Introduction. Sedation is the reduction of irritability or agitation by the
use of certain drugs mostly to facilitate therapeutic or diagnostic
procedures. Scales for evaluation of the depth of sedation. Riker
Sedation-Agitation Scale and Richmond Agitation-Sedation Scale are the most
commonly used scales. Drugs. Sedation is generally produced by using
medications from the group of opioids, benzodiazepines, intravenous and
inhalation general anesthetic agents, neuroleptics, phenothiazines,
?-agonists and barbiturates. Adverse effects of sedatives. Sedation is
often associated with hypotension, prolonged mechanical ventilation and
longer time on respiratory support, higher frequency of delirium,
immunosuppression, deep vein thrombosis, increased risk for development of
nosocomial pneumonia, all of which leads to the prolonged recovery time.
Conclusion. Sedatives currently used in intensive care units are widely
used, but they have limitations. The goal is to get the desired level of
sedation with as few side effects as possible.