scholarly journals Significance of respiratory isolates of Mycobacterium avium complex in HIV positive and HIV negative patients

2000 ◽  
Vol 4 (3) ◽  
pp. 134-139 ◽  
Author(s):  
Bindu Raju ◽  
Neil W. Schluger
Keyword(s):  
Mycobacterium Avium ◽  
Mycobacterium Avium Complex ◽  
Hiv Positive ◽  
Hiv Negative

scholarly journals Gastro-intestinal Mycobacterium avium complex as a cause of anaemia

2010 ◽  
Vol 11 (2) ◽  
Author(s):  
Annemarie Van de Vyver ◽  
Adele Visser
Keyword(s):  
Chronic Disease ◽  
Mycobacterium Avium Complex ◽  
Blood Count ◽  
Clinical Case ◽  
Population Group ◽  
Common Finding ◽  
Full Blood Count ◽  
Hiv Positive ◽  
Anaemia Of Chronic Disease ◽  
Hiv Negative

Anaemia is a relatively common finding in HIV-positive patients, with rates (among females) as high as 37%, compared with their HIV negative counterparts (17%). Anaemia of chronic disease plays a very important role in this population group, and is estimated to occur in 18 - 95% of cases. For this reason, it is imperative to distinguish this condition from other underlying or concurrent causes of anaemia that may warrant treatment. This clinical case illustrates the value of critically evaluating the parameters of a full blood count and haematinic screen, to so determine which patients warrant further workup.

scholarly journals Relationship between IS901 in theMycobacterium avium Complex Strains Isolated from Birds, Animals, Humans, and the Environment and Virulence for Poultry

2000 ◽  
Vol 7 (2) ◽  
pp. 212-217 ◽  
Author(s):  
Ivo Pavlik ◽  
Petra Svastova ◽  
Jiri Bartl ◽  
Lenka Dvorska ◽  
Ivan Rychlik
Keyword(s):  
Human Immunodeficiency Virus ◽  
Mycobacterium Avium ◽  
Insertion Sequence ◽  
Animal Species ◽  
Bird Species ◽  
Hiv Positive ◽  
Immunodeficiency Virus ◽  
Hiv Negative

ABSTRACT A total of 738 strains of Mycobacterium avium complex (MAC) were examined in biological experiments on poultry by use of PCR methods with primers for detection of the insertion sequence IS901. Serotype strains of MAC from all known 28 serotypes were examined. Further strains were isolated from human immunodeficiency virus (HIV)-negative and HIV-positive patients, 6 animal species, 17 bird species, and the environment. Of 165 strains virulent for poultry, characterized by generalized tuberculosis, 164 strains contained IS901, a result which is statistically highly significant (P, 0.01). The remaining 573 strains were nonvirulent; however, IS901 was present in 24 strains. From among 20 strains of serotypes 1, 2, and 3, IS901 was found in 15 strains, only 5 of which were virulent for poultry. The remaining 111 strains, of serotypes 4 to 28, were nonvirulent and did not incorporate IS901. None of the 152 strains isolated from humans was virulent for poultry, including 12 strains which were IS901 positive.

scholarly journals Molecular epidemiology of Mycobacterium avium complex isolated from patients with and without AIDS in Brazil and England

1999 ◽  
Vol 122 (3) ◽  
pp. 435-440 ◽  
Author(s):  
M. A. S. TELLES ◽  
M. D. YATES ◽  
M. CURCIO ◽  
S. Y. M. UEKI ◽  
M. PALACI ◽  
...  
Keyword(s):  
Molecular Epidemiology ◽  
Mycobacterium Avium ◽  
Gel Electrophoresis ◽  
Mycobacterium Avium Complex ◽  
Opportunistic Pathogen ◽  
Pulsed Field Gel Electrophoresis ◽  
The World ◽  
Unique Strain ◽  
Over Time ◽  
Hiv Negative

Mycobacterium avium complex (MAC) is ubiquitous throughout the world. It is an opportunistic pathogen in AIDS patients but the number of cases in HIV negative patients is also increasing. The aim of this study was to determine whether patients were being infected with different MAC strains or whether one strain was dominant. DNA obtained from isolates in Brazil and England were compared using pulsed field gel electrophoresis (PFGE). Strains from 22 Brazilian patients clustered into 7 groups but 68/90 patients had a unique strain. In all patients, Brazilian and English, the same strain was isolated repeatedly over time, some over several years. This study shows that it is most likely that Man is infected from the environment and that one strain can survive without change for many years both in the environment and in Man.

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