Specific immune response to Phleum pratense plant profilin in atopic patients and control subjects

Vaccination has a great impact on the prevention and control of infectious diseases. Nanoparticles can deliver immunoactive biomolecules to induce a virus-specific immune response.

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Study the Non-Specific Immune Response and Prevalence of Rotavirus Causing Diarrhea in Infants

Al-Qadisiyah Journal of Veterinary Medicine Sciences ◽

10.29079/vol10iss2art160 ◽

2011 ◽

Vol 10 (2) ◽

pp. 94

Author(s):

A. M. Al-khafagi, S. A. Almashta and I. H. Al-yassari

Keyword(s):

Immune Response ◽

Statistical Analysis ◽

Breast Feeding ◽

Included Study ◽

Specific Immune Response ◽

Control Group ◽

Mixed Feeding ◽

Rotavirus Infection ◽

Infantile Diarrhea ◽

And Control

In this study we used Rapid chromatography immunoassay for the qualitative detection of rotavirus in human feces specimens .this study included (50) blood and feces specimens (16)was acute infantile diarrhea with rotavirus infection and (22) acute infantile diarrhea without rotavirus infection and(12)as a control group . distribution of acute infantile diarrhea with rotavirus infection, acute infantile diarrhea without rotavirus infection and control group according to the sex was (56.25% , 54.55% , 50%) in male respectively but it was ( 43.75% , 45.45% , 50% ) in female respectively. The statistical analysis was significant P<0.05 in acute infantile diarrhea with rotavirus infection in comparing with control group .the distribution of acute infantile diarrhea with rotavirus infection, acute infantile diarrhea without rotavirus infection and control group according to the type of feeding in breast feeding was ( 37.5%, 40.91%,50%) respectively but it was ( 62.5%, 59.09%, 50 % ) in mixed feeding respectively. The statistical analysis was high significant P<0.05 in mixed feeding in comparing with breast feeding . also this study included study the level of non–specific immune response by using differential leukocytes counts [DLC] The statistical analysis of percentage of neutrophils ,lymphocytes and monocytes was lower significant P<0.05 in acute infantile diarrhea with rotavirus infection and acute infantile diarrhea without rotavirus infection in comparing with control group .

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Immune response to Aβ-peptides in peripheral blood from patients with Alzheimer's disease and control subjects

Neuroscience Letters ◽

10.1016/j.neulet.2003.10.071 ◽

2004 ◽

Vol 355 (3) ◽

pp. 226-230 ◽

Cited By ~ 26

Author(s):

Laurence Baril ◽

Ludovic Nicolas ◽

Bernard Croisile ◽

Pierre Crozier ◽

Catherine Hessler ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Immune Response ◽

Peripheral Blood ◽

Aβ Peptides ◽

Control Subjects ◽

And Control

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Comirnaty-Elicited and Convalescent Sera Recognize Different Spike Epitopes

Vaccines ◽

10.3390/vaccines9121419 ◽

2021 ◽

Vol 9 (12) ◽

pp. 1419

Author(s):

Sascha Hein ◽

Nuka Ivalu Benz ◽

Jonathan Eisert ◽

Marie-Luise Herrlein ◽

Doris Oberle ◽

...

Keyword(s):

Immune Response ◽

Specific Antibody ◽

Protein A ◽

Specific Immune Response ◽

Spike Protein ◽

Peptide Array ◽

Antibody Diversity ◽

Central Helix ◽

Linear Epitopes ◽

And Control

Many of the approved SARS-CoV-2 vaccines are based on a stabilized variant of the spike protein. This raises the question of whether the immune response against the stabilized spike is identical to the immune response that is elicited by the native spike in the case of a SARS-CoV-2 infection. Using a peptide array-based approach, we analysed the binding of antibodies from Comirnaty-elicited, convalescent, and control sera to the peptides covering the spike protein. A total of 37 linear epitopes were identified. A total of 26 of these epitopes were almost exclusively recognized by the convalescent sera. Mapping these epitopes to the spike structures revealed that most of these 26 epitopes are masked in the pre-fusion structure. In particular, in the conserved central helix, three epitopes that are only exposed in the post-fusion conformation were identified. This indicates a higher spike-specific antibody diversity in convalescent sera. These differences could be relevant for the breadth of spike-specific immune response.

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The Effects of a Neutral Stimulus (Buzzer) on Motor Responses and Disfluencies in Normal Speakers

Journal of Speech and Hearing Research ◽

10.1044/jshr.1201.179 ◽

1969 ◽

Vol 12 (1) ◽

pp. 179-184 ◽

Cited By ~ 7

Author(s):

Richard R. Martin ◽

Gerald M. Siegel

Keyword(s):

College Students ◽

Neutral Stimulus ◽

Motor Responses ◽

Control Subjects ◽

And Control ◽

Speaking Task

Seventy-two college students were divided into three groups: Button Push-Speech (BP-S), Speech-Button Push (S-BP), and Control. BP-S subjects pushed one of two buttons on signal for 8 min. During the last 4 min, depression of the criterion button caused a buzzer to sound. After the button-push task, subjects spoke spontaneously for 30 min. During the last 20 min, the buzzer was presented contingent upon each disfluency. S-BP subjects were run under the same procedures, but the order of button-push and speech tasks was reversed. Control subjects followed the same procedures as S-BP subjects, but no buzzer signal was presented at any time. Both S-BP and BP-S subjects emitted significantly fewer disfluencies during the last 20 min (Conditioning) than during the first 10 min (Baserate) of the speaking task. The frequency of disfluencies for Control subjects did not change significantly from Baserate to Conditioning. In none of the three groups did the frequency of pushes on the criterion button change significantly from minute to minute throughout the 8-min button-push session.

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Tests for Platelet Changes, Acute Phase Reactants and Serum Lipids in Diabetes mellitus and Peripheral Vascular Disease

Thrombosis and Haemostasis ◽

10.1055/s-0038-1657283 ◽

1982 ◽

Vol 48 (03) ◽

pp. 289-293 ◽

Cited By ~ 17

Author(s):

B A van Oost ◽

B F E Veldhuyzen ◽

H C van Houwelingen ◽

A P M Timmermans ◽

J J Sixma

Keyword(s):

Diabetes Mellitus ◽

Vascular Disease ◽

Peripheral Vascular Disease ◽

Acute Phase ◽

Serum Lipids ◽

Diabetic Patients ◽

Peripheral Vascular ◽

Acute Phase Reactants ◽

Control Subjects ◽

And Control

SummaryPlatelets tests, acute phase reactants and serum lipids were measured in patients with diabetes mellitus and patients with peripheral vascular disease. Patients frequently had abnormal platelet tests and significantly increased acute phase reactants and serum lipids, compared to young healthy control subjects. These differences were compared with multidiscriminant analysis. Patients could be separated in part from the control subjects with variables derived from the measurement of acute phase proteins and serum lipids. Platelet test results improved the separation between diabetics and control subjects, but not between patients with peripheral vascular disease and control subjects. Diabetic patients with severe retinopathy frequently had evidence of platelet activation. They also had increased acute phase reactants and serum lipids compared to diabetics with absent or nonproliferative retinopathy. In patients with peripheral vascular disease, only the fibrinogen concentration was related to the degree of vessel damage by arteriography.

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