scholarly journals Clinical Characteristics and Angiographic Profile of Acute Coronary Syndrome Patients in a Tertiary Hospital of Bangladesh

2018 ◽  
Vol 33 (1) ◽  
pp. 10-15
Author(s):  
Mohsin Ahmed ◽  
Khandaker Abu Rubaiyat ◽  
Mohammed Abaye Deen Saleh ◽  
Abdul Wadud Chowdhury ◽  
CM Khudrate E Khuda ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Healthy Person ◽  
Diabetic Patients ◽  
College Hospital ◽  
Coronary Syndrome ◽  
Triple Vessel Disease ◽  
Artery Disease

Aims: Coronary artery disease is a devastating disease precisely because an otherwise healthy person in the prime of life may die or become disabled without warning. The objectives were to study the clinical profile, risk factors prevalence, angiographic distribution and severity of coronary artery stenosis in acute coronary syndrome (ACS) patients admitted in Cardiology Department of Dhaka Medical College Hospital, Dhaka.Materials and Methods: A total of 800 patients of ACS were analyzed for various risk factors, angiographic patterns and severity of coronary artery disease at DMCH, Dhaka, Bangladesh.Results: Mean age of presentation was 51.27±8.80 years. Majority were male 628 (78.5%) and rest were females (21.5%). Most patients had ST elevated myocardial infarction (STEMI) 509 (63.6%) followed by non-STEMI (NSTEMI) 207 (25.9%) and Unstable Angina (UA) 84 (10.5%). Risk factors: smoking was present in 388 (48.5%), hypertension in 289 (36.13%), diabetes in 235 (29.38%), dyslipidaemia in 169 (21.13%) and obesity in 356 (44.5%) patients. Singlevessel disease was present in 30.32% patients, Doublevessel disease was present in 23.23% patients and Triple vessel disease was present in 27.15% patients.Conclusion: STEMI was the most common presentation. ACS occurred earlier in comparison to Western population. Smoking was most prevalent risk factor. Diabetic patients had more multivessel disease.Bangladesh Heart Journal 2018; 33(1) : 10-15

scholarly journals Relationship between the Severity of Coronary Artery Disease and Cardiovascular Risk Factors in Acute Coronary Syndrome: Based on Tehran Heart Center’s Data Registry

2021 ◽  
Author(s):  
Negar Omidi ◽  
Saeed Sadeghian ◽  
Mojtaba Salarifar ◽  
Arash Jalali ◽  
Seyed Hesameddin Abbasi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Family History ◽  
Gensini Score ◽  
Coronary Syndrome ◽  
Artery Disease

Background: Acute coronary syndrome (ACS) is one of the main causes of mortality worldwide. We sought to evaluate the correlation between the severity of coronary artery disease (CAD) and conventional coronary artery risk factors in a large cohort of patients with ACS. Methods: This study included all patients admitted to the coronary care unit with a diagnosis of ACS between 2003 and 2017. The patients were divided into 2 groups: 1) unstable angina and 2) myocardial infarction. The aims of this study were to evaluate the effects of the risk factors and extension of coronary artery stenosis in patients with ACS according to the Gensini score. Results: Of a total 40 319 patients who presented with ACS, 18 862 patients (mean age =60.4±11.14 y, male: 67.2%) underwent conventional coronary angiography and met our criteria to enter the final analysis. The median of the Gensini score was 50 (25–88) in the study population. The multivariable analysis showed that age, sex, diabetes mellitus, hypertension, dyslipidemia, family history, cigarette smoking, opium consumption, and myocardial infarction increased the risk of positive Gensini scores. All the aforementioned risk factors, except cigarette smoking and opium consumption, increased the severity of stenosis in those with positive Gensini scores. The strongest relationship was seen vis-à-vis myocardial infarction, sex, and diabetes mellitus. Conclusion: Our findings suggest that age, sex, diabetes mellitus, dyslipidemia, hypertension, family history, and myocardial infarction have significant effects on the severity of CAD. The obesity paradox in relation to CAD should be taken into consideration and needs further investigation in patients with ACS.

scholarly journals Caronary Artery Disease in Women

2014 ◽  
Vol 15 (2) ◽  
pp. 135-140
Author(s):  
NS Neki
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Cardiovascular Disease ◽  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Coronary Disease ◽  
Coronary Syndrome ◽  
Artery Disease ◽  
Prevalent Form

Coronary artery disease (CAD) - which includes coronary atherosclerotic disease, myocardial infarction (MI), acute coronary syndrome and angina - is the most prevalent form of cardiovascular disease and is the largest subset of this mortality. Coronary artery disease (CAD) is a leading cause of death of women and men  worldwide. CAD’s impact on women traditionally has been underappreciated due to higher rates at younger ages in men. Microvascular coronary disease disproportionately affects women. Women have unique risk factors for CAD, including those related to pregnancy and autoimmune disease.DOI: http://dx.doi.org/10.3329/jom.v15i2.20687 J MEDICINE 2014; 15 : 135-140

Risk factors for coronary artery disease and acute coronary syndrome in patients ≤40 years old

2016 ◽  
Vol 12 (5) ◽  
pp. 545-552 ◽  
Author(s):  
Hassan Alkhawam ◽  
Robert Sogomonian ◽  
Mohammed El-Hunjul ◽  
Mohamad Kabach ◽  
Umer Syed ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Coronary Syndrome ◽  
Artery Disease

scholarly journals Level of Knowledge About Coronary Artery Disease is Poor Among Bangladeshi Hospitalized Patient Following Acute Coronary Syndrome

2014 ◽  
Vol 14 (2) ◽  
pp. 119-122
Author(s):  
Md. Motlabur Rahman ◽  
M.A. Sattar Sarker ◽  
Tania Mahbub ◽  
Shahana Khanam ◽  
Nahida Zafrin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Coronary Disease ◽  
Risk Of Death ◽  
Coronary Syndrome ◽  
Level Of Knowledge ◽  
Hospitalized Patient ◽  
Artery Disease

Back ground: Coronary artery disease (CAD) is a major risk of death worldwide. Level of education about this important health problem is poor in our general population. Aims of this study was to find out simple knowledge about coronary disease, and to find the knowledge about risk factors, symptoms, complications and knowledge about prevention of coronary disease among the hospitalized patient who admitted to SSMS and Mitford Hospital and diagnosed as patients of Acute Coronary Syndrome (ACS).Method: A pre tested questionnaire regarding assessment of level of knowledge about CAD was used to studied of the patients was admitted to SSMC and Mitford Hospital with the diagnosis of acute coronary syndrome during the period April 2009 to October 2009.Result: Our study suggests that there is a lack of awareness among a sampled Bangladeshi population regarding CAD and its modifiable risk factors. We found that the low level of knowledge in the majority of patients, the rural and less educated patients had a lower level of knowledge.Conclusion: Our cardiac patients have poor knowledge regarding their disease; improvement of knowledge is needed through much education to prevent CAD.DOI: http://dx.doi.org/10.3329/jom.v14i2.19639 J Medicine 2013, 14(2): 119-122

scholarly journals Profile of acute coronary syndrome in young diabetics: a review

2020 ◽  
Vol 7 (5) ◽  
pp. 869
Author(s):  
Lakshmi Narayanan ◽  
Mohamed Hanifah
Keyword(s):  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Clinical Presentation ◽  
Exclusion Criterion ◽  
Diabetic Patients ◽  
Angiographic Finding ◽  
Coronary Syndrome ◽  
Vessel Disease ◽  
Artery Disease

The clinical presentation and angiographic findings of coronary artery disease (CAD) varies from diabetic and non-diabetic patients and varies with the age of presentation. Coronary artery disease in patients below the age of 45 is a special subset. The objective of this study is to compare the clinical and angiographic profile in patients with the acute coronary syndrome (ACS) with diabetes mellitus (DM) and without DM below the age of 45 years. Clinical Presentation of coronary artery disease in young patients with various risk factors differs, which plays an important role in management strategies. This was conducted through internet search on PubMed and ProQuest database from 2000 to until 2019. Key words used for searching are acute coronary syndrome, young diabetics, and clinical, angiographic profile. An important exclusion criterion is studies which included type one diabetic patients. Totally 35 papers were reviewed. Pattern of involvement of coronary arteries as assessed by the coronary angiographic study is found to be different in younger CAD patients. Atypical clinical presentation and distinct angiographic finding are common in diabetics below the age of 45. In most of the studies single vessel disease (SVD) is the most common angiographic finding in young CAD and non-diabetics. While the diabetics showed the more diffuse pattern of double vessel disease (DVD).

scholarly journals Distribution of Risk Factors in Patients with Acute Coronary Syndrome – a Hospital Based Study

2003 ◽  
Vol 42 (148) ◽  
Author(s):  
Man B KC ◽  
S Rajbhandari ◽  
D Sharma ◽  
R Malla ◽  
YR Limbu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Disease Risk ◽  
Positive Family History ◽  
Modifiable Risk Factors ◽  
Coronary Syndrome ◽  
Strong Trend ◽  
Artery Disease

A total of 230 patients admitted in coronary care unit of Shahid Gangalal National Heart Centre in betweenNovember 2001 and October 2002 were studied. 157 (68.2%) were male, with mean age of 62.8±11.8 years.Majority of acute coronary syndrome (ACS) events were observed in males with advanced age (> 65 years).About 68% patients with ACS were smoker, the most common modifiable risk factor followed by hypertension,dyslipidaemia and diabetes. A strong trend towards development of coronary artery disease (CAD) wasfound in subjects with positive family history of CAD. Multiple risk factors (2 or more) were present in vastmajority of patients. Modifiable risk factors, with smoking at number one position are more common inacute coronary syndrome patients. Appropriate management of modifiable risk factors is advisable to reducethe incidence of coronary artery disease.Key Words: Coronary Artery Disease, Risk Factors.

scholarly journals Evaluation of Platelet Parameters in Patients With Coronary Artery Disease

2020 ◽  
Author(s):  
Mahdieh Mehrpouri1 ◽  
Afshin Ahmad Pour ◽  
Esmail Shahabi Satlsar
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Coronary Angiography ◽  
Healthy Volunteers ◽  
Ecg Changes ◽  
Coronary Syndrome ◽  
Significant Difference ◽  
Artery Disease

Coronary artery disease (CAD) is one of the leading causes of death worldwide; therefore, identifying new risk factors to predict the severity of the disease is thought to be associated with mortality reduction. In an effort to investigate whether platelet parameters are related to the extent of CAD and can be considered as risk factors, we designed experiments to evaluate platelet parameters in these patients. In a cross‐sectional study, sixty-nine patients with CAD (including fifty-two patients with acute coronary syndrome and seventeen patients with stable angina) and sixty-four healthy volunteers were evaluated for platelet count, mean platelet volume (MPV), and platelet distribution width (PDW). Echocardiography, electrocardiogram (ECG), and coronary angiography were conducted as well. Results showed significantly higher values for MPV and PDW in patients with acute coronary syndrome as compared to patients with stable angina and healthy volunteers (P<0.001 and P=0.009, respectively). There was no significant difference in platelet count between patients and healthy volunteers (P=0.379). Our results also revealed a significant difference in the ejection fraction (EF) percentage between the three groups (P=0.008). Investigating the correlation between platelet parameters and EF percentage, ECG changes, and the results of coronary angiography did not show any significant association. The present study showed that the elevated levels of MPV and PDW in patients with CAD are not related to the extent of coronary artery disease, which was estimated by echocardiography, ECG changes, and coronary angiography. Thus, these parameters cannot be considered as risk factors for coronary artery disease.

scholarly journals Clinical Profile of Acute Coronary Syndrome

2021 ◽  
pp. 259-262
Author(s):  
Azeem Ahamed ◽  
N. Deepthi
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Tobacco Use ◽  
Metabolic Disorders ◽  
Clinical History ◽  
Clinical Profile ◽  
Coronary Syndrome ◽  
Artery Disease

Background: In the developing world, coronary artery disease (CAD) is considered to be a leading source of illness and ultimately death. Indians are nowadays linked to a more dangerous variant of coronary artery disease (CAD) with a lower age of onset and is more common in men. Aim: To analyse the clinical profile of patients with ACS syndrome for the purpose of drawing predominance in demography, metabolic disorders and tobacco use. Materials and Methods: We enrolled 50 patients with characteristic ECG alterations and clinical history who were admitted to the emergency department between January and August 2021 in a prospective research at Saveetha Medical College and Hospital. Every patient had a predetermined Performa filled out, which included a full clinical history and investigation procedures. The clinical history disclosed details regarding the patient's age, gender, and risk factors. Results: On analysis, results were conclusive of male predominance probably accentuated by tobacco use, alcohol consumption and other metabolic disorders. Conclusion: With prevalence of risk factors on rise, younger individuals are also affected. Proper risk factor management will help in preventing Acute coronary syndrome.

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