scholarly journals Effectiveness of a modern antiparasitic agent for deworming in domestic animals

2021 ◽  
Vol 11 (1) ◽  
pp. 10-17
Author(s):  
A.P. Paliy ◽  
R.P. Petrov ◽  
A.P. Palii
Keyword(s):  
Potato Starch ◽  
Significant Proportion ◽  
Toxocara Canis ◽  
Domestic Animals ◽  
Parasitic Diseases ◽  
Health Issues ◽  
Dipylidium Caninum ◽  
Pyrantel Pamoate ◽  
Promising Area ◽  
Antiparasitic Agents

Parasitic diseases continue to account for a significant proportion of overall morbidity in many parts of the world despite improved living conditions and increased awareness of health issues. The creation of innovative veterinary antiparasitic agents is a promising area of modern veterinary pharmacy. The pathogens Dipylidium caninum, Ancylostoma caninum, Toxocara canis, Toxocaris leonina were identified in the study of stray dogs (n=12). Eggs of Dipylidium caninum, Toxocara mystax, and Toxocaris leonina were found during cats' examination (n=15). Both mono and mixed invasions have been diagnosed in animals. We established that the floor and inventory were contaminated with exogenous forms of helminths at an extent of 100% after keeping animals in the shelter's enclosures. An innovative antiparasitic agent was used to treat animals. One tablet (0.5 g) contains the following active ingredients such as pyrantel pamoate (150±0.5 mg), praziquantel (50±0.5 mg), and auxiliary substances (lactose, microcrystalline cellulose, calcium stearate, sodium chloride, food flavoring "meat", povidone K-30 and potato starch). We estimated high antiparasitic agents' extensive efficiency (100%) at mono and mixed invasions in dogs and cats.

scholarly journals Різноманіття паразитів м’ясоїдних тварин на території м. Дніпропетровськ

2011 ◽  
Vol 2 (2) ◽  
pp. 3-7 ◽  
Author(s):  
О. О. Boyko ◽  
L. I. Faly ◽  
V. V. Brygadyrenko
Keyword(s):  
Toxoplasma Gondii ◽  
Strongyloides Stercoralis ◽  
Toxocara Canis ◽  
Spirocerca Lupi ◽  
Dipylidium Caninum ◽  
Trichuris Vulpis

In Dnipropetrovsk sity (Ukraine, Dnipropetrovsk region) in carnivorous animals 10 species of parasites (helminths and coccidia) were found: Uncinaria sp., Ancylostoma sp., Dictyocaulus immitis (Nematoda, Strongylata), Strongyloides stercoralis (Nematoda, Rhabditata), Spirocerca lupi (Nematoda, Spirurata), Toxocara canis (Nematoda, Ascaridata), Trichuris vulpis (Nematoda, Trichurata), Dipylidium caninum (Cestoda, Hymenolepidata), Cystoisospora sp. and Toxoplasma gondii (Sporozoa, Coccidia). In soil S. stercoralisand Uncinaria sp. weredominanted. In most carnivorous animals registered in L. Globa park and T. Shevchenko park the S. stercoralisand Uncinaria sp., Cystoisosporasp. and T. gondii were found.

scholarly journals The anti-parasitic efficacy of ivermectin and pyrantel pamoate compound against canine Toxocara canis and Trichuris vulpis

2011 ◽  
Vol 51 (4) ◽  
pp. 289-295
Author(s):  
Heejeong Youn ◽  
Jeong Chan Ra ◽  
Byung Ki Kim ◽  
Bokyoung Bae ◽  
Yong Suk Lim ◽  
...  
Keyword(s):  
Toxocara Canis ◽  
Pyrantel Pamoate ◽  
Trichuris Vulpis

Natural and synthetic naphthoquinones as potential anti-infective agents

2021 ◽  
Vol 21 ◽  
Author(s):  
Eyra Ortiz-Pérez ◽  
Karina Vázquez ◽  
Gildardo Rivera ◽  
Cristian O. Salas ◽  
J. José Zarate-Ramos ◽  
...  
Keyword(s):  
Biological Activity ◽  
Biological Effects ◽  
Plasmodium Falciparum Malaria ◽  
Toxocara Canis ◽  
Chemotherapeutic Agents ◽  
Parasitic Diseases ◽  
Antiprotozoal Activity ◽  
Wide Range ◽  
Leishmania Spp ◽  
Natural And Synthetic

Background: Naphthoquinones are a class of aromatic compounds relevant for their chemical characteristics, structural properties, and biological activity. These compounds are found in nature with a wide range of effects, highlighting their antibacterial, antifungal, and antiprotozoal properties. Additionally, naphthoquinones are used as a scaffold to obtain new derivatives with pharmacological potential, mainly compounds against parasitic diseases. Objective: The purpose of this work was to carry out a comprehensive review of naphthoquinones and their derivatives obtained from both natural and synthetic sources, also, to well as analyze their biological activity against Leishmania spp (Leishmaniasis), Trypanosoma cruzi (Chagas disease), Plasmodium falciparum (Malaria), Toxoplasma gondii (Toxoplasmosis), and Toxocara canis (Toxocariasis). All of these agents are responsible for relevant diseases worldwide. Results : Natural naphthoquinones, such as plumbagin, diospyrin, burmanin, lapachol, lawsone and psychorubrin, show an antiprotozoal activity similar or enhanced antiprotozoal activity to reference drugs. Some naphthoquinones obtained by synthesis or semi-synthesis shown better biological activity or less toxic effects than natural compounds. Conclusion: In this review, natural and synthetic naphthoquinone showed antiparasitic activity, in the most cases with improved results than current drugs currently used in clinical trials. A modification of their structure with different functional groups can enhance their biological effects, improve solubility, and reduce undesirable side effects. Therefore, naphthoquinones are important molecules in the development of new chemotherapeutic agents against parasitic diseases.

scholarly journals Taenia hydatigena cysticercosis in wild boar (Sus scrofa) from southern Italy: an epidemiological and molecular survey

Parasitology ◽  
2020 ◽  
Vol 147 (14) ◽  
pp. 1636-1642 ◽  
Author(s):  
Giovanni Sgroi ◽  
Antonio Varcasia ◽  
Nicola D'Alessio ◽  
Paolo Varuzza ◽  
Francesco Buono ◽  
...  
Keyword(s):  
Wild Boar ◽  
Southern Italy ◽  
Parasitic Infection ◽  
Domestic Animals ◽  
Parasitic Diseases ◽  
Wild Boar Population ◽  
Domestic Life ◽  
Taenia Hydatigena ◽  
Wildlife Species ◽  
Hunting Dogs

AbstractTaenia hydatigena cysticercosis is a widespread parasitic disease of wild and domestic animals. In Europe, the increase in wild boar population may potentially contribute to the spread of this parasitic infection. To determine the occurrence of cysticerci (metacestodes) in wild boar population from southern Italy, carcasses were inspected during three hunting seasons (2016–2018). Out of 3363 wild boar examined, 229 (6.8%) harboured cysticerci with 188 (82.1%) infected by a single cyst, vs 41 (17.9%) boars having more than one. Most of the positive animals (187; 81.7%) showed cysts on the liver, whereas a multiple localization of cysticerci was reported in 10 (4.4%) wild boar. The total number of cysts retrieved from positive animals was 301 (average 1.3). Molecular analysis revealed the occurrence of a common haplotype (Hap 8) shared between wild boar and domestic animals. Our findings suggest the presence of a T. hydatigena semi-domestic life cycle in which wild boar may play an important role, due to a large number of offal available to hunting dogs, wolves and foxes during hunting seasons. Hunters may be players in the management of wildlife species to control and prevent the circulation of parasitic diseases.

An epidemiological survey of Echinococcus granulosus and other helminths in animal populations in northern Israel

1998 ◽  
Vol 72 (2) ◽  
pp. 127-132 ◽  
Author(s):  
G. Hoida ◽  
Z. Greenberg ◽  
M. Furth ◽  
Y. Malsha ◽  
P.S. Craig ◽  
...  
Keyword(s):  
Echinococcus Granulosus ◽  
Toxocara Canis ◽  
Epidemiological Survey ◽  
Intestinal Helminth ◽  
Mixed Infections ◽  
Helminth Parasites ◽  
Taenia Hydatigena ◽  
Dipylidium Caninum ◽  
Helminth Infections ◽  
Animal Populations

AbstractIn a survey carried out during the period May 1995 to November 1996, in communities of various ethnic groups in northern Israel, 206 dogs were examined for Echinococcus granulosus and other intestinal helminth parasites by arecoline hydrobromide purges and the coproantigen-ELISA. The arecoline test was performed close to the owners' homes, using plastic sheets secured to the ground. From 56 dogs examined in the Muslim town of Tamra, six (10.7%) were found to be infected with E. granulosus. Four of them also had a mixed infection of Taenia hydatigena and Dipylidium caninum (two dogs), and the remaining two dogs were infected with either D. caninum or Taenia pisiformis. An additional 18 dogs were infected with either T. pisiformis (eight dogs), D. caninum (seven dogs), or T. hydatigena (three dogs). Two of these dogs harboured mixed infections whereas the remaining 32 dogs were free of helminths. In the Jewish villages, none of the 150 dogs examined were infected with E. granulosus, although 26 (17.3%) were infected with D. caninum, four (2.7%) with Ancylostoma spp. and one (0.7%) with Toxocara canis. Only one of the 22 stray dogs and none of the 15 jackals examined were infected with E. granulosus. However, 21 (95.4%) of the dogs and 12 (80%) of the jackals harboured helminth infections, including: D. caninum (16 dogs and seven jackals), Ancylostoma spp. (five jackals), T. hydatigena (three dogs), and T. canis (one dog). Approximately 18% of the dogs and 33% of the jackals showed mixed infections with two or more of the above helminths. In the abattoirs, 52 (5.9%) of the 874 sheep and 33 (5.3%) of the 616 goats from 17 herds slaughtered in the Muslim and Druze villages were found to be infected with E. granulosus, compared with a 0% infection rate observed in 93 sheep from two herds in Jewish villages.

scholarly journals Riesgo potencial de parásitos zoonóticos presentes en heces caninas en Puerto Escondido, Oaxaca

2014 ◽  
Vol 56 (6) ◽  
pp. 625 ◽  
Author(s):  
León Vélez-Hernández ◽  
Karen Lizbeth Reyes-Barrera ◽  
Daniela Rojas-Almaráz ◽  
Mónica Alicia Calderón-Oropeza ◽  
Julieta Karina Cruz-Vázquez ◽  
...  
Keyword(s):  
Toxocara Canis ◽  
Ancylostoma Caninum ◽  
Dipylidium Caninum

Objetivo. Estimar la prevalencia de parásitos potencialmente zoonóticos en heces caninas de Puerto Escondido. Material y métodos. La ciudad se dividió en diez zonas de estudio y éstas se categorizaron en hábitats natural, urbano y suburbano. Se colectaron muestras fecales caninas del piso. Se recuperaron los parásitos por medio de técnicas coproparasitológicas de flotación y frotis directo para su observación microscópica y posterior identificación. Se estimó la prevalencia parasitaria en las heces caninas. Resultados. Todas las zonas presentaron fecalismo canino. La prevalencia parasitaria fue de 73.33%. Los parásitos con mayor prevalencia fueron Toxocara canis (47.78%), Ancylostoma caninum (17.88%) y Dipylidium caninum (13.89%). Conclusión. El fecalismo canino proviene de perros errantes y con dueño. Del total de parásitos encontrados, 66.66% son zoonóticos. Los factores que favorecen la problemática son el hábitat suburbano, el manejo indeseable de la basura y la tenencia irresponsable de los cánidos.

scholarly journals Parasites gastro-intestinaux chez les chiens à Lubumbashi

2019 ◽  
Vol 71 (4) ◽  
pp. 173
Author(s):  
Daudet Byakya ◽  
Boniface Lombe ◽  
Yan Madimba ◽  
Emmanuel Kaluendi
Keyword(s):  
Toxocara Canis ◽  
Dipylidium Caninum ◽  
République Démocratique Du Congo ◽  
Toxascaris Leonina

Une étude parasitologique a été menée en 2015 sur des chiens de sexe, âge et race différents, vivant en liberté dans la ville de Lubumbashi, République démocratique du Congo. Des échantillons de fèces ont été prélevés et analysés par coproscopie selon une méthode de flottation. Sur les 120 chiens examinés, 78 (65 %) étaient infestés, parmi lesquels 74 (61,7 %) avaient des helminthes gastro-intestinaux et 4 (3,3 %) avaient des coccidies. Les coproscopies ont révélé la présence de cinq espèces de parasites : Ankylostoma spp. (41 chiens), Toxocara canis (22), Toxascaris leonina (8), Isospora canis (4) et Dipylidium caninum (3). I. canis n’a été retrouvé que chez les chiots. Le dépistage fréquent d’ankylostomes et de T. canis suggère qu’il existe à Lubumbashi un risque de contamination de l’homme par ces parasites zoonotiques.

scholarly journals Toxocara Seroprevalence and Risk Factor Analysis in Four Communities of the Wiwa, an Indigenous Tribe in Colombia

2021 ◽  
Vol 9 (8) ◽  
pp. 1768
Author(s):  
Patrick Waindok ◽  
Simone Kann ◽  
Andrés Aristizabal ◽  
Juan Carlos Dib ◽  
Christina Strube
Keyword(s):  
Factor Analysis ◽  
Risk Factor ◽  
Food Source ◽  
Age Groups ◽  
Toxocara Canis ◽  
Domestic Animals ◽  
Toxocara Cati ◽  
Serum Samples ◽  
Seropositivity Rate ◽  
Clean Drinking Water

The life of the indigenous Wiwa tribe in northeast Colombia is characterized by lacking access to clean drinking water and sanitary installations. Furthermore, free-roaming domestic animals and use of yucca and/or manioc as a primary food source favor the transmission of soil-transmitted helminths, e.g., Toxocara canis and Toxocara cati, the roundworms of dogs and cats. Infection may result in the clinical picture of toxocarosis, one of the most common zoonotic helminthoses worldwide. To estimate the Toxocara seroprevalence in four different villages of the Wiwa community, serum samples from 483 inhabitants were analyzed for anti-Toxocara-antibodies. Overall, 79.3% (383/483) of analyzed samples were seropositive. Statistically significant differences were observed between the four villages, as well as age groups (adults > adolescents > children), while sex had no effect. The high seropositivity rate demonstrates the risk of zoonotic roundworm infections and potential clinical disease in vulnerable indigenous inhabitants.

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