Naturally Occurring Food Toxicants: Phenolic Substances of Plant Origin Common in Foods

1981 ◽  
pp. 149-242 ◽  
Author(s):  
Vernon L. Singleton
Keyword(s):  
Plant Origin ◽  
Naturally Occurring ◽  
Phenolic Substances ◽  
Food Toxicants

A REVIEW ON RECENT ADVANCES IN CHEMISTRY, SYNTHESIS AND BIOLOGICAL APPLICATIONS OF ISATIN DERIVATIVES

2018 ◽  
pp. 16-22
Author(s):  
Shukla PK ◽  
Singh MP ◽  
Patel R
Keyword(s):  
Heterocyclic Compounds ◽  
Biologically Active ◽  
Biological Applications ◽  
Plant Origin ◽  
Recent Past ◽  
Pharmacological Activities ◽  
Naturally Occurring ◽  
Recent Advances ◽  
Biological Aspects ◽  
Isatin Derivatives

Indole and its derivatives have engaged a unique place in the chemistry of nitrogen heterocyclic compounds. The recognition of the plant growthhormone, heteroauxin, the significant amino acids, tryptamine & tryptophan and anti-inflammatory drug, indomethacine are the imperativederivatives of indole which have added stimulus to this review work. Isatin (1H-indole-2,3-dione), an indole derivative of plant origin. Althoughit is a naturally occurring compound, but was synthesized by Erdmann and Laurent in 1840 before it was found in nature. Isatin is a versatileprecursor for many biologically active molecules and its diversified nature makes it a versatile substrate for further modifications. It is concernedin many pharmacological activities like anti-malarial, antiviral, anti-allergic, antimicrobial etc; isatin and its derivatives have been also found todemonstrate promising outcomes against various cancer cell lines. This review provides a brief overview on the recent advances and futureperspectives on chemistry and biological aspects of isatin and its derivatives reported in the recent past.

scholarly journals Leishmania infantum arginase: biochemical characterization and inhibition by naturally occurring phenolic substances

2019 ◽  
Vol 34 (1) ◽  
pp. 1100-1109 ◽  
Author(s):  
Andreza R. Garcia ◽  
Danielle M. P. Oliveira ◽  
Ana Claudia F. Amaral ◽  
Jéssica B. Jesus ◽  
Ana Carolina Rennó Sodero ◽  
...  
Keyword(s):  
Leishmania Infantum ◽  
Biochemical Characterization ◽  
Naturally Occurring ◽  
Phenolic Substances

scholarly journals Quantifying the inovation of cosmetic formulations that contains phenolic rich fruit extracts as fotoprotective bioactives

2021 ◽  
Vol 20 (1) ◽  
pp. 5
Author(s):  
Milleno Dantas Mota ◽  
Fábio Alexandre Chinalia ◽  
Lidércia Cavalcanti Ribeiro Cerqueira e Silva
Keyword(s):  
Uv Light ◽  
Industrial Sector ◽  
European Patent ◽  
Cosmetic Products ◽  
Fruit Extracts ◽  
Naturally Occurring ◽  
Time Period ◽  
Phenolic Substances ◽  
Herbal Cosmetics ◽  
The Cost

<p><strong>Introduction</strong>: sunscreen is a cosmetic used to protect human skin from the deleterious effects of UV radiation and thus minimize the risks of developing skin cancer. Extracts produced from fruits, such as Abiu, Guava, Rambutan and Grape, have significant concentrations of chromophores and phenolic substances that have the ability to absorb UV light and neutralize free radicals. The production of cosmetics from naturally occurring substances with such activities will be of great importance for Brazilian industry and could reduce the cost of production, given the large existing biodiversity in the country. <strong>Objectives</strong>: carry out a patent search for formulations and cosmetic products that contains phenolic rich fruit extracts as photoprotective and antioxidant bioactives. <strong>Methodology</strong>: a survey of patents was carried out in the database of the National Institute of Intellectual Property (INPI) and the European Patent Office (EPO), covering a time period between 2008 and 2018, using a combination of keywords related to herbal cosmetics and sunscreens. <strong>Results</strong>: this research identifies a significant number of patents related to plant extract in association with sunscreen product, however, no patent filings were identified for cosmetic products containing extracts of the evaluated fruits, either alone or in combination, for photoprotective and antioxidant purposes. <strong>Conclusion</strong>: the Brazilian and international market for sun care products moves millions to billions of dollars annually and have a significant annual growth prospect. Considering the great biodiversity existing in the country, the production of cosmetics from naturally occurring substances with such activities will be of great importance for the Brazilian industrial sector.</p>

scholarly journals ANALYSIS OF NATURALLY OCCURRING PENOLIC COMPOUNDS OF THE GENERA CLINOPODIUM L. , HYMENOCRATER FISH & C. A. MEY. AND MELISSA L.

2016 ◽  
Vol 47 (1) ◽  
Author(s):  
AL-Zubaidy & et al.
Keyword(s):  
Salicylic Acid ◽  
Phenolic Compound ◽  
High Performance ◽  
Kurdistan Region ◽  
Phenolic Profile ◽  
Naturally Occurring ◽  
Phenolic Substances ◽  
Hplc Technique ◽  
First Time ◽  
Dimethyl Phenol

Six taxa of Lamiaceae family including three taxa of the genus Clinopodium L. (C. vulgare subsp. vulgareL., C. umbrosum (M. B.) C. Koch. and C. congstum Boiss. & Hausskn ex. Boiss. ) and two of the genus Hymenocrater Fish. & C. A.  Mey. (H,longiflora Benth. H. bituminosus Fish & C. A. Mey) and one of the genus Melissa (M.officinalis subsp.fficinalis L.) were studied in order to evaluate their phenolic profile ,as these taxa were studied in such detail for the first time in Kurdistan region of Iraq . The examined phenolic substances which studied in these taxa include: Caffeine, Coumarin, Eugenol Estragole(4- Allyl anisole), 2-6 Dimethyl phenol, Salicylic acid and P-Cresol, by using high performance liquid chromatography (HPLC) technique. The results showed that the most abundant phenolic compound were: Caffeine and 2-6Dimethyl phenol which found in all the studied taxa, followed by Eugenol and Salicylic acid which found in five of the six studied taxa, whereas the less prevalent phenolic compounds were )Coumarin and Estragole(4- Allyl anisole),which found in just two of the studied taxa. The deference in distribution of the phenolic compound in the studied taxa can be utilized to differentiate between them in studies of genetic diversity and chemotaxonomy as it can be possible to distinguish between the genera Clinopodium, Hymenocrater and Melissa beside the distinguish between the taxa of the same genus ( Clinopodium ), using phenolic profile.

scholarly journals Natural Product Triterpenoids and Their Semi-Synthetic Derivatives with Potential Anticancer Activity

Planta Medica ◽  
2019 ◽  
Vol 85 (11/12) ◽  
pp. 802-814 ◽  
Author(s):  
Yulin Ren ◽  
A. Douglas Kinghorn
Keyword(s):  
Anticancer Agents ◽  
Higher Plants ◽  
Structural Diversity ◽  
Chemotherapeutic Agents ◽  
Plant Origin ◽  
Related Activity ◽  
Pentacyclic Triterpenoids ◽  
Naturally Occurring ◽  
Structure Activity ◽  
Synthetic Derivatives

Triterpenoids are distributed widely in higher plants and are of interest because of their structural diversity and broad range of bioactivities. In particular, there is a very large literature on the propensity of a variety of triterpenoids to act as potential anticancer agents. In the present review, the anticancer potential is summarized for naturally occurring triterpenoids and their semi-synthetic derivatives, including examples of lupane-, oleanane-, ursane-, and cucurbitane-type pentacyclic triterpenoids, along with dammarane-type tetracyclic triterpenes including ginsenosides and their sapogenins and dichapetalins, which have been characterized as antitumor leads from higher plants. Preliminary structure-activity relationships and reported mechanisms of the antineoplastic-related activity are included. Prior studies for triterpenoids of plant origin are supportive of additional work being conducted on the more detailed biological and mechanistic evaluation for the progression of this type of natural products as possible cancer chemotherapeutic agents.

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