Efficacy of fenbendazole granules and pyrantel pamoate suspension against Toxocara canis in greyhounds housed in contaminated runs

1999 ◽  
Vol 82 (4) ◽  
pp. 311-315 ◽  
Author(s):  
Michael W Dryden ◽  
Robert K Ridley
Keyword(s):  
Toxocara Canis ◽  
Pyrantel Pamoate

scholarly journals The anti-parasitic efficacy of ivermectin and pyrantel pamoate compound against canine Toxocara canis and Trichuris vulpis

2011 ◽  
Vol 51 (4) ◽  
pp. 289-295
Author(s):  
Heejeong Youn ◽  
Jeong Chan Ra ◽  
Byung Ki Kim ◽  
Bokyoung Bae ◽  
Yong Suk Lim ◽  
...  
Keyword(s):  
Toxocara Canis ◽  
Pyrantel Pamoate ◽  
Trichuris Vulpis

scholarly journals Effectiveness of a modern antiparasitic agent for deworming in domestic animals

2021 ◽  
Vol 11 (1) ◽  
pp. 10-17
Author(s):  
A.P. Paliy ◽  
R.P. Petrov ◽  
A.P. Palii
Keyword(s):  
Potato Starch ◽  
Significant Proportion ◽  
Toxocara Canis ◽  
Domestic Animals ◽  
Parasitic Diseases ◽  
Health Issues ◽  
Dipylidium Caninum ◽  
Pyrantel Pamoate ◽  
Promising Area ◽  
Antiparasitic Agents

Parasitic diseases continue to account for a significant proportion of overall morbidity in many parts of the world despite improved living conditions and increased awareness of health issues. The creation of innovative veterinary antiparasitic agents is a promising area of modern veterinary pharmacy. The pathogens Dipylidium caninum, Ancylostoma caninum, Toxocara canis, Toxocaris leonina were identified in the study of stray dogs (n=12). Eggs of Dipylidium caninum, Toxocara mystax, and Toxocaris leonina were found during cats' examination (n=15). Both mono and mixed invasions have been diagnosed in animals. We established that the floor and inventory were contaminated with exogenous forms of helminths at an extent of 100% after keeping animals in the shelter's enclosures. An innovative antiparasitic agent was used to treat animals. One tablet (0.5 g) contains the following active ingredients such as pyrantel pamoate (150±0.5 mg), praziquantel (50±0.5 mg), and auxiliary substances (lactose, microcrystalline cellulose, calcium stearate, sodium chloride, food flavoring "meat", povidone K-30 and potato starch). We estimated high antiparasitic agents' extensive efficiency (100%) at mono and mixed invasions in dogs and cats.

scholarly journals EFICÁCIA DE DOIS SISTEMAS DE TRATAMENTO ANTI-HELMÍNTICO EM FILHOTES DE CÃES COM INFECÇÃO NATURAL

2004 ◽  
Vol 9 (1) ◽  
Author(s):  
F.R. MORAES ◽  
V. THOMAZ SOCCOL ◽  
E.A. CASTRO ◽  
L. HENNIG ◽  
J.T. PEREIRA ◽  
...  
Keyword(s):  
Natural Infection ◽  
Toxocara Canis ◽  
Treatment Protocols ◽  
Treatment Groups ◽  
The Third ◽  
Pyrantel Pamoate ◽  
Two Systems ◽  
Group 2 ◽  
Group 1

O objetivo do presente trabalho foi testar dois esquemas de tratamento para o combate da parasitose gastrintestinal em filhotes de cães recém-desmamados. Foram estabelecidos dois grupos de tratamento, ambos tratados com uma suspensão pamoato de pirantel e oxantel: grupo 1 - quatro desverminações com intervalos de 15 dias e grupo 2 -três desverminações, nos dias 0, 5 e 25 pós desmame. O primeiro tratamento apresentou redução de 98,2 % no número de ovos por grama de fezes (opg) de Toxocara canis, após a primeira desverminação. Cem por cento de redução de opg foi obtido após o segundo tratamento. No tratamento 2, foi obtido um resultado semelhante após três tratamentos. Para ovos de Ancylostoma sp. a formulação mostrou eficácia após a primeira dose para ambos os tratamentos preconizados. Estes resultados indicam que os esquemas de tratamento propostos poderiam ser adotados para combate das infecções por estes parasitas em animais recém-desmamados. Comparison of the efficacy of two systems of antihelminthic treatment in puppies with natural infection Abstract This work was developed to test two treatment outlines for gastrointestinal parasitosis control in weaned puppies. Two treatment groups were established, both treated with oxantel and pyrantel pamoate suspension: group 1 (four doses with 15-days intervals) and group 2 (three doses, at zero, 5th and 25th days). The first treatment presented reduction of 98.2 % on the number of eggs of Toxocara canis per gram of feces (epg) after the first dose. Complete epg reduction was observed after the second treatment, 15 days later. Similar result was obtained after the third dose for the treatment 2. Both treatment protocols showed effectiveness for eggs of Ancylostoma sp. after the first dose. These results indicate that both treatment outlines could be applied for the roundworm and the hookworm control in recently-weaned puppies.

Prevalence of Toxoplasma gondii and Toxocara canis among Myositis Patients in Southwest of Iran

2019 ◽  
Vol 20 ◽  
Author(s):  
Jasem Saki ◽  
Karim Mowla ◽  
Reza Arjmand ◽  
Forough Kazemi ◽  
Somayeh Fallahizadeh
Keyword(s):  
Toxoplasma Gondii ◽  
Nested Pcr ◽  
Healthy Subjects ◽  
Toxocara Canis ◽  
Control Group ◽  
Igg Antibodies ◽  
Healthy Individuals ◽  
High Prevalence ◽  
Acute Toxoplasmosis ◽  
Southwest Of Iran

Introduction: Parasitic myositis is caused by some parasites such as T. gondii and T. canis. So, the aim of the study was to evaluate the prevalence T. gondii and T. canis in patients with myositis and healthy individuals. Methods: A total of 108 samples were randomly selected as the control (54 healthy individuals) and test (54 myositis patients) groups. IgG and IgM antibodies against T. gondii and IgG antibodies against T. canis were measured by the ELISA. The detection of chronic and acute toxoplasmosis was performed by the ELISA IgG avidity. The presence of T. gondii in blood was evaluated by the nested-PCR. Results: Of 108, 33 (30.6%) cases were detected positive for IgG against T. gondii that 19 (35.2%) and 14 (25.9%) were observed in myositis patients and healthy individuals, respectively (P=0.296). Of 19 positive cases, 12 (63.2%) and 7 (36.8%) cases were detected as chronic and acute toxoplasmosis, respectively, while, all positive cases in the control group had chronic toxoplasmosis (P=0.013). One (1.9%) sample was detected positive for anti- Toxoplasma gondii IgM and two (3.7%) samples were found positive for IgG against T. canis by the ELISA that these positive cases were observed only in myositis patients (P=1.000 P=0.495, respectively). B1 T. gondii gene was amplified in 12 (63.2%) and 1 (7.1%) in myositis patients and healthy subjects (P=0.001). Conclusions: Our findings showed that there was a relatively high prevalence of acute toxoplasmosis in myositis patients in comparison with the control subjects in southwest of Iran.

A comparison of the protein constituents of the major body compartments of the dog roundworm, Toxocara canis

2007 ◽  
Vol 150 (1-2) ◽  
pp. 111-115 ◽  
Author(s):  
Tiffany Sun ◽  
Mary L. Bellosa ◽  
Araceli Lucio-Forster ◽  
Dean S. Ho ◽  
Dwight D. Bowman
Keyword(s):  
Toxocara Canis ◽  
Body Compartments

Human density, economic level and frequency of canine helminths in Buenos Aires

2021 ◽  
Vol 95 ◽  
Author(s):  
D. Rubel ◽  
N. Flaibani
Keyword(s):  
Linear Models ◽  
Buenos Aires ◽  
Toxocara Canis ◽  
The Other ◽  
Green Spaces ◽  
Cross Sectional ◽  
Independent Variables ◽  
Economic Level ◽  
Faecal Samples ◽  
Human Density

Abstract The aim of this study was to explore through cross-sectional study the variation in the prevalence of parasitic helminths in canine faeces collected from green spaces of Buenos Aires according to the human density (HD) and economic level (EL) in the surroundings. HD and EL were considered as independent variables with three categories each. Twenty public squares (one hectare of surface) were randomly selected for each existing combination of the two independent variables. Ten random samples of fresh canine faeces were obtained in each square and analysed for helminths by the sedimentation and flotation techniques. The prevalence for each of the species was analysed using generalized linear models (GLM). The prevalence was modelled with a binomial error distribution and a logit link function. Helminth eggs were detected in 45 out of the 200 (22.5%) faecal samples collected and in 18 of the 20 green spaces sampled. The species observed were Ancylostoma caninum (13% of samples), Trichuris vulpis (8%) and Toxocara canis (4.5%). The GLM indicated that the prevalence of A. caninum in the slum areas (very high HD and very low EL) was higher than that in the other areas studied. However, the HD seemed to contribute more than the EL to the variations in the prevalence of A. caninum in faecal samples. The GLM showed no differences in the prevalence of the other parasite species for the different levels of the independent variables.

Development of a low-cost copro-LAMP assay for simultaneous copro-detection of Toxocara canis and Toxocara cati

Parasitology ◽  
2021 ◽  
pp. 1-8
Author(s):  
Héctor Gabriel Avila ◽  
Marikena Guadalupe Risso ◽  
Paula Ruybal ◽  
Silvia Analía Repetto ◽  
Marcos Javier Butti ◽  
...  
Keyword(s):  
Low Cost ◽  
Lamp Assay ◽  
Toxocara Canis ◽  
Toxocara Cati

Abstract

scholarly journals PSV-37 Reemergence of cyathostomins species demonstrates anthelmintic resistance following drug administration in horses

2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 335-335
Author(s):  
Alexa C Johnson ◽  
Amy S Biddle
Keyword(s):  
Anthelmintic Resistance ◽  
Macrocyclic Lactones ◽  
Number Of Species ◽  
Molecular Approaches ◽  
Pyrantel Pamoate ◽  
Drug Classes ◽  
Blast Database ◽  
Resistance Patterns ◽  
Near Future ◽  
Ncbi Blast

Abstract Arbitrary administration of anthelmintics to control equine gastrointestinal worms has led to increased resistance to the three broad-spectrum drug classes; benzimidazoles, tetrahydropyrimidines, and macrocyclic lactones. With little promise of new drug classes to target cyathostomins being introduced to the market in the near future, anthelmintic drugs must be administered judiciously to prevent complete anthelmintic parasite resistance. The objective of this study is to determine the reemergence rate of cyathostomins following three commercial horse dewormers during summer. Nine horses housed at two locations were enrolled to the study and was repeated June–September through 2017–2019. Horses were removed from the study if sequencing failed due to low egg recovery for more than 50% of the timepoints. Ivermectin (macrocyclic lactones; n = 6), Moxidectin (macrocyclic lactones; n = 8) and Strongid (pyrantel pamoate; n = 8) were administered to horses and fecal samples were collected every 14d for 98d. Samples were tested using fecal egg counts with a modified McMaster technique and 18S rRNA profiling of the V5.8 and ITS1 regions. Sequences were clustered and taxonomy was assigned against a custom NCBI Blast+ database with the aligned sequences of 19 cyathostomins. Data were analyzed using presence/absence methods in R studio. Treatment and Day significantly impacted the average number of species present (P < 0.001). Moxidectin had the lowest number of species present followed by Strongid then Ivermectin (7.14, 10.17, 11.09, respectively). Equine shedder status had no effect on the average number of species present (P > 0.05). Six species, CO. labiatus, CS. catinatum, CY. auriculatus, CY. elongatus, CT. goldi and CT. longibursatus, showed resistance to the three treatments (P > 0.05). Moxidectin was the most effective at eradicating cyathostomins infestations (P < 0.05). Identifying resistance patterns at the species level will enable mechanistic molecular approaches to determine anthelmintic resistance in cyathostomins.

Infectivity and pathogenicity of 14-month-cultured embryonated eggs of Toxocara canis in mice

2003 ◽  
Vol 113 (2) ◽  
pp. 145-155 ◽  
Author(s):  
Chia-Kwung Fan ◽  
Yun-Ho Lin ◽  
Wen-Yuan Du ◽  
Kua-Eyre Su
Keyword(s):  
Toxocara Canis
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