a high performance liquid chromatographic device (HPLC). Agar diffusion method was used to determine antifungal activity of plant extracts. Results: Direct microscopic examination showed that there were (75%) positive samples, while culture shows (67%) positive samples. The isolated dermatophytes belong to Epidermophyoton, Microsporum, and Trichophyton genus. The predominant dermatophytes were T. rubrum (25%) species. The highest frequency of infection was in the age group of 11-20 years. The sensitivity of the tested fungi to the aqueous and alcoholic plant extracts varies. Alcoholic extract of the hot pepper plant was more effective as antifungal than the aqueous extract of the same plant. However, aqueous hot pepper extracts was more effective against T. mentagrophyte than that of alcoholic extract. Additionally, alcoholic Sumac extract shows higher efficacy that aqueous extract. Conclusion: Hot pepper and Sumac extracts show antifungal activity against Microsporum canis, Trichophyton rubrum and T. mentagrophyte.

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