MRI signal changes in the white matter after corpus callosotomy

1999 ◽  
Vol 21 (4) ◽  
pp. 691-695 ◽  
Author(s):  
Divya S Khurana ◽  
Richard H Strawsburg ◽  
Richard L Robertson ◽  
Joseph R Madsen ◽  
Sandra L Helmers
Keyword(s):  
White Matter ◽  
Corpus Callosotomy ◽  
Signal Changes

Clinical and Neuroimaging Changes of Subacute Sclerosing Panencephalitis – Experience 30 Cases in Tertiary Care Center in Bangladesh

2021 ◽  
Vol 2 (3) ◽  
pp. 1-4
Author(s):  
Gopen Kumar Kundu ◽  
Mohammad Monir Hossain
Keyword(s):  
Early Childhood ◽  
White Matter ◽  
Subacute Sclerosing Panencephalitis ◽  
Tertiary Care ◽  
Stage Ii ◽  
Cortical Atrophy ◽  
Periventricular White Matter ◽  
History Of ◽  
Signal Changes ◽  
Intense Signal

Background: Subacute sclersing panencephalitis (SSPE) is a very rare progressive, fatal neurodegenerative disease of the control nervous system of childhood and early adolescence. It is a slow virus disease caused by persistent defective measles virus infection of the brain Objective: To see the clinical andneuro-imaging findings in children with Subacute sclerosing panencephalitis. Methods: This retrospective study was conducted at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, a tertiary care premier Postgraduate Medical Institution in Bangladesh. Thirty (30) Subacute sclerosing panencephalitis (SSPE) children were evaluated at paediatric neurology ward during the period January 2010 to December 2017. Diagnosis was based on typical clinical characteristic features, the presence of periodic discharges on EEG, demonstration of raised antibody titer against measles in the plasma and cerebrospinal fluid Detected by ELISA in all patients. Results: Total number of studied children were 30. Mean age was 10.2±3.1 year and Male female ratio was 5:1. Most of the patient arrived from poor socio-economic (83.33%) background of rural area (66.67%) of Bangladesh. Among them 46.67% had history of measles infection during early childhood. Progressive deterioration of school performance (50%), gait disturbance (70%), myoclonus (83%) dysarthria (43%) and Ocular manifestations like optic atrophy & papilledema (83.33%) were the main presenting feature of our studied children. All of the patients (100%) showed positive measles specific antibody IgG in CSF and On electroencephalographic findings showed periodic burst suppression in 90.90% cases. Most of the children (56.6%) were in stage II category and other 3.3%, 33.3%,6.6%, were stage I, stage III, stage IV category respectively. Neuroimaging study showed abnormalities in 45.83% cases included periventricular white matter hyper intense signal changes, cortical atrophy and ischaemic change. Conclusion: In our study most of the SSPE patient were in stage II.About half of the patient had history of measles infection during early childhood. Neuroimaging abnormalities found in about half of the cases and majority cases were in stage II. Common neuroimaging abnormalities were periventricular white matter hyper intense signal changes and cortical atrophy.

scholarly journals Bilateral Telencephalic Gliomatosis Cerebri in a Dog

2014 ◽  
Vol 2014 ◽  
pp. 1-5
Author(s):  
Mario Ricciardi ◽  
Antonio De Simone ◽  
Pasquale Giannuzzi ◽  
Maria Teresa Mandara ◽  
Alice Reginato ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
White Matter ◽  
Mass Effect ◽  
Gliomatosis Cerebri ◽  
Imaging Findings ◽  
Mri Findings ◽  
Intact Male ◽  
Presumptive Diagnosis ◽  
Atypical Cells ◽  
Signal Changes

An 8-year-old intact male Lagotto Romagnolo was presented with forebrain signs. Neuroanatomic localization was diffuse prosencephalon. MRI revealed diffuse, bilateral, and symmetric T2 and FLAIR hyperintensities in the parieto-occipital white matter and corpus callosum. No mass effect or contrast enhancement was noted. Analysis of cerebrospinal fluid revealed normal protein content and mild mononuclear pleocytosis. Atypical cells were not identified. 15 days later because of the worsening of clinical condition the patient was euthanized upon owner’s request. Neuropathological investigations were consistent with gliomatosis cerebri (GC). Such an unusual imaging pattern appeared similar to some cases of human GC and to a previous reported case in a dog, suggesting a possible repeatable imaging findings for this rare brain neoplasm. GC should be included in the MRI differentials for diffuse bilateral white matter signal changes and specific MRI findings described in this report may help in reaching a presumptive diagnosis of this tumor.

scholarly journals Symptomatic Bilateral Xanthogranuloma of the Choroid Plexus

2017 ◽  
Vol 08 (S 01) ◽  
pp. S123-S126 ◽  
Author(s):  
Selin Tural Emon ◽  
Erek Ozturk ◽  
Kaan Meric ◽  
Fugen Aker ◽  
Metin Orakdogen
Keyword(s):  
White Matter ◽  
Choroid Plexus ◽  
Brain Edema ◽  
Ventricular Dilatation ◽  
Benign Lesions ◽  
Additional Information ◽  
Signal Changes ◽  
Enhanced Imaging

ABSTRACTXanthogranulomas (XGRs) of the choroid plexus are rare, asymptomatic, and benign lesions usually found incidentally. Here, we present a case of a 47-year-old male with bilateral XGR of the choroid plexus with periventricular edema and discuss our case in relation to a review of existing literature pertaining to the radiology of XGRs. To the best of our knowledge, this is the first reported case of bilateral trigonal XGR causing brain edema without ventricular dilatation. Despite the fact that they can cause hydrocephalus, XGRs are silent and benign lesions. Although the etiopathology of XGRs remains poorly understood, enhanced imaging analyses may provide additional information regarding edema and focal white matter signal changes.

Isolated mild white matter signal changes in preterm infants: a regional approach for comparison of cranial ultrasound and MRI findings

2014 ◽  
Vol 34 (6) ◽  
pp. 476-482 ◽  
Author(s):  
M Weinstein ◽  
D Ben Bashat ◽  
V Gross-Tsur ◽  
Y Leitner ◽  
I Berger ◽  
...  
Keyword(s):  
White Matter ◽  
Preterm Infants ◽  
Cranial Ultrasound ◽  
Mri Findings ◽  
Regional Approach ◽  
Signal Changes

scholarly journals Rapid Progression of White Matter Signal Changes and Frontotemporal Atrophy in Globular Glial Tauopathy

2020 ◽  
Author(s):  
Yuya Ohno ◽  
Toshimasa Ikeda ◽  
Keita Sakurai ◽  
Kentaro Yamada ◽  
Tatsuya Tomonari ◽  
...  
Keyword(s):  
White Matter ◽  
Rapid Progression ◽  
Globular Glial Tauopathy ◽  
Signal Changes

FT-IR microspectroscopic analysis of diseased white matter brain tissues

1995 ◽  
Vol 53 ◽  
pp. 968-969
Author(s):  
Steven M. Le Vine ◽  
David L. Wetzel
Keyword(s):  
White Matter ◽  
Gray Matter ◽  
Twitcher Mouse ◽  
Grid Pattern ◽  
Marked Contrast ◽  
Spatially Resolved ◽  
Ft Ir ◽  
Ir Microspectroscopy ◽  
Chemical Evidence

In situ FT-IR microspectroscopy has allowed spatially resolved interrogation of different parts of brain tissue. In previous work the spectrrscopic features of normal barin tissue were characterized. The white matter, gray matter and basal ganglia were mapped from appropriate peak area measurements from spectra obtained in a grid pattern. Bands prevalent in white matter were mostly associated with the lipid. These included 2927 and 1469 cm-1 due to CH2 as well as carbonyl at 1740 cm-1. Also 1235 and 1085 cm-1 due to phospholipid and galactocerebroside, respectively (Figs 1and2). Localized chemical changes in the white matter as a result of white matter diseases have been studied. This involved the documentation of localized chemical evidence of demyelination in shiverer mice in which the spectra of white matter lacked the marked contrast between it and gray matter exhibited in the white matter of normal mice (Fig. 3).The twitcher mouse, a model of Krabbe’s desease, was also studied. The purpose in this case was to look for a localized build-up of psychosine in the white matter caused by deficiencies in the enzyme responsible for its breakdown under normal conditions.

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