MON-PP025: Moderate Physical Activity Reduces Negative Association between Skeletal Muscle Mass and Aging in Middle Aged Men

2015 ◽  
Vol 34 ◽  
pp. S136-S137
Author(s):  
R. Iacone ◽  
C. Scanzano ◽  
O. Russo ◽  
A. D’Isanto ◽  
E. Pastore ◽  
...  
Author(s):  
Harshvardhan Singh ◽  
Bethany A. Moore ◽  
Roshita Rathore ◽  
Michael G. Bemben ◽  
Debra A. Bemben

The authors examined sex-specific relationships between fat mass index (FMI), android/gynoid (A/G) fat ratio, relative skeletal muscle mass index, and Bone-Specific Physical Activity Questionnaire derived bone-loading scores (BLSs) in middle-aged and older adults (men, n = 27; women, n = 33; age = 55–75 years). The FMI, A/G fat ratio, and relative skeletal muscle mass index were estimated by dual-energy X-ray absorptiometry. The Bone-Specific Physical Activity Questionnaire was used to assess: (a) BLSpast (age 1 until 12 months before the study visit), (b) BLScurrent (last 12 months), and (c) BLStotal (average of [a] and [b]) scores. Separate multiple linear regression analysis of (a) age, FMI, and relative skeletal muscle mass index and (b) age, height, and A/G fat ratio versus BLS revealed that FMI and A/G fat ratio were negatively associated with BLSpast and BLStotal (p < .05) in women only. Adiposity and, specifically, central adiposity is negatively related to bone-loading physical activity in middle-aged and older women.


2017 ◽  
Vol 14 (11) ◽  
pp. 1054-1064 ◽  
Author(s):  
Hye Eun Yoon ◽  
Yunju Nam ◽  
Eunjin Kang ◽  
Hyeon Seok Hwang ◽  
Seok Joon Shin ◽  
...  

2008 ◽  
Vol 40 (Supplement) ◽  
pp. S393
Author(s):  
Colleen M. McCracken ◽  
Louisa D. Raisbeck ◽  
Jonathon L. Stickford ◽  
Sandra Tecklenberg ◽  
Jeanne D. Johnston ◽  
...  

2005 ◽  
Vol 37 (Supplement) ◽  
pp. S301
Author(s):  
Taishi Midorikawa ◽  
Takashi Abe ◽  
Kiyoshi Sanada ◽  
Charles F. Kearns ◽  
Tetsuo Fukunaga

2009 ◽  
Vol 106 (6) ◽  
pp. 2040-2048 ◽  
Author(s):  
René Koopman ◽  
Luc J. C. van Loon

Aging is accompanied by a progressive loss of skeletal muscle mass and strength, leading to the loss of functional capacity and an increased risk of developing chronic metabolic disease. The age-related loss of skeletal muscle mass is attributed to a disruption in the regulation of skeletal muscle protein turnover, resulting in an imbalance between muscle protein synthesis and degradation. As basal (fasting) muscle protein synthesis rates do not seem to differ substantially between the young and elderly, many research groups have started to focus on the muscle protein synthetic response to the main anabolic stimuli, i.e., food intake and physical activity. Recent studies suggest that the muscle protein synthetic response to food intake is blunted in the elderly. The latter is now believed to represent a key factor responsible for the age-related decline in skeletal muscle mass. Physical activity and/or exercise stimulate postexercise muscle protein accretion in both the young and elderly. However, the latter largely depends on the timed administration of amino acids and/or protein before, during, and/or after exercise. Prolonged resistance type exercise training represents an effective therapeutic strategy to augment skeletal muscle mass and improve functional performance in the elderly. The latter shows that the ability of the muscle protein synthetic machinery to respond to anabolic stimuli is preserved up to very old age. Research is warranted to elucidate the interaction between nutrition, exercise, and the skeletal muscle adaptive response. The latter is needed to define more effective strategies that will maximize the therapeutic benefits of lifestyle intervention in the elderly.


2017 ◽  
Vol 20 (5) ◽  
pp. 660-669 ◽  
Author(s):  
Carine Fernandes de Souza ◽  
Mariana Carmem Apolinário Vieira ◽  
Rafaela Andrade do Nascimento ◽  
Mayle Andrade Moreira ◽  
Saionara Maria Aires da Câmara ◽  
...  

Abstract Objective: to analyze the relationship between handgrip strength and lower limb strength and the amount of segmental skeletal muscle mass in middle-aged and elderly women. Methods: an observational, cross-sectional, observational study of 540 women aged between 40 and 80 years in the cities of Parnamirim and Santa Cruz, Rio Grande do Norte, was performed. Sociodemographic data, anthropometric measurements, handgrip dynamometry, knee flexors and extensors of the dominant limbs, as well as the segmental muscle mass of the limbs were evaluated. Data were analyzed using Student's t-Test, Chi-square test, Effect Size and Pearson's Correlation (CI 95%). Results: there were statistically significant weak and moderate correlations between handgrip strength and upper limb muscle mass, knee flexion strength and lower limb muscle mass, and between knee extension strength and lower limb muscle mass for the age groups 40-59 years and 60 years or more (p<0.05). Conclusions: muscle strength correlates with skeletal muscle mass. It could therefore be an indicator of the decrease in strength. It is not the only such indicator, however, as correlations were weak and moderate, which suggests the need for more studies on this theme to elucidate which components may also influence the loss of strength with aging.


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