Investigation of the relationship between farrowing environment, sex steroid concentrations and maternal aggression in gilts

1998 ◽  
Vol 50 (1-2) ◽  
pp. 95-109 ◽  
Author(s):  
K.A McLean ◽  
A.B Lawrence ◽  
J.C Petherick ◽  
L Deans ◽  
J Chirnside ◽  
...  
Keyword(s):  
Sex Steroid ◽  
Maternal Aggression ◽  
The Relationship

Investigation of the relationship between farrowing environment, sex steroid concentrations and maternal aggression in gilts

1996 ◽  
Vol 1996 ◽  
pp. 34-34
Author(s):  
K.A. McLean ◽  
A.B. Lawrence ◽  
J.C. Petherick ◽  
L. Deans ◽  
J. Chirnside ◽  
...  
Keyword(s):  
Sex Steroids ◽  
Maternal Care ◽  
Social Behaviour ◽  
Social Rank ◽  
Sex Steroid ◽  
Maternal Behaviour ◽  
Maternal Aggression ◽  
The Relationship

Maternal oestrogen and progesterone have been shown to be important in the initiation of maternal behaviour (e.g. Shipka and Ford, 1991). It has also been suggested by Csermely and Nicosia (1991) that there is an association between social rank and the performance of maternal behaviour. This study investigated the relationships between social behaviour during pregnancy, levels of sex steroids around parturition and the level of maternal care shown by gilts. Sows and gilts are generally housed in farrowing crates during parturition and lactation. This study also ascertained whether or not the farrowing environment affected sex steroid concentrations.

Investigation of the relationship between farrowing environment, sex steroid concentrations and maternal aggression in gilts

1996 ◽  
Vol 1996 ◽  
pp. 34-34
Author(s):  
K.A. McLean ◽  
A.B. Lawrence ◽  
J.C. Petherick ◽  
L. Deans ◽  
J. Chirnside ◽  
...  
Keyword(s):  
Sex Steroids ◽  
Maternal Care ◽  
Social Behaviour ◽  
Social Rank ◽  
Sex Steroid ◽  
Maternal Behaviour ◽  
Maternal Aggression ◽  
The Relationship

Maternal oestrogen and progesterone have been shown to be important in the initiation of maternal behaviour (e.g. Shipka and Ford, 1991). It has also been suggested by Csermely and Nicosia (1991) that there is an association between social rank and the performance of maternal behaviour. This study investigated the relationships between social behaviour during pregnancy, levels of sex steroids around parturition and the level of maternal care shown by gilts. Sows and gilts are generally housed in farrowing crates during parturition and lactation. This study also ascertained whether or not the farrowing environment affected sex steroid concentrations.

Sex steroids-induced neurogenesis in adult brain: a better look at mechanisms and mediators

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Hamideh Abotalebi ◽  
Babak Ebrahimi ◽  
Raziyeh Shahriyari ◽  
Reyhaneh Shafieian
Keyword(s):  
Sex Steroids ◽  
Ventricular Zone ◽  
Mammalian Species ◽  
Adult Brain ◽  
Sex Steroid ◽  
Subgranular Zone ◽  
Human Beings ◽  
The Relationship ◽  
The Brain

Abstract Adult neurogenesis is the production of new nerve cells in the adult brain. Neurogenesis is a clear example of the neuroplasticity phenomenon which can be observed in most of mammalian species, including human beings. This phenomenon occurs, at least, in two regions of the brain: the subgranular zone of the dentate gyrus in hippocampus and the ventricular zone of lateral ventricles. Numerous studies have investigated the relationship between sex steroid hormones and neurogenesis of adult brain; of which, mostly concentrated on the role of estradiol. It has been shown that estrogen plays a significant role in this process through both classic and non-classic mechanisms, including a variety of different growth factors. Therefore, the objective of this review is to investigate the role of female sex steroids with an emphasis on estradiol and also its potential implications for regulating the neurogenesis in the adult brain.

scholarly journals The Impact of Reversible Gonadal Sex Steroid Suppression on Serum Leptin Concentrations in Children with Central Precocious Puberty1

1998 ◽  
Vol 83 (4) ◽  
pp. 1091-1096
Author(s):  
Mark R. Palmert ◽  
Sally Radovick ◽  
Paul A. Boepple
Keyword(s):  
Body Composition ◽  
Longitudinal Study ◽  
Sex Steroids ◽  
Central Precocious Puberty ◽  
Sex Steroid ◽  
Serum Leptin ◽  
Reproductive Axis ◽  
Discernible Effect ◽  
The Impact ◽  
The Relationship

Serum leptin concentrations increase during childhood in both sexes. During sexual maturation, levels rise further in girls, but decrease in boys. These data suggest that testosterone either directly suppresses leptin levels or induces changes in body composition that result in lower leptin concentrations. To examine further the relationship between sex steroids and leptin, we performed a longitudinal study in children with central precocious puberty (28 girls and 12 boys) before, during, and after discontinuation of GnRH agonist-induced pituitary-gonadal suppression. Nighttime and daytime leptin levels were measured to determine whether the activity of the pituitary-gonadal axis affects their diurnal variation. In the boys, suppression of testosterone increased leptin levels, whereas resumption of puberty was associated with decreased leptin levels [3.5 ± 0.8 vs. 9.5 ± 3.1 ng/dL (P = 0.005) and 12.2 ± 4.5 vs. 7.0 ± 2.6 ng/dL (P = 0.012), respectively]. Serum leptin levels did not change in the girls with alteration of the pituitary-ovarian axis and consistently exceeded those in boys. Nighttime levels were consistently greater than daytime values by an average of 38.3% in the girls and 29.4% in the boys. These serial observations during reversible pituitary-gonadal suppression suggest that testosterone decreases leptin concentrations, but that estrogen, at least in this childhood model, has no discernible effect. In addition, our data indicate that the presence of the diurnal rhythm in leptin concentrations is independent of the state of the reproductive axis.

scholarly journals Sex Steroid Hormones and Cell Dynamics in the Periodontium

1994 ◽  
Vol 5 (1) ◽  
pp. 27-53 ◽  
Author(s):  
Angelo Mariotti
Keyword(s):  
Steroid Hormones ◽  
Hormone Receptors ◽  
Contraceptive Use ◽  
Sex Steroid Hormones ◽  
Sex Steroid ◽  
Cell Dynamics ◽  
Periodontal Tissues ◽  
Oral Contraceptive Use ◽  
Clinical Observations ◽  
The Relationship

The biological changes that occur in tissues of the periodontium during puberty, the menstrual cycle, pregnancy, menopause, and oral contraceptive use have heightened interest in the relationship between sex steroid hormones and periodontal health. These clinical observations coupled with tissue specificity of hormone localization, identification of hormone receptors, as well as the metabolism of hormones have strongly suggested that periodontal tissues are targets for androgens, estrogens, and progestins. The etiologies of periodontal endocrinopathies are diverse; nonetheless, periodontal pathologies may be a consequence of the actions and interactions of sex steroid hormones on specific cells found in the periodontium.

scholarly journals The Nexus of Endocrine Signaling and Cancer: How Steroid Hormones Influence Genomic Stability

Endocrinology ◽  
2020 ◽  
Vol 162 (1) ◽  
Author(s):  
Shinjini Ganguly ◽  
Divya Naik ◽  
Andrew Muskara ◽  
Omar Y Mian
Keyword(s):  
Dna Damage ◽  
Steroid Hormones ◽  
Dna Damage Response ◽  
Steroid Hormone ◽  
Genomic Stability ◽  
Genotoxic Stress ◽  
Steroid Hormone Receptors ◽  
Sex Steroid ◽  
Damage Response ◽  
The Relationship

Abstract Endocrine-driven malignancies, including breast and prostate cancer, are among the most common human cancers. The relationship between sex steroid hormones (eg, androgen, estrogen, and progesterone), their cognate receptors, and genomic stability lie at the center of endocrine-driven cancer development, progression, and therapeutic resistance. A variety of direct and indirect mechanisms have been described that link steroid hormone signaling to the loss of genomic integrity that drives early carcinogenesis. These effects are often enriched within endocrine receptor cistromes, accounting for the high proportion of mutations and rearrangements in the region of hormone response elements. In other cases, the effects are generalized and rely on a complex array of genetic, epigenetic, and metabolic interactions. Both androgen and estrogen receptors directly modulate the DNA damage response by trans-activating DNA damage response genes and redirecting the cellular repair machinery in the wake of genotoxic stress. Here we review the key mechanistic underpinnings of the relationship between sex steroid hormone receptors and genomic stability. In addition, we summarize emerging research in this area and discuss important implications for cancer prevention and treatment.

scholarly journals Sex steroids in the tumor microenvironment and prostate cancer progression

2018 ◽  
Vol 25 (3) ◽  
pp. R179-R196 ◽  
Author(s):  
Clovis Boibessot ◽  
Paul Toren
Keyword(s):  
Prostate Cancer ◽  
Tumor Microenvironment ◽  
Cancer Progression ◽  
Sex Steroids ◽  
Biological Effects ◽  
Basic Research ◽  
Prostate Tumor ◽  
Sex Steroid ◽  
Prostate Cancer Progression ◽  
The Relationship

Prostate cancer is uniquely dependent on androgens. Despite years of research on the relationship between androgens and prostate cancer, many questions remain as to the biological effects of androgens and other sex steroids during prostate cancer progression. This article reviews the clinical and basic research on the influence of sex steroids such as androgens, estrogens and progesterone within the prostate tumor microenvironment on the progression of prostate cancer. We review clinical studies to date evaluating serum sex steroids as prognostic biomarkers and discuss their respective biological effects within the prostate tumor microenvironment. We also review the link between genomic alterations and sex steroid levels within prostate tumors. Finally, we highlight the links between sex steroid levels and the function of the immune system within the tumor microenvironment. As the context of treatment of lethal prostate cancer evolves over time, an understanding of this underlying biology remains central to developing optimal treatment approaches.

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