Early diagnosis of cardiac right-to-left shunts in intensive care J. Klingelh�fer, J.J. Schwarze, D. Sander, I. Wittich, B. Conrad. Department of Neurology, Technical University, Munich, Germany

1997 ◽  
Vol 5 ◽  
pp. 2-3
Keyword(s):  
Intensive Care ◽  
Early Diagnosis ◽  
Technical University

scholarly journals COVID-19: A Geriatric Emergency

Geriatrics ◽  
2020 ◽  
Vol 5 (2) ◽  
pp. 24 ◽  
Author(s):  
Virginia Boccardi ◽  
Carmelinda Ruggiero ◽  
Patrizia Mecocci
Keyword(s):  
Intensive Care ◽  
Early Diagnosis ◽  
Older Patients ◽  
Early Recognition ◽  
Health Conditions ◽  
Italian Population ◽  
Management Skills ◽  
Atypical Symptoms ◽  
Clinical Complexity ◽  
Compensatory Effort

The older Italian population is posing a challenge in the number of deaths for coronavirus disease 2019 (COVID-19). According to previous data from China, pre-existing health conditions dramatically increase the risk of dying from COVID-19. The presence of multiple diseases in older patients may be considered as a mark of frailty, which increases the person’s vulnerability to stress and impairs the multisystemic compensatory effort to restore homeostasis. The clinical complexity associated with the management of frailty may increase the risk of complications during infection as well as the lack of the early recognition of atypical symptoms. There is an urgent need to share expertise and clinical management skills with geriatricians as well as the need for early diagnosis to start treatment at the earliest convenience in the community, with the aim to avoid the collapse of intensive care units.

Innovative haematological parameters for early diagnosis of sepsis in adult patients admitted in intensive care unit

2017 ◽  
Vol 71 (4) ◽  
pp. 330-335 ◽  
Author(s):  
Sabrina Buoro ◽  
Barbara Manenti ◽  
Michela Seghezzi ◽  
Paola Dominoni ◽  
Tiziano Barbui ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Early Diagnosis ◽  
Area Under The Curve ◽  
Clinical Information ◽  
Operating Characteristics ◽  
Early Management ◽  
Reactive Protein ◽  
Icu Stay ◽  
Immature Platelet Fraction

AimsThis study was aimed to investigate the role of erythrocyte, platelet and reticulocyte (RET) parameters, measured by new haematological analyser Sysmex XN and C reactive protein (CRP), for early diagnosis of sepsis during intensive care unit (ICU) stay.MethodsThe study population consisted of 62 ICU patients, 21 of whom developed sepsis during ICU stay and 41 who did not. The performance for early diagnosing of sepsis was calculated as area under the curve (AUC) of receiver operating characteristics curves analysis.ResultsCompared with CRP (AUC 0.81), immature platelet fraction (IPF) (AUC 0.82) showed comparable efficiency for identifying the onset of sepsis. The association with the risk of developing sepsis during ICU stay was also assessed. One day before the onset of sepsis, a decreased of RET% was significantly associated with the risk of developing sepsis (OR=0.35, 95% CI 0.14 to 0.87), whereas an increased of IPF absolute value (IPF#) was significantly associated with the risk of developing sepsis (OR=1.13, 95% CI 1.03 to 1.24) 2 days before the onset of sepsis. The value of CRP was not predictive of sepsis at either time points.ConclusionsIPF# and RET% may provide valuable clinical information for predicting the risk of developing sepsis, thus allowing early management of patients before the onset of clinically evident systemic infections.

scholarly journals Neutrophil-lymphocyte ratio in the early diagnosis of sepsis in an intensive care unit: a case-control study

2019 ◽  
Vol 31 (1) ◽  
Author(s):  
Eduarda Cristina Martins ◽  
Lilian da Fe Silveira ◽  
Karin Viegas ◽  
Andrea Diez Beck ◽  
Geferson Fioravantti Júnior ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Early Diagnosis ◽  
Case Control Study ◽  
Case Control ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Control Study

scholarly journals Covid - 19 Associated Pulmonary Aspergillosis (CAPA) in Critically Ill Patients : A Case Report

2021 ◽  
Vol 10 (9) ◽  
pp. 402-406
Author(s):  
Himadri Dutta Vandana Sinha ◽  
Anup Jyoti Dutta Pinku Sarma
Keyword(s):  
Intensive Care ◽  
Case Report ◽  
Early Diagnosis ◽  
Critically Ill Patients ◽  
Private Hospital ◽  
Standard Treatment ◽  
Pulmonary Aspergillosis ◽  
The World ◽  
Different Parts

In the present study report three cases of covid-19 associated Pulmonary Aspergillosis from covid ICU of a private hospital. There is increased incidence of different co infections including fungal from severe cases of covid-19 requiring ICU care from different parts of the world. None of the patients in our report had any predisposing lung conditions and none of them were on long term steroids treatment. Out of the three cases, two cases clinically improved dramatically after initiation of antifungals. Second case deteriorated even before culture diagnosis was established and the patient died before antifungals could be started. So, possibility of a fungal infection should be always ruled out in all COVID-19 pneumonia cases without any clinical improvement after standard treatment and intensive care. Early diagnosis and treatment will help improve clinical outcomes in such cases.

Early diagnosis of bloodstream infections in the intensive care unit using machine-learning algorithms

2020 ◽  
Vol 46 (3) ◽  
pp. 454-462 ◽  
Author(s):  
Michael Roimi ◽  
Ami Neuberger ◽  
Anat Shrot ◽  
Mical Paul ◽  
Yuval Geffen ◽  
...  
Keyword(s):  
Machine Learning ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Early Diagnosis ◽  
Learning Algorithms ◽  
Bloodstream Infections ◽  
Machine Learning Algorithms

scholarly journals Legionnaires’ Disease Complicated with Rhabdomyolysis and Acute Kidney Injury in an AIDS Patient

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Karan Seegobin ◽  
Satish Maharaj ◽  
Cherisse Baldeo ◽  
Julio Perez Downes ◽  
Pramod Reddy
Keyword(s):  
Renal Failure ◽  
Intensive Care ◽  
Early Diagnosis ◽  
Legionella Pneumophila ◽  
Relevant Literature ◽  
Ventilatory Support ◽  
Complete Recovery ◽  
Chronic Obstructive ◽  
High Morbidity ◽  
Lung Field

Objective. To present a case of an uncommon triad of Legionella pneumonia, rhabdomyolysis, and renal failure, with review of the relevant literature. Case. A 51-year-old with a history of human immunodeficiency virus (HIV), chronic obstructive pulmonary disease (COPD), and hypertension presented with fever, cough, and shortness of breath over four days. Chest X-ray showed consolidation in left lower lung field; urine was positive for Legionella antigen and myoglobin; creatine kinase was 51092U/L; creatine was 6.9 mg/dL, and his CD4 count was 41 cells/ul. He was managed with azithromycin and levofloxacin and further required dialysis and ventilatory support in the intensive care unit due to renal failure and respiratory failure. He responded well to the treatment and made a complete recovery. Legionella pneumophila infection is a recognized but rare cause of rhabdomyolysis with high morbidity and mortality when there is extrapulmonary involvement. Early diagnosis and appropriate treatment is essential to improve outcomes. Conclusion. Physicians should consider Legionella pneumonia in patients with rhabdomyolysis, renal failure, and respiratory symptoms. Early diagnosis and treatment have been shown to have good clinical response. Timely intensive care management, together with early and judicious use of dialysis in patients complicated with rhabdomyolysis and renal failure, may lead to good outcomes.

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